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Total 108908 results found since Jan 2013.

MiRNA a New Insight in Metabolic and Human Diseases: A Review
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):102-110. doi: 10.14715/cmb/2023.69.8.16.ABSTRACTThe purpose of this research is to examine existing studies on the association between microRNAs (miRNA) and age-related disorders. The miRNAs are small, noncoding RNA molecules with the ability to regulate gene expression. These are well-established in extracellular circulation, including various types of diseases such as cancer, cardiovascular diseases, and diabetes. Similarly, several miRNAs are associated with certain age-related conditions, such as increased miR-21 expression in cancer patients. Besides that, the miR-122 ...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Ibrahim Jafri Source Type: research

Uncontrolled blood pressure according to ambulatory blood pressure monitoring values in pregnant women is poorly predictable
Kardiol Pol. 2023;81(7-8):763-765. doi: 10.33963/KP.a2023.0104.NO ABSTRACTPMID:37711051 | DOI:10.33963/KP.a2023.0104
Source: Polish Heart Journal - September 15, 2023 Category: Cardiology Authors: Ewa Wojciechowska Katarzyna Cienszkowska Marta Ludwiczak Piotr Sobieraj Piotr Gryglas Jacek Lewandowski Source Type: research

Large unstained cells count is a useful predictor of coronary artery disease co-existence in patients with severe aortic stenosis
Kardiol Pol. 2023;81(7-8):769-771. doi: 10.33963/KP.a2023.0111.NO ABSTRACTPMID:37711047 | DOI:10.33963/KP.a2023.0111
Source: Polish Heart Journal - September 15, 2023 Category: Cardiology Authors: Tomasz Urbanowicz Anna Olasi ńska-Wiśniewska Kajetan Grodecki Zuzanna Fryska Anna Komosa Pawe ł Uruski Artur Radziemski Krzysztof J Filipiak Andrzej Tykarski Marek Jemielity Source Type: research

Short Versus Long Duration of Dual Antiplatelet Therapy After Second-Generation Drug-Eluting Stents Implantation in Patients with Diabetes
CONCLUSION: This meta-analysis showed no statistically significant benefit of longer DAPT over shorter DAPT therapy in patients undergoing PCI with drug-eluting stent in patients with diabetes.PMID:37713685 | DOI:10.1097/MJT.0000000000001519
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Manesh Kumar Gangwani Muhammad Aziz Paul Chacko Asif Mahmood Muhammad Ali Fnu Priyanka Siraj Munir Abeer Aziz Shazib Sagheer Wade Lee-Smith Om Parkash Devesh Rai Bipul Baibhav Wilbert S Aronow Source Type: research

Cardiac Insulin Resistance in Subjects With Metabolic Syndrome Traits and Early Subclinical Atherosclerosis
CONCLUSIONS: Apparently healthy individuals without cardiac 18F-FDG uptake have higher HOMA-IR and higher prevalence of MetS traits, cardiovascular risk factors, and early atherosclerosis. An improvement in cardiometabolic profile is associated with the recovery of myocardial 18F-FDG uptake at follow-up.PMID:37713581 | DOI:10.2337/dc23-0871
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Ana Devesa Valentin Fuster Ravi Vazirani In és García-Lunar Bel én Oliva Samuel Espa ña Andrea Moreno-Arciniegas Javier Sanz Cristina Perez-Herreras H éctor Bueno Enrique Lara-Pezzi Ana Garc ía-Alvarez Vicente Mart ínez de Vega Leticia Fern ández- Source Type: research

The Characteristics of Macrophage Heterogeneity in Atherosclerotic Aortas
J Cardiovasc Transl Res. 2023 Sep 15. doi: 10.1007/s12265-023-10434-1. Online ahead of print.ABSTRACTMacrophage is the main effector cell during atherosclerosis. We applied single-cell RNA sequencing (scRNA) data to investigate the role of macrophage subsets in atherosclerosis. Monocyte and macrophage clusters were divided into 6 subclusters. Each subcluster's markers were calculated and validated by immunofluorescence. Elevated macrophage subclusters in the WD group were subject to enrichment pathway analysis and exhibited different phenotypes. Pseudotime analysis shows the subclusters originate from monocytes. We culture...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Yu-Jie Song Yu Ma Ting Meng Tao Zhuang Cheng-Chao Ruan Yan Li Guan-Nan Zhang Source Type: research

Editorial: Transient ischemic attack: standard-of-care model
Front Neurol. 2023 Aug 30;14:1278624. doi: 10.3389/fneur.2023.1278624. eCollection 2023.NO ABSTRACTPMID:37712086 | PMC:PMC10499352 | DOI:10.3389/fneur.2023.1278624
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Narayanaswamy Venketasubramanian Thanh G Phan Jiang Li John Van Ly Saeideh Aghayari Sheikh Neshin Source Type: research

Circulating Proteins and Mortality in CKD: A Proteomics Study of the AASK and ARIC Cohorts
CONCLUSIONS: Using large-scale proteomic analysis, proteins were reproducibly associated with mortality in 2 cohorts of participants with CKD.PLAIN-LANGUAGE SUMMARY: Patients with chronic kidney disease (CKD) have a high risk of premature death, with various pathophysiological processes contributing to this increased risk of mortality. This observational cohort study aimed to investigate the associations between circulating proteins and all-cause mortality in patients with CKD using large-scale proteomic analysis. The study analyzed data from the African American Study of Kidney Disease and Hypertension (AASK) study and va...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Nityasree Srialluri Aditya Surapaneni Pascal Schlosser Teresa K Chen Insa M Schmidt Eugene P Rhee Josef Coresh Morgan E Grams Source Type: research

Computed tomography angiography-based radiomics model to identify high-risk carotid plaques
CONCLUSIONS: The combined model of the radiomics features of carotid plaques and PVAT and the traditional CTA features significantly contributes to identifying high-risk carotid plaques compared with traditional CTA model.PMID:37711840 | PMC:PMC10498225 | DOI:10.21037/qims-23-158
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Chao Chen Wei Tang Yong Chen Wenhan Xu Ningjun Yu Chao Liu Zenghui Li Zhao Tang Xiaoming Zhang Source Type: research

Effect of dominant vertebral artery angle on basilar artery curvature and plaque
CONCLUSIONS: The dominant VA angle was independently associated with BA plaque, and a dominant VA angle greater than 80° may be a marker for a high risk of posterior circulation atherosclerosis.PMID:37711832 | PMC:PMC10498226 | DOI:10.21037/qims-23-74
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Yangchen Li Runcai Guo Xuebing Zhang Yang Yang Yuchun Yan Xinyu Yuan Ce Wang Sheng Xie Source Type: research

Safety, accuracy, and prediction of prognosis in patients with end-stage chronic kidney disease undergoing dobutamine stress cardiac magnetic resonance imaging
DISCUSSION: Dobutamine stress CMR is a safe and accurate diagnostic imaging technique in patients at advanced stages of chronic kidney disease. A reduced ejection fraction and the inability to reach the target heart rate are independent predictors of a poor outcome.PMID:37711564 | PMC:PMC10498284 | DOI:10.3389/fcvm.2023.1228691
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Lukas D Weberling Sebastian Seitz Janek Salatzki Andreas Ochs Ail ís C Haney Deborah Siry Jannick Heins Henning Steen Norbert Frey Florian Andr é Source Type: research

Oral microbiome mediated inflammation, a potential inductor of vascular diseases: a comprehensive review
Front Cardiovasc Med. 2023 Aug 30;10:1250263. doi: 10.3389/fcvm.2023.1250263. eCollection 2023.ABSTRACTThe dysbiosis of the oral microbiome and vascular translocation of the periodontopathic microorganism to peripheral blood can cause local and systemic extra-oral inflammation. Microorganisms associated with the subgingival biofilm are readily translocated to the peripheral circulation, generating bacteremia and endotoxemia, increasing the inflammation in the vascular endothelium and resulting in endothelial dysfunction. This review aimed to demonstrate how the dysbiosis of the oral microbiome and the translocation of oral...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Diego F Gualtero Gloria In és Lafaurie Diana Marcela Buitrago Yormaris Castillo Paula Katherine Vargas-Sanchez Diana Marcela Castillo Source Type: research

Endothelial activation and fibrotic changes are impeded by laminar flow-induced CHK1-SENP2 activity through mechanisms distinct from endothelial-to-mesenchymal cell transition
In this study, we have revealed a novel mechanism underlying the suppressive effects of L-flow on EC inflammation, migration, proliferation, apoptosis, and fibrotic changes through promoting CHK1-induced SENP2 S344 phosphorylation. The phospho-site mutation SENP2 S344A responds to L-flow through a distinct mechanism, which involves the upregulation of both mesenchymal and EC marker genes.PMID:37711550 | PMC:PMC10499395 | DOI:10.3389/fcvm.2023.1187490
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Minh T H Nguyen Masaki Imanishi Shengyu Li Khanh Chau Priyanka Banerjee Loka Reddy Velatooru Kyung Ae Ko Venkata S K Samanthapudi Young J Gi Ling-Ling Lee Rei J Abe Elena McBeath Anita Deswal Steven H Lin Nicolas L Palaskas Robert Dantzer Keigi Fujiwara M Source Type: research

2023 Chinese guideline for lipid management
Front Pharmacol. 2023 Aug 29;14:1190934. doi: 10.3389/fphar.2023.1190934. eCollection 2023.ABSTRACTAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of death among urban and rural residents in China, and elevated low-density lipoprotein cholesterol (LDL-C) is a risk factor for ASCVD. Considering the increasing burden of ASCVD, lipid management is of the utmost importance. In recent years, research on blood lipids has made breakthroughs around the world, hence a revision of Chinese guideline for lipid management is imperative, especially since the target lipid levels in the general population vary in respe...
Source: Atherosclerosis - September 15, 2023 Category: Cardiology Authors: Jian-Jun Li Shui-Ping Zhao Dong Zhao Guo-Ping Lu Dao-Quan Peng Jing Liu Zhen-Yue Chen Yuan-Lin Guo Na-Qiong Wu Sheng-Kai Yan Zeng-Wu Wang Run-Lin Gao Source Type: research

Platelet glycoprotein IIb/IIIa inhibitor tirofiban in clopidogrel-na ïve patients undergoing elective percutaneous coronary intervention
CONCLUSION: Ad-hoc PCI in clopidogrel-naïve patients who were treated with high-dose bolus of tirofiban followed by a clopidogrel loading dose immediately after the procedure appeared to be safe.PMID:37713051 | DOI:10.1007/s12471-023-01810-2
Source: Netherlands Heart Journal - September 15, 2023 Category: Cardiology Authors: Zarina Habibi Jasper Luijkx Ben C G Gho Mustafa Ilhan Leo F Veenstra Lex A W Ruiters Mera Stein Arnoud W J van 't Hof Saman Rasoul Source Type: research