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Source: Annals of Oncology
Drug: Alimta

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Total 1 results found since Jan 2013.

Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools
ConclusionsThese findings identify for the first time PCFT as a novel mesothelioma prognostic biomarker, prompting prospective trials for its validation. Moreover, preclinical data suggest that targetingPCFT-promoter methylation might eradicate pemetrexed-resistant cells characterized by low-PCFT expression.
Source: Annals of Oncology - September 7, 2017 Category: Cancer & Oncology Source Type: research