Resistance to African swine fever virus among African domestic pigs appears to be associated with a distinct polymorphic signature in the RelA gene and upregulation of RelA transcription
African swine fever virus (ASFV) is a highly contagious and fatal hemorrhagic disease of domestic pigs, which poses a major threat to the swine industry worldwide. Studies have shown that indigenous African pi... (Source: Virology Journal)
Source: Virology Journal - April 24, 2024 Category: Virology Authors: Patrick N. Bisimwa, Juliette R. Ongus, Ronald Tonui, Espoir B. Bisimwa and Lucilla Steinaa Tags: Research Source Type: research
A randomized clinical trial investigating the impact of magnesium supplementation on clinical and biochemical measures in COVID-19 patients
This study sought to examine the impact of magnesium supplementation on clinical outcomes and biochemical factors among hospitalized patients with COVID-19. (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Sepideh Rostami, Seyed Mohammad Alavi, Robab Daghagheleh, Elham Maraghi and Seyed Ahmad Hosseini Tags: Research Source Type: research
Effect of S-region mutations on HBsAg in HBsAg-negative HBV-infected patients
Occult HBV infection (OBI) is a special form of hepatitis B virus (HBV) infection that may cause Liver cirrhosis and hepatocellular carcinoma, causing significant harm to patients. Given the insidious nature o... (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Hui Liu, Shuxiang Chen, Xin Liu and Jinli Lou Tags: Research Source Type: research
Nonlinear relationship between viral load and TCT in single/multiple HPV52 infection
To determine the correlation between HPV (human papillomavirus) 52 viral load, multiple infections and ThinPrep cytology test (TCT), to inform clinical management of HPV52-positive women after cervical cancer ... (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Bingbing Ma, Jie Zhou, Weijuan Zhou, Zhanzhong Ma, Juan Chen and Hongbo Hu Tags: Research Source Type: research
Computational analysis of affinity dynamics between the variants of SARS-CoV-2 spike protein (RBD) and human ACE-2 receptor
The novel coronavirus SARS-CoV-2 resulted in a significant worldwide health emergency known as the COVID-19 pandemic. This crisis has been marked by the widespread of various variants, with certain ones causin... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Nishad Sultana, S. N. Nagesha, C. N. Lakshminarayana Reddy, B. N. Ramesh, S. Shyamalamma, K. S. Shashidhara, K. M. Satish, C. Pradeep and G. D Vidyadhar Tags: Research Source Type: research
MST1/2 exerts a pivotal role in inducing neuroinflammation and Coxsackievirus-A10 replication by interacting with innate immunity
Coxsackievirus-A10 (CV-A10), responsible for the hand, foot and mouth disease (HFMD) pandemic, could cause serious central nervous system (CNS) complications. The underlying molecular basis of CV-A10 and host ... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Yajie Hu, Minigmei Zhong, Yaming Lv, Wei Zhao, Baojiang Qian, Jie Song and Yunhui Zhang Tags: Research Source Type: research
Stability and integrity of self-assembled bovine parvovirus virus ‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment
Bovine parvovirus (BPV) is an autonomous DNA virus with a smaller molecular size and subtle differences in its structural proteins, unlike other animal parvoviruses. More importantly, this virus has the potent... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Ashenafi Kiros Wubshet, Guo-xiu Li, Qian Li, Jun-Fei Dai, Yao-Zhong Ding, Luoyi Zhou, Min Qu, Yang Wang, Zhongyuan Ma, Gebremeskel Mamu Werid, Birhanu Hadush Abera, Asmelash Tassew Kebede, Yuefeng Sun, Xiangping Yin, Yongsheng Liu and Zhang Jie Tags: Methodology Source Type: research
Deciphering the virome of Chunkung (Cnidium officinale) showing dwarfism-like symptoms via a high-throughput sequencing analysis
Viruses have notable effects on agroecosystems, wherein they can adversely affect plant health and cause problems (e.g., increased biosecurity risks and economic losses). However, our knowledge of their divers... (Source: Virology Journal)
Source: Virology Journal - April 15, 2024 Category: Virology Authors: Mesele Tilahun Belete, Se Eun Kim, Workitu Firmosa Gudeta, Davaajargal Igori, Jeong A. Kwon, Su-Heon Lee and Jae Sun Moon Tags: Research Source Type: research
Immunopathological investigation and genetic evolution of Avian leukosis virus Subgroup-J associated with myelocytomatosis in broiler flocks in Egypt
Avian leukosis virus Subgroup-J (ALV-J) is a rapidly oncogenic evolving retrovirus infecting a variety of avian species; causing severe economic losses to the local poultry industry. (Source: Virology Journal)
Source: Virology Journal - April 10, 2024 Category: Virology Authors: Ahmed Fotouh, Eman Abd El-Menamm Shosha, Ali Mahmood Zanaty and Marwa Mostafa Darwesh Tags: Research Source Type: research
Recombination analysis on the receptor switching event of MERS-CoV and its close relatives: implications for the emergence of MERS-CoV
PlMERS-CoV is a coronavirus known to cause severe disease in humans, taxonomically classified under the subgenus Merbecovirus. Recent findings showed that the close relatives of MERS-CoV infecting vespertillionid... (Source: Virology Journal)
Source: Virology Journal - April 10, 2024 Category: Virology Authors: Jarel Elgin Tolentino, Spyros Lytras, Jumpei Ito and Kei Sato Tags: Research Source Type: research
Isolation and genetic characteristics of Novel H4N1 Avian Influenza viruses in ChongQing, China
Avian influenza viruses (AIVs) constitute significant zoonotic pathogens encompassing a broad spectrum of subtypes. Notably, the H4 subtype of AIVs has a pronounced ability to shift hosts. The escalating preva... (Source: Virology Journal)
Source: Virology Journal - April 10, 2024 Category: Virology Authors: Jinyue He, Jing Deng, Xianxian Wen, Mengyuan Yan, Yang Liu, Yunqiu Zhou, XuBin Du, Han Yang and Xiaobin Peng Tags: Research Source Type: research
Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza
Influenza and SARS-CoV-2 are two major respiratory pathogens that cocirculate in humans and cause serious illness with the potential to exacerbate disease in the event of co-infection. To develop a bivalent va... (Source: Virology Journal)
Source: Virology Journal - April 9, 2024 Category: Virology Authors: Ekaterina Stepanova, Irina Isakova-Sivak, Daria Mezhenskaya, Sergei Niskanen, Victoria Matyushenko, Ekaterina Bazhenova, Alexandra Rak, Pei Fong Wong, Polina Prokopenko, Tatiana Kotomina, Elena Krutikova, Sergei Legotskiy, Bogdan Neterebskii, Tatiana Ostr Tags: Research Source Type: research
Development of monoclonal antibodies against oropouche virus and its applicability to immunohistochemical diagnosis
Orthobunyavirus oropouche ense virus (OROV), the causative agent of Oropouche fever, is widely dispersed in Brazil and South America, causing sporadic outbreaks. Due to the similarity of initial clinical symptoms... (Source: Virology Journal)
Source: Virology Journal - April 8, 2024 Category: Virology Authors: Ana Paula Andreolla, Alessandra Abel Borges, Seigo Nagashima, Caroline Busatta Vaz de Paula, Lucia de Noronha, Nilson I.T. Zanchin, Juliano Bordignon and Claudia Nunes Duarte dos Santos Tags: Research Source Type: research
A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis
Although macrophages are now recognized as an essential part of the HIV latent reservoir, whether and how viral latency is established and reactivated in these cell types is poorly understood. To understand th... (Source: Virology Journal)
Source: Virology Journal - April 5, 2024 Category: Virology Authors: Javan K. Kisaka, Daniel Rauch, Malachi Griffith and George B. Kyei Tags: Research Source Type: research
Hepatitis B relapse after entecavir or tenofovir alafenamide cessation under anti-viral prophylaxis for cancer chemotherapy
No study has comparing hepatitis B virus (HBV) relapse rates among patients with both cancer and hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) who completed anti-viral prophylaxis for chemot... (Source: Virology Journal)
Source: Virology Journal - April 3, 2024 Category: Virology Authors: Hsin-Wei Fang, Po-Lin Tseng, Tsung-Hui Hu, Jing-Houng Wang, Chao-Hung Hung, Sheng-Nan Lu and Chien-Hung Chen Tags: Research Source Type: research
