Optimizing COVID-19 treatment in immunocompromised patients: early combination therapy with remdesivir, nirmatrelvir/ritonavir and sotrovimab
Morbidity and mortality are higher in immunocompromised patients affected by COVID-19 than in the general population. Some authors have successfully used antiviral combination, but never in the early phase of ... (Source: Virology Journal)
Source: Virology Journal - December 15, 2023 Category: Virology Authors: Ivan Gentile, Maria Foggia, Maria Silvitelli, Alessia Sardanelli, Letizia Cattaneo and Giulio Viceconte Tags: Brief Report Source Type: research
Epidemiological surveillance of respiratory viral infections in SARS-CoV-2-negative samples during COVID-19 pandemic in Iran
To improve the patient care, public health surveillance, and infection control, it is crucial to identify the presence and frequency of the common respiratory infections in individuals with COVID-19 symptoms b... (Source: Virology Journal)
Source: Virology Journal - December 13, 2023 Category: Virology Authors: Ali Maleki, Parvaneh Mehrbod, Farah Bokharaei-Salim, Sana Eybpoosh, Mahsa Tavakoli, Azita Eshratkhah Mohammadnejad, Zahra Hosseini, Setareh Kashanian, Laya Farhan Asadi, Mostafa Salehi-Vaziri and Fatemeh Fotouhi Tags: Research Source Type: research
Armstrong strain lymphocytic choriomeningitis virus infection after accidental laboratory exposure
Lymphocytic choriomeningitis virus (LCMV) is a human pathogen naturally present in wild rodents. In addition, LCMV is routinely used in immunology research as a model of viral infection in mice. The Armstrong ... (Source: Virology Journal)
Source: Virology Journal - December 12, 2023 Category: Virology Authors: Laurence Caron, Jean-S ébastien Delisle, James E Strong, Yvon Deschambault, Félix Lombard-Vadnais, Annie-Claude Labbé and Sylvie Lesage Tags: Case Report Source Type: research
Apoptosis is mediated by FeHV-1 through the intrinsic pathway and interacts with the autophagic process
Although FeHV-1 is a primary feline pathogen, little is known about its interactions with host cells. Its relationship with several cellular pathways has recently been described, whereas its interplay with the... (Source: Virology Journal)
Source: Virology Journal - December 12, 2023 Category: Virology Authors: Gianmarco Ferrara, Consiglia Longobardi, Maria Francesca Sgadari, Brunella Restucci, Giuseppe Iovane, Roberto Ciarcia, Ugo Pagnini and Serena Montagnaro Tags: Research Source Type: research
Development and evaluation of serological screening based on one dried plasma spot for HIV, syphilis, and HCV
In the effort to prevent and control HIV/AIDS, China has established a national sentinel surveillance system. However, some sentinel sites face limitations in environmental resources and accessibility, prompti... (Source: Virology Journal)
Source: Virology Journal - December 11, 2023 Category: Virology Authors: Jie-qiong Ma, Ya-nan Ren, Shi-yuan Wen, Ao-bo Dong, Wen-ge Xing and Yan Jiang Tags: Methodology Source Type: research
Down-regulated TAB1 suppresses the replication of Coxsackievirus B5 via activating the NF- κB pathways through interaction with viral 3D polymerase
Coxsackievirus Group B type 5 (CVB5), an important pathogen of hand-foot-mouth disease, is also associated with neurological complications and poses a public health threat to young infants. Among the CVB5 prot... (Source: Virology Journal)
Source: Virology Journal - December 10, 2023 Category: Virology Authors: Jiayu Zhang, Peiying Teng, Bo Sun, Jihong Zhang, Xiaoshuang Zhou and Wei Chen Tags: Research Source Type: research
Learning from cerebrospinal fluid drug-resistant HIV escape-associated encephalitis: a case report
In the era of antiretroviral therapy (ART), central nervous system (CNS) complications in patients with human immunodeficiency virus (HIV) infection are sometimes associated with cerebrospinal fluid (CSF) vira... (Source: Virology Journal)
Source: Virology Journal - December 10, 2023 Category: Virology Authors: Jing Kang, Ziqiu Wang, Ying Zhou, Wen Wang and Ying Wen Tags: Case Report Source Type: research
Identification of the protein coding capability of coronavirus defective viral genomes by mass spectrometry
In this study, we aimed to examine ... (Source: Virology Journal)
Source: Virology Journal - December 7, 2023 Category: Virology Authors: Ching-Hung Lin, Feng-Cheng Hsieh, Chien-Chen Lai, Wei-Chen Wang, Cheng-Yu Kuo, Chun-Chun Yang, Hsuan-Wei Hsu, Hon-Man-Herman Tam, Cheng-Yao Yang and Hung-Yi Wu Tags: Brief Report Source Type: research
Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses
Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate... (Source: Virology Journal)
Source: Virology Journal - December 4, 2023 Category: Virology Authors: Bruno Stein Barbosa Menechino, Rodrigo Bentes Kato, Helena Cristina Ferreira Franz, Pedro Eduardo Almeida da Silva, Marcus Corat and Daniel Ferreira de Lima Neto Tags: Brief Report Source Type: research
Bioinformatics analysis of immune characteristics in tumors with alternative carcinogenesis pathways induced by human papillomaviruses
Human papillomaviruses (HPVs) induce a subset of head and neck squamous cell carcinomas (HNSCC) and anogenital cancers, particularly cervical cancer (CC). The major viral proteins that contribute to tumorigene... (Source: Virology Journal)
Source: Virology Journal - December 4, 2023 Category: Virology Authors: Michal Smahel and Jaroslav Nunvar Tags: Research Source Type: research
Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis
Cervical cancer (CC) is one of the most common gynecologic tumors among women around the world. Although the etiological role of human papillomavirus (HPV) in CC is well established, other factors in CC carcin... (Source: Virology Journal)
Source: Virology Journal - December 4, 2023 Category: Virology Authors: Han Zhang, Shunli Cai, Yuan Xia, Yangxuan Lin, Guozhong Zhou, Yinghui Yu and Min Feng Tags: Review Source Type: research
HIV transmission and associated factors under the scale-up of HIV antiretroviral therapy: a population-based longitudinal molecular network study
To evaluate the prevention efficacy of scaling up HIV/AIDS antiretroviral therapy (ART) on HIV transmission at the population level and determine associated factors of HIV secondary transmission. (Source: Virology Journal)
Source: Virology Journal - December 4, 2023 Category: Virology Authors: Yi Chen, Zhiqiang Cao, Jianjun Li, Jin Chen, Qiuying Zhu, Shujia Liang, Guanghua Lan, Hui Xing, Lingjie Liao, Yi Feng, Yiming Shao, Yuhua Ruan and Huanhuan Chen Tags: Research Source Type: research
Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variants
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has challenged the effectiveness of current therapeutic regimens. Here, we aimed to develop a potent SARS-CoV-2 antibody w... (Source: Virology Journal)
Source: Virology Journal - December 1, 2023 Category: Virology Authors: Hae Li Ko, Deuk-ki Lee, Younghyeon Kim, Hui Jeong Jang, Youn Woo Lee, Ho-Young Lee, Sang-Hyuk Seok, Jun Won Park, Jin-Kyung Limb, Da In On, Jun-Won Yun, Kwang-Soo Lyoo, Daesub Song, Minjoo Yeom, Hanbyeul Lee, Je Kyung Seong & hellip; Tags: Research Source Type: research
HLA-DR genetic polymorphisms and hepatitis B virus mutations affect the risk of hepatocellular carcinoma in Han Chinese population
Human leucocyte antigen (HLA)-DR plays a crucial role in the immune response against hepatitis B virus (HBV). We aimed to investigate the associations of HLA-DR single nucleotide polymorphisms (SNPs) with the gen... (Source: Virology Journal)
Source: Virology Journal - November 30, 2023 Category: Virology Authors: Yubao Zhao, Kun Chen, Hui Yang, Feng Zhang, Lu Ding, Yan Liu, Le Zhang, Yuchen Zhang, Huiliang Wang and Yang Deng Tags: Research Source Type: research
Alfalfa vein mottling virus, a novel potyvirid infecting Medicago sativa L.
We have recently identified a novel virus detected in alfalfa seed material. The virus was tentatively named alfalfa-associated potyvirus 1, as its genomic fragments bore similarities with potyvirids. In this ... (Source: Virology Journal)
Source: Virology Journal - November 30, 2023 Category: Virology Authors: Lev G. Nemchinov, Olga A. Postnikova, William M. Wintermantel, John C. Palumbo and Sam Grinstead Tags: Research Source Type: research
