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Procedure: Perfusion

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Total 26728 results found since Jan 2013.

Enhanced Perfusion During Advanced Life Support Improves Survival With Favorable Neurologic Function in a Porcine Model of Refractory Cardiac Arrest
Conclusion: Advanced life support with active compression-decompression plus intrathoracic pressure regulator significantly improved cerebral perfusion and 24-hour survival with favorable neurologic function. These findings support further evaluation of this new advanced life support methodology in humans.
Source: Critical Care Medicine - April 17, 2015 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research

Mannitol Improves Brain Tissue Oxygenation in a Model of Diffuse Traumatic Brain Injury*
Conclusion: The development of posttraumatic brain edema can limit the oxygen utilization by brain tissue without evidence of brain ischemia. Our findings indicate that an antiedematous agent such as mannitol can improve brain tissue oxygenation, possibly by limiting astrocyte swelling and restoring capillary perfusion.
Source: Critical Care Medicine - September 18, 2015 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research

Hypertonic Lactate to Improve Cerebral Perfusion and Glucose Availability After Acute Brain Injury*
We examined the effect of hypertonic lactate on cerebral perfusion (using transcranial Doppler) and brain energy metabolism (using cerebral microdialysis). The majority of subjects (13/23 = 57%) had reduced brain glucose availability (baseline pretreatment cerebral microdialysis glucose,
Source: Critical Care Medicine - September 15, 2018 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research

Outcomes Associated With Stage 1 Pressure Injuries: A Retrospective Cohort Study.
CONCLUSIONS: Stage 1 pressure injuries worsen in about one-third of patients (32.4%). Nurses should consider maximal treatment for patients who are older or who experience alterations in oxygen delivery or perfusion. PMID: 30385538 [PubMed - in process]
Source: American Journal of Critical Care - November 1, 2018 Category: Nursing Authors: Alderden J, Zhao YL, Zhang Y, Thomas D, Butcher R, Zhang Y, Cummins MR Tags: Am J Crit Care Source Type: research

Meaning of Intracranial Pressure-to-Blood Pressure Fisher-Transformed Pearson Correlation–Derived Optimal Cerebral Perfusion Pressure: Testing Empiric Utility in a Mechanistic Model
Conclusions: These mechanistic simulations provide insight into the empiric basis of optimal cerebral perfusion pressure and the significance of PRx and ΔCPP. PRx and optimal cerebral perfusion pressure deviations do not directly reflect changes in cerebral autoregulation but are, in general, related to the presence of complex states involving well-described clinical progressions with raised intracranial pressure.
Source: Critical Care Medicine - November 17, 2018 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Role of ECMO in life threatening intoxication
Publication date: Available online 21 December 2018Source: The Egyptian Journal of Critical Care MedicineAuthor(s): Vivek Gupta, Rajiv Gupta, Gurpreet S. WanderAbstractAcute severe poisoning may lead to life threatening situation or death due to cardiovascular dysfunction or stunning, arrhythmia or cardiogenic shock. These substances include medications, substances used for addiction, house hold chemicals, industrial, plants and animal or vegetable toxicants. The poison profile varies in different parts of world; drugs with cardiotoxic potential are the common poisoning substances while pesticides and other house hold toxi...
Source: The Egyptian Journal of Critical Care Medicine - December 22, 2018 Category: Intensive Care Source Type: research

Renin as a Marker of Tissue-Perfusion and Prognosis in Critically Ill Patients*
Objectives: To characterize renin in critically ill patients. Renin is fundamental to circulatory homeostasis and could be a useful marker of tissue-perfusion. However, diurnal variation, continuous renal replacement therapy and drug-interference could confound its use in critical care practice. Design: Prospective observational study. Setting: Single-center, mixed medical-surgical ICU in Europe. Patients: Patients over 18 years old with a baseline estimated glomerular filtration rate greater than 30 mL/min/1.73 m2 and anticipated ICU stay greater than 24 hours. Informed consent was obtained from the patient o...
Source: Critical Care Medicine - January 17, 2019 Category: Emergency Medicine Tags: Feature Articles Source Type: research

Intracranial Hypertension and Cerebral Perfusion Pressure Insults in Adult Hypertensive Intraventricular Hemorrhage: Occurrence and Associations With Outcome
Conclusions: Elevated intracranial pressure and inadequate cerebral perfusion pressure are not infrequent during extraventricular drainage for severe intraventricular hemorrhage, and level and duration predict higher short-term mortality and long-term mortality. Burden of low cerebral perfusion pressure was also associated with poor short- and long-term outcomes and may be more significant than intracranial pressure. Adverse consequences of intracranial pressure-time burden and cerebral perfusion pressure-time burden should be tested prospectively as potential thresholds for therapeutic intervention.
Source: Critical Care Medicine - July 13, 2019 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research

Brain Hypoxia Secondary to Diffusion Limitation in Hypoxic Ischemic Brain Injury Postcardiac Arrest
Objectives: We sought to characterize 1) the difference in the diffusion gradient of cellular oxygen delivery and 2) the presence of diffusion limitation physiology in hypoxic-ischemic brain injury patients with brain hypoxia, as defined by parenchymal brain tissue oxygen tension less than 20 mm Hg versus normoxia (brain tissue oxygen tension> 20 mm Hg). Design: Post hoc subanalysis of a prospective study in hypoxic-ischemic brain injury patients dichotomized into those with brain hypoxia versus normoxia. Setting: Quaternary ICU. Patients: Fourteen adult hypoxic-ischemic brain injury patients after cardiac arres...
Source: Critical Care Medicine - February 15, 2020 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research

Critical care management of severe head injury
Abstract: Severe traumatic brain injury (TBI) is a significant cause of morbidity and mortality. The intensive care management of TBI requires a coordinated and comprehensive approach to treatment, including strategies to prevent secondary brain injury by avoidance of systemic physiological disturbances, such as hypotension, hypoxaemia, hypoglycaemia, hyperglycaemia and hyperthermia, and maintenance of adequate cerebral perfusion and oxygenation. There have been marked improvements in the management of patients with severe TBI over the last two decades, and treatment advances in the pre-hospital setting and emergency depar...
Source: Anaesthesia and intensive care medicine - April 1, 2014 Category: Anesthesiology Authors: Martin Smith Tags: Neurosurgical anaesthesia Source Type: research

SCCM Pod-274 Tissue Oxygen Saturation and Finger Perfusion Index in Central Hypovolemia: Influence of Pain
Ludwig Lin, MD, speaks with Lars O. Hoiseth, MD.
Source: SCCM PodCast - iCritical Care - May 14, 2015 Category: Intensive Care Authors: The Society of Critical Care Medicine (SCCM) Tags: Medicine Source Type: podcasts

Prone Position in Acute Respiratory Distress Syndrome: Rationale, Indications and Limits.
Abstract In the prone position, CT-scan densities redistribute from dorsal to ventral as the dorsal region tends to re-expand while the ventral zone tends to collapse. Although gravitational influence is similar in both positions, dorsal recruitment usually prevails over ventral de-recruitment, due to the need for the lung and its confining chest wall to conform to the same volume. The final result of proning is that the overall lung inflation is more homogeneous from dorsal to ventral than in the supine position with more homogeneously distributed stress and strain. As the distribution of perfusion remains nearly...
Source: American Journal of Respiratory and Critical Care Medicine - October 17, 2013 Category: Respiratory Medicine Authors: Gattinoni L, Taccone P, Carlesso E, Marini JJ Tags: Am J Respir Crit Care Med Source Type: research

Segmental Hyperperfusion in Lobar Pneumonia Visualized with Respiratory-gated Four-Dimensional Pulmonary Perfusion Positron Emission Tomography-Computed Tomography.
PMID: 24381992 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - January 1, 2014 Category: Respiratory Medicine Authors: Hofman MS, Callahan J, Eu P, Hicks RJ Tags: Am J Respir Crit Care Med Source Type: research