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Source: Annals of Laboratory Medicine

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Evaluation of Cellular Responses to ChAdOx1-nCoV-19 and BNT162b2 Vaccinations
Ann Lab Med. 2023 May 1;43(3):290-294. doi: 10.3343/alm.2023.43.3.290. Epub 2022 Dec 22.ABSTRACTWhile numerous studies have evaluated humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, data on the cellular responses to these vaccines remain sparse. We evaluated T cell responses to ChAdOx1-nCoV-19 and BNT162b2 vaccinations using an interferon gamma (IFN-γ) release assay (IGRA). ChAdOx1-nCoV-19- and BNT162b2-vaccinated participants initially showed stronger T cell responses than unvaccinated controls. The T cell response decreased over time and increased substantially after the admin...
Source: Annals of Laboratory Medicine - December 22, 2022 Category: Laboratory Medicine Authors: Tae Hwan Lee Minjeong Nam Jong Do Seo Hanah Kim Hae-Rim Kim Mina Hur Yeo-Min Yun Hee-Won Moon Source Type: research