Filtered By:
Cancer: Non-Hodgkin's Lymphoma
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 16 results found since Jan 2013.
Abstract 348: JMJD3 promotes the survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms
Diffuse large B-cell lymphoma (DLBCL), the most common form of non-Hodgkin's lymphoma, comprises multiple biologically and clinically distinct subtypes including germinal centre B-cell-like (GCB) and activated B-cell-like (ABC) DLBCL. Dysreguation of genes related with B cell differentiation contributes to the tumorigenesis of DLBCL; the. Jumonji domain containing-3 (JMJD3), a histone 3 Lys27 (H3K27) demethylase, plays a known role in antigen-driven B-cell differentiation in GCB cells. But the mechanism of JMJD3 in DLBCL progression remains poorly uncerstood. Here we show that JMJD3 exerts an anti-apoptotic effect in both ...
Source: Cancer Research - September 30, 2014 Category: Cancer & Oncology Authors: Zhang, Y. Tags: Molecular and Cellular Biology Source Type: research
