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Source: Journal of Thoracic Disease

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Total 1254 results found since Jan 2013.

Exploration of the shared genes and signaling pathways between lung adenocarcinoma and idiopathic pulmonary fibrosis
CONCLUSIONS: ECM-related mechanisms may be the underlying link between LC and IPF. A total of 7 shared genes were identified as potential diagnostic markers and therapeutic targets for LUAD and IPF.PMID:37426132 | PMC:PMC10323588 | DOI:10.21037/jtd-22-1522
Source: Journal of Thoracic Disease - July 10, 2023 Category: Respiratory Medicine Authors: Houqiang Li Wenmiao Wang Zhanghao Huang Peng Zhang Lei Liu Xinyu Sha Silin Wang You Lang Zhou Jiahai Shi Source Type: research

Effects of dexmedetomidine on inflammation and pulmonary function after thoracoscopic surgery for lung cancer: a systematic review and meta-analysis
CONCLUSIONS: In summary, the use of Dex in lung cancer patients after radical surgery can reduce serum inflammatory factors, and this may play an important role in postoperative inflammatory reaction and improving lung function.PMID:37426124 | PMC:PMC10323582 | DOI:10.21037/jtd-23-651
Source: Journal of Thoracic Disease - July 10, 2023 Category: Respiratory Medicine Authors: Yu Xu Yi Zhou James D Maloney Guofa Shan Source Type: research

Exploration of the shared genes and signaling pathways between lung adenocarcinoma and idiopathic pulmonary fibrosis
CONCLUSIONS: ECM-related mechanisms may be the underlying link between LC and IPF. A total of 7 shared genes were identified as potential diagnostic markers and therapeutic targets for LUAD and IPF.PMID:37426132 | PMC:PMC10323588 | DOI:10.21037/jtd-22-1522
Source: Journal of Thoracic Disease - July 10, 2023 Category: Respiratory Medicine Authors: Houqiang Li Wenmiao Wang Zhanghao Huang Peng Zhang Lei Liu Xinyu Sha Silin Wang You Lang Zhou Jiahai Shi Source Type: research

Effects of dexmedetomidine on inflammation and pulmonary function after thoracoscopic surgery for lung cancer: a systematic review and meta-analysis
CONCLUSIONS: In summary, the use of Dex in lung cancer patients after radical surgery can reduce serum inflammatory factors, and this may play an important role in postoperative inflammatory reaction and improving lung function.PMID:37426124 | PMC:PMC10323582 | DOI:10.21037/jtd-23-651
Source: Journal of Thoracic Disease - July 10, 2023 Category: Respiratory Medicine Authors: Yu Xu Yi Zhou James D Maloney Guofa Shan Source Type: research

Obesity and lung cancer-a narrative review
CONCLUSIONS: The obesity paradox may arise due to the improper use of BMI as a measure of body composition. Measures of central obesity better portray the deleterious effects of obesity and are more appropriate to be discussed when talking about lung cancer. The use of obesity metrics based on anthropometric measurements and imaging modalities has been shown to be feasible and practical. However, a lack of standardization makes it difficult to interpret the results of studies using these metrics. Further research must be done to understand the association between these obesity metrics and lung cancer.PMID:37324095 | PMC:PM...
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yeshwanth Vedire Sukumar Kalvapudi Sai Yendamuri Source Type: research

Prediction of target genes in community-acquired pneumonia based on the bioinformatics method
CONCLUSIONS: The identification of the key gene IL7R and the related signaling pathways extend understanding of the pathogenesis of CAP and provide a theoretical basis for clinical targeted therapy research.PMID:37324088 | PMC:PMC10267904 | DOI:10.21037/jtd-23-592
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yangsong Zuo Wenyi Shen Guiming Chen Huailian Liu Na Liu Ting Xu Juan Pu Source Type: research

Obesity and lung cancer-a narrative review
CONCLUSIONS: The obesity paradox may arise due to the improper use of BMI as a measure of body composition. Measures of central obesity better portray the deleterious effects of obesity and are more appropriate to be discussed when talking about lung cancer. The use of obesity metrics based on anthropometric measurements and imaging modalities has been shown to be feasible and practical. However, a lack of standardization makes it difficult to interpret the results of studies using these metrics. Further research must be done to understand the association between these obesity metrics and lung cancer.PMID:37324095 | PMC:PM...
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yeshwanth Vedire Sukumar Kalvapudi Sai Yendamuri Source Type: research

Prediction of target genes in community-acquired pneumonia based on the bioinformatics method
CONCLUSIONS: The identification of the key gene IL7R and the related signaling pathways extend understanding of the pathogenesis of CAP and provide a theoretical basis for clinical targeted therapy research.PMID:37324088 | PMC:PMC10267904 | DOI:10.21037/jtd-23-592
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yangsong Zuo Wenyi Shen Guiming Chen Huailian Liu Na Liu Ting Xu Juan Pu Source Type: research

Obesity and lung cancer-a narrative review
CONCLUSIONS: The obesity paradox may arise due to the improper use of BMI as a measure of body composition. Measures of central obesity better portray the deleterious effects of obesity and are more appropriate to be discussed when talking about lung cancer. The use of obesity metrics based on anthropometric measurements and imaging modalities has been shown to be feasible and practical. However, a lack of standardization makes it difficult to interpret the results of studies using these metrics. Further research must be done to understand the association between these obesity metrics and lung cancer.PMID:37324095 | PMC:PM...
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yeshwanth Vedire Sukumar Kalvapudi Sai Yendamuri Source Type: research

Prediction of target genes in community-acquired pneumonia based on the bioinformatics method
CONCLUSIONS: The identification of the key gene IL7R and the related signaling pathways extend understanding of the pathogenesis of CAP and provide a theoretical basis for clinical targeted therapy research.PMID:37324088 | PMC:PMC10267904 | DOI:10.21037/jtd-23-592
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yangsong Zuo Wenyi Shen Guiming Chen Huailian Liu Na Liu Ting Xu Juan Pu Source Type: research

Obesity and lung cancer-a narrative review
CONCLUSIONS: The obesity paradox may arise due to the improper use of BMI as a measure of body composition. Measures of central obesity better portray the deleterious effects of obesity and are more appropriate to be discussed when talking about lung cancer. The use of obesity metrics based on anthropometric measurements and imaging modalities has been shown to be feasible and practical. However, a lack of standardization makes it difficult to interpret the results of studies using these metrics. Further research must be done to understand the association between these obesity metrics and lung cancer.PMID:37324095 | PMC:PM...
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yeshwanth Vedire Sukumar Kalvapudi Sai Yendamuri Source Type: research

Prediction of target genes in community-acquired pneumonia based on the bioinformatics method
CONCLUSIONS: The identification of the key gene IL7R and the related signaling pathways extend understanding of the pathogenesis of CAP and provide a theoretical basis for clinical targeted therapy research.PMID:37324088 | PMC:PMC10267904 | DOI:10.21037/jtd-23-592
Source: Journal of Thoracic Disease - June 16, 2023 Category: Respiratory Medicine Authors: Yangsong Zuo Wenyi Shen Guiming Chen Huailian Liu Na Liu Ting Xu Juan Pu Source Type: research