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Mg-Zn-Ca Alloy (ZX00) Screws Are Resorbed at a Mean of 2.5 Years After Medial Malleolar Fracture Fixation: Follow-up of a First-in-humans Application and Insights From a Sheep Model
CONCLUSION: In this sheep model, Mg-alloy (ZX00) screws showed a resorption to one-third of the original volume after 25 months, without eliciting adverse immunologic reactions, supporting biocompatibility during this period. Mg-alloy (ZX00) implants were not detectable on radiographs after a mean of 2.5 years, suggesting full resorption, but further studies are needed to assess environmental changes regarding bone quality at the implantation site after implant resorption.CLINICAL RELEVANCE: The study demonstrated successful healing of medial malleolar fractures using bioresorbable Mg-alloy screws without clinical complica...
Source: Clinical Orthopaedics and Related Research - August 21, 2023 Category: Orthopaedics Authors: Viktor Labmayr Omer Suljevic Nicole Gabriele Sommer Uwe Yacine Schwarze Romy Linda Marek Iva Brcic Ines Foessl Andreas Leithner Franz Josef Seibert Valentin Herber Patrick Lukas Holweg Source Type: research

Graphene Oxide-based Endodontic Sealer: An in Vitro Study
Acta Med Okayama. 2022 Dec;76(6):715-721. doi: 10.18926/AMO/64122.ABSTRACTThe failure of endodontic treatment is directly associated with microbial infection in the root canal or periapical areas. An endodontic sealer that is both bactericidal and biocompatible is essential for the success of root canal treatments. This is one of the vital issues yet to be solved in clinical dental practice. This in vitro study assessed the effectiveness of graphene oxide (GO) composites GO-CaF2 and GO-Ag-CaF2 as endodontic sealer materials. Dentin slices were coated with either the GO-based composites or commonly used root canal sealers (...
Source: Acta Med Okayama - December 22, 2022 Category: Universities & Medical Training Authors: Mohammed Zahedul Islam Nizami Melahat Gorduysus Yuki Shinoda-Ito Tadashi Yamamoto Yuta Nishina Shogo Takashiba Zulema Arias Source Type: research

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