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Specialty: Tropical Medicine
Vaccination: Veterinary Vaccinations
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Total 369 results found since Jan 2013.
Detection of Sporadic Outbreaks of Rift Valley Fever in Uganda through the National Viral Hemorrhagic Fever Surveillance System, 2017-2020
We report 52 human cases of laboratory-confirmed RVF from 2017 to 2020. The case fatality rate was 42%. Among those infected, 92% were males and 90% were adults (≥ 18 years). Clinical symptoms were characterized by fever (69%), unexplained bleeding (69%), headache (51%), abdominal pain (49%), and nausea and vomiting (46%). Most of the cases (95%) originated from central and western districts that are part of the cattle corridor of Uganda, where the main risk factor was direct contact with livestock (P = 0.009). Other predictors of RVF positivity were determined to be male gender (P = 0.001) and being a butcher (P = 0.04)...
Source: The American Journal of Tropical Medicine and Hygiene - March 13, 2023 Category: Tropical Medicine Authors: Luke Nyakarahuka Shannon Whitmer John Klena Stephen Balinandi Emir Talundzic Alex Tumusiime Jackson Kyondo Sophia Mulei Ketan Patel Jimmy Baluku Gloria Akurut Diana Namanya Kilama Kamugisha Caitlin Cossaboom Amy Whitesell Carson Telford James Graziano Joe Source Type: research
Informing One Health Anthrax Surveillance and Vaccination Strategy from Spatial Analysis of Anthrax in Humans and Livestock in Ha Giang Province, Vietnam (1999-2020)
This study identified spatial areas of high risk for anthrax and can inform One Health surveillance and livestock vaccination planning in contextual settings similar to Ha Giang province.PMID:36689942 | DOI:10.4269/ajtmh.22-0384
Source: The American Journal of Tropical Medicine and Hygiene - January 23, 2023 Category: Tropical Medicine Authors: Tan Luong Tat Thang Nguyen Van Binh Trinh Morgan A Walker Thi Thu Ha Hoang Quang Thai Pham Thi Mai Hung Tran Van Khang Pham Van Long Nguyen Thanh Long Pham Jason K Blackburn Source Type: research
Estimation of the Minimal Rift Valley Fever Virus Protective Neutralizing Antibody Titer in Human Volunteers Immunized with MP-12 Vaccine Based on Protection in a Mouse Model of Disease
Am J Trop Med Hyg. 2022 Sep 19:tpmd220356. doi: 10.4269/ajtmh.22-0356. Online ahead of print.ABSTRACTThe Rift Valley fever virus (RVFV) MP-12 vaccine is a promising human and veterinary vaccine. Although the vaccine elicited neutralizing antibody (nAb) in human volunteers, the minimal antibody titer that is needed to afford protection is unknown. Therefore, this study was conducted to determine the minimal nAb titer elicited by the RVFV MP-12 vaccine in human volunteers that protected mice against lethal RVFV challenge as a surrogate assessment of the protective efficacy of the vaccine. Among volunteers who were vaccinated...
Source: The American Journal of Tropical Medicine and Hygiene - September 19, 2022 Category: Tropical Medicine Authors: Douglas M Watts Jonna L B Westover Pedro M Palermo Kevin W Bailey John C Morrill George E Bettinger Thomas P Monath Darci R Smith Clarence J Peters Phillip R Pittman Jeanette Orbegozo Brian B Gowen Source Type: research
