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Effects of public health emergencies of international concern on disease control: a systematic review
CONCLUSIONS: Socioeconomic inequity is a determinant of the effects of public health emergencies of international concern within affected populations. The diversion of resources and attention from health authorities disproportionately affects vulnerable populations and can lead, over time, to a weakening of health systems. The analysis of the effects of public health emergencies is important for the development of new protocols that can better respond to future crises.PMID:37089787 | PMC:PMC10120386 | DOI:10.26633/RPSP.2023.74
Source: Pan American Journal of Public Health - April 24, 2023 Category: International Medicine & Public Health Authors: Giovanna Rotondo de Ara újo Pedro A S V de Castro Isabela R Ávila Juliana Maria T Bezerra David S Barbosa Source Type: research
Advances in HIV Vaccine Research Show Promise for Prevention Advances in HIV Vaccine Research Show Promise for Prevention
In their search for an effective HIV vaccine, researchers have explored several platforms and targets to generate a robust immune response.Medscape Medical News
Source: Medscape Internal Medicine Headlines - June 8, 2023 Category: Internal Medicine Tags: HIV/AIDS News Source Type: news
An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain
Cell Rep. 2020 Oct 20;33(3):108274. doi: 10.1016/j.celrep.2020.108274. Epub 2020 Sep 29.ABSTRACTIGHV3-53-encoded neutralizing antibodies are commonly elicited during SARS-CoV-2 infection and target the receptor-binding domain (RBD) of the spike (S) protein. Such IGHV3-53 antibodies generally have a short CDR H3 because of structural constraints in binding the RBD (mode A). However, a small subset of IGHV3-53 antibodies to the RBD contain a longer CDR H3. Crystal structures of two IGHV3-53 neutralizing antibodies here demonstrate that a longer CDR H3 can be accommodated in a different binding mode (mode B). These two classe...
Source: IAVI Rep - October 7, 2020 Category: Infectious Diseases Authors: Nicholas C Wu Meng Yuan Hejun Liu Chang-Chun D Lee Xueyong Zhu Sandhya Bangaru Jonathan L Torres Tom G Caniels Philip J M Brouwer Marit J van Gils Rogier W Sanders Andrew B Ward Ian A Wilson Source Type: research
