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Source: Expert Review of Neurotherapeutics

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The role of Fecal Microbiota Transplantation (FMT) in treating patients with multiple sclerosis
Expert Rev Neurother. 2023 Aug 24:1-11. doi: 10.1080/14737175.2023.2250919. Online ahead of print.ABSTRACTINTRODUCTION: The associations between multiple sclerosis (MS) and altered intestinal microbiomes have clinicians considering the use of fecal microbiota transplantation (FMT). Animal data suggests that administering FMT from people with MS into healthy mice results in a microbiome with decreased abundance of Sutterella, reduced anti-inflammatory signals, increase in inflammation and experimental autoimmune encephalomyelitis (EAE). Animal studies that administered FMT (from normal healthy donors) into mice resulted in ...
Source: Expert Review of Neurotherapeutics - August 24, 2023 Category: Neurology Authors: George G Zhanel Rotem Keynan Yoav Keynan James A Karlowsky Source Type: research