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Associations Between the Use of Critical Care Procedures and Change in Functional Status at Discharge
Quality improvement initiatives in intensive care units (ICUs) have increased survival rates. Changes in functional status following ICU care have been studied, but results are inconclusive because of insufficient consideration of the combinations of critical care procedures used. Using the Japanese administrative database including the Barthel Index (BI) at admission and discharge, we measured the changes in functional status among the adult patients and determined whether longer ICU stay or use of various critical care procedures was associated with functional deterioration. Of the 12 502 528 patients admitted ...
Source: Journal of Intensive Care Medicine - August 30, 2013 Category: Intensive Care Authors: Kuwabara, K., Matsuda, S., Fushimi, K., Ishikawa, K. B., Horiguchi, H., Fujimori, K. Tags: Review of a Large Clinical Series Source Type: research

Applications of the international scoring system for Disseminated Intravascular Coagulopathy (DIC) and its interaction with Sequential Organ Failure Assessment Score (SOFA) in prediction of prognosis and final outcome in ICU
Conclusion A significant correlation exists between SOFA and DIC scores together in critically ill patients with APACHE II score ⩾25 as regards MODS and mortality. The combination of DIC and SOFA scores highly improves the prognostic performance of either score alone. It’s recommended to combine these scores together for better mortality prediction.
Source: The Egyptian Journal of Critical Care Medicine - November 6, 2014 Category: Intensive Care Source Type: research

Elizabethkingia meningoseptica : Emerging nosocomial pathogen in bedside hemodialysis patients
Conclusion: E. meningoseptica is emerging as a nosocomial pathogen among patients on hemodialysis. Its unusual resistance pattern coupled with inherent resistance to colistin makes this organism difficult to treat unless susceptibility patterns are available. Isolation of this organism in handwash sink and water is a significant finding as they have been reported to survive in chlorinated water. Disinfecting the sinks and using filtered water for hand washing in critical areas may help in preventing infections with this organism.
Source: Indian Journal of Critical Care Medicine - October 24, 2013 Category: Intensive Care Authors: MS RatnamaniRatna Rao Source Type: research

Indications and outcomes in children receiving renal replacement therapy in pediatric intensive care
Conclusions: Hemodynamic instability and multiorgan dysfunction syndrome are the most common clinical conditions associated with acute kidney injury in our population. In the population studied, the mortality was lower than previously reported in children and much lower than in the adult population.
Source: Journal of Critical Care - November 18, 2013 Category: Intensive Care Authors: Erin D. Boschee, Dominic A. Cave, Daniel Garros, Laurance Lequier, Donald A. Granoski, Gonzalo Garcia Guerra, Lindsay M. Ryerson Tags: Outcomes Source Type: research

Reversal of severe lactic acidosis with thiamine in a renal allograft recipient
K Nanda Kumar, Veena R Shah, Beena K Parikh, Sumedha SondeIndian Journal of Critical Care Medicine 2015 19(7):425-428A 48-year-old female patient with end-stage renal failure developed unexplained severe lactic acidosis (LA) associated with hyperglycemia during robotic-assisted laparoscopic renal transplantation. Initial treatment with sodium bicarbonate and insulin infusion were ineffective in treating acidemia. Postoperatively, intravenous administration of thiamine resulted in rapid improvement of LA and blood sugar levels. Uremia and chronic hemodialysis might be the causes behind the quantitative/qualitative deficienc...
Source: Indian Journal of Critical Care Medicine - July 8, 2015 Category: Intensive Care Authors: K Nanda KumarVeena R ShahBeena K ParikhSumedha Sonde Source Type: research

Assessment of accuracy of Cockcroft-Gault and MDRD formulae in critically ill Indian patients
Conclusion: We conclude that CG and MDRD formulae have a strong correlation with measured GFR but are not a reliable measure and overestimate GFR in critically ill Indian patients.
Source: Indian Journal of Critical Care Medicine - July 9, 2013 Category: Intensive Care Authors: Mohit KharbandaArghya MajumdarS BasuSubhash Todi Source Type: research

Glyphosate surfactant herbicide poisoning and management
Kranthi Mahendrakar, Pradeep M. Venkategowda, S. Manimala Rao, Dnyaneshwar P. MutkuleIndian Journal of Critical Care Medicine 2014 18(5):328-330Glyphosate is a widely used herbicide in agriculture, forestry, industrial weed control and aquatic environments. Glyphosate potential as herbicide was first reported in 1971. It is a non-selective herbicide. It can cause a wide range of clinical manifestations in human beings like skin and throat irritation to hypotension, oliguria and death. We are reporting a case of a 35-year-old male patient who was admitted to our tertiary care hospital following intentional ingestion of arou...
Source: Indian Journal of Critical Care Medicine - May 14, 2014 Category: Intensive Care Authors: Kranthi MahendrakarPradeep M. VenkategowdaS. Manimala RaoDnyaneshwar P. Mutkule Source Type: research

Severe valproate induced hyperammonemic encephalopathy successfully managed with peritoneal dialysis
We report such a case of VIH and life-threatening VHE in a postoperative neurosurgical patient that was managed successfully with peritoneal dialysis.
Source: Indian Journal of Critical Care Medicine - July 5, 2014 Category: Intensive Care Authors: Amandeep KumarAshish SuriBhawani S Sharma Source Type: research

Acute kidney injury and rhabdomyolysis due to multiple wasp stings
We report a case of acute kidney injury and rhabdomyolysis secondary to multiple wasp stings. A 55-year-old farmer developed multi organ dysfunction with acute kidney injury and rhabdomyolysis 3 days after he had sustained multiple wasp stings. The etiology of acute kidney injury is probably both rhabdomyolysis and acute tubular necrosis. He improved completely after hemodialysis and intensive care.
Source: Indian Journal of Critical Care Medicine - July 5, 2014 Category: Intensive Care Authors: Hemachandar Radhakrishnan Source Type: research

Candida glabrata candidemia: An emerging threat in critically ill patients
Conclusion: Candida glabrata was the 3 rd most common Candida causing candidemia in our ICUs with a incidence of 0.21/1000 ICU admissions. The outcome of ICU acquired C. glabrata candidemia was poor with 30 days mortality rate of 53.8%. Renal failure requiring hemodialysis was the only risk factor associated with mortality. Further studies are required to identify the other risk factors associated with mortality in C. glabrata candidemia.
Source: Indian Journal of Critical Care Medicine - March 5, 2015 Category: Intensive Care Authors: Ashish GuptaAnu GuptaAmit Varma Source Type: research

Extracorporeal treatment with high-volume continuous venovenous hemodiafiltration and charcoal-based sorbent hemoperfusion for severe metformin-associated lactic acidosis
We present a case of a 49-year-old female with an alleged history of ingestion of approximately 100 tablets of metformin (850 mg each). Investigations revealed severe lactic acidosis with lactate levels of 13.5 mmol/L and pH of 7.17. This indicates severe toxicity and is associated with a high mortality. Charcoal-based sorbent hemoperfusion was done as a desperate effort, as patient continued to deteriorate despite supportive care and high-volume continuous venovenous hemodiafiltration. The patient survived despite metformin-associated lactic acidosis related to severe metformin toxicity.
Source: Indian Journal of Critical Care Medicine - May 9, 2016 Category: Intensive Care Authors: Suneel Kumar GargOmender SinghDesh DeepakAkhilesh SinghRohit YadavKirti Vashist Source Type: research

A pilot randomized controlled trial of comparison between extended daily hemodialysis and continuous veno-venous hemodialysis in patients of acute kidney injury with septic shock
Conclusion: SLED is a viable modality of renal replacement therapy in patients with septic shock as the hemodynamic effects are similar to CRRT.
Source: Indian Journal of Critical Care Medicine - May 16, 2017 Category: Intensive Care Authors: Shakti Bedanta Mishra Afzal Azim Narayan Prasad Ratendra Kumar Singh Banani Poddar Mohan Gurjar Arvind Kumar Baronia Source Type: research

A study of continuous renal replacement therapy and acute peritoneal dialysis in hemodynamic unstable patients
Conclusion: This study showing comparable survival outcome in acute PD and CRRT gives evidence that either of the modalities can be adopted in hemodynamically unstable patients requiring RRT depending on the resources available.
Source: Indian Journal of Critical Care Medicine - June 15, 2017 Category: Intensive Care Authors: Ajay Jaryal Sanjay Vikrant Source Type: research

Complication and Failures of Central Vascular Access Device in Adult Critical Care Settings*
Conclusions: Central venous access device complications and device failure is a prevalent and significant problem in the adult ICU, leading to substantial patient harm and increased healthcare costs. The high proportion of central venous access devices removed due to suspicion of infection, despite low overall central line-associated bloodstream infection and catheter-related bloodstream infection rates, indicates a need for robust practice guidelines to inform decision-making surrounding removal of central venous access devices suspected of infection.
Source: Critical Care Medicine - November 17, 2018 Category: Emergency Medicine Tags: Review Articles Source Type: research

Hyperammonemic coma in a post-partum patient with undiagnosed urea cycle defect
Sananta Kumar Dash, Munish Chauhan, Vishakh Varma, Rakesh Sharma, Sudha Kansal, Rajesh ChawlaIndian Journal of Critical Care Medicine 2013 17(2):107-110Urea cycle disorders (UCD) are common during neonatal period, and it is rarely reported in adults. We are reporting a patient presenting with post-partum neuropsychiatric symptoms rapidly progressing to coma. Markedly raised serum ammonia level on presentation with an initial normal magnetic resonance imaging (MRI) of brain and normal liver function tests led to the suspicion of UCD, which was confirmed on the basis of urine orotic acid and elevated serum amino acid levels....
Source: Indian Journal of Critical Care Medicine - July 9, 2013 Category: Intensive Care Authors: Sananta Kumar DashMunish ChauhanVishakh VarmaRakesh SharmaSudha KansalRajesh Chawla Source Type: research