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Proton Beam Therapy for Cancer in Children and Adults: A Health Technology Assessment
CONCLUSIONS: Proton beam therapy may be as effective as conventional radiation therapy, and it may cause fewer side effects, especially for children with brain tumours and for adults with certain types of cancer. Based on published economic evidence, proton beam therapy is likely cost-effective compared with photon therapy in children with medulloblastoma, but cost-effectiveness is unclear in children and adults with other clinical indications. We estimate that publicly funding a proton beam therapy centre in Ontario would result in additional costs of $124.8 million over the next 5 years, but with a six- to seven-fold red...
Source: Ontario Health Technology Assessment Series - May 31, 2021 Category: General Medicine Authors: Ontario Health (Quality) Source Type: research

The role of postoperative radiotherapy in eccrine porocarcinoma: a multidisciplinary systematic review
CONCLUSIONS: Adjuvant radiotherapy after surgical removal of EPC could be considered in cases with positive or close margins and in cases with unfavorable histological features. In view of limited literature data and the rarity of EPC the best treatment sequence should always be discussed within the frame of a multidisciplinary setting.ADVANCES IN KNOWLEDGE: adjuvant radiotherapy after surgical removal of EPC could be considered in cases with positive or close margins and in cases with unfavorable histological features.PMID:35302218 | DOI:10.26355/eurrev_202203_28238
Source: European Review for Medical and Pharmacological Sciences - March 18, 2022 Category: Drugs & Pharmacology Authors: B Fionda A Di Stefani V Lancellotta S Gentileschi A A Caretto C Cas à F Federico A Rembielak E Rossi A G Morganti G Schinzari K Peris L Tagliaferri Source Type: research