Primary Immune Thrombocytopenic Purpura (ITP) and ITP Associated with Systemic Lupus Erythematosus: A Review of Clinical Characteristics and Treatment Modalities
Int J Rheumatol. 2024 Mar 1;2024:6650921. doi: 10.1155/2024/6650921. eCollection 2024.ABSTRACTImmune thrombocytopenic purpura (ITP) is an immune-mediated disorder characterized by the destruction of platelets and megakaryocytes due to autoantibodies against the platelet surface proteins. ITP without any apparent cause of thrombocytopenia is defined as primary ITP, and ITP in the setting of SLE is secondary ITP, which can be diagnosed after excluding other causes of thrombocytopenia by history, physical examination, and laboratory testing. Patients with ITP associated with SLE have higher median platelet count and less blee...
Source: International Journal of Rheumatology - March 11, 2024 Category: Rheumatology Authors: Krishna Prasad Bashyal Sangam Shah Calvin Ghimire Shravya Balmuri Pradip Chaudhary Sandip Karki Anuj Krishna Poudel Ashbina Pokharel Vishal Devarkonda Samina Hayat Source Type: research