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A mini-review on ELISA-Based Diagnosis of Schistosomiasis
CONCLUSION: schistosomiasis is considered the most important helminthic disease in worldwide. therefore, it is important to of searching for and develops diagnostic methods based on serology to reduce morbidity and mortality caused by the disease.PMID:37143281 | DOI:10.2174/1566524023666230504140828
Source: Molecular Medicine - May 5, 2023 Category: Molecular Biology Authors: Michelli Dos Santos Mariana Teixeira de Faria Jonatas Oliveira da Silva Isadora Braga Gandra Anna Julia Ribeiro Kamila Alves Silva Lais Moreira Nogueira Juliana Martins Machado Reysla Maria da Silveira Mariano Ana Alice Maia Gon çalves Fernanda Ludolf Ma Source Type: research
Type II CRISPR-Cas System Nucleases: A Pipeline for Prediction and In Vitro Characterization
Mol Biol (Mosk). 2023 May-Jun;57(3):546-560.ABSTRACTThe use of CRISPR-Cas bacterial adaptive immunity system components for targeted DNA changes has opened broad prospects for programmable genome editing of higher organisms. The most widely used gene editors are based on the Cas9 effectors of the type II CRISPR-Cas systems. In complex with guide RNAs, Cas9 proteins are able to directionally introduce double-stranded breaks into DNA regions that are complementary to guide RNA sequences. Despite the wide range of characterized Cas9s, the search for new Cas9 variants remains an important task, since the available Cas9 editors...
Source: Molekuliarnaia Biologiia - June 16, 2023 Category: Molecular Biology Authors: A A Vasileva S A Aliukas P A Selkova A N Arseniev V E Chernova O S Musharova E I Klimuk M A Khodorkovskii K V Severinov Source Type: research
