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Total 77 results found since Jan 2013.
Established and Emerging Lipid-Lowering Drugs for Primary and Secondary Cardiovascular Prevention
This article reviews established and emerging lipid-lowering drugs regarding their mechanism of action, development stage, ongoing clinical trials, side effects, effect on blood lipids and reduction in cardiovascular morbidity and mortality. We conducted a keyword search to identify studies on established and emerging lipid modifying drugs. Results were summarized in a narrative overview. Established pharmaceutical treatment options include the Niemann-Pick-C1 like-1 protein (NPC1L1) inhibitor ezetimibe, the protein convertase subtilisin-kexin type 9 (PCSK9) inhibitors alirocumab and evolocumab, fibrates as peroxisome prol...
Source: Cancer Control - July 24, 2023 Category: Cancer & Oncology Authors: Daniel Tobias Michaeli Julia Caroline Michaeli Sebastian Albers Tobias Boch Thomas Michaeli Source Type: research
Indications for omega-3 fatty acid supplementation in prevention of cardiovascular disease: From fish to pharmaceuticals
CONCLUSION: All guidelines recommend at least 2 servings of oily fish per week, although benefit from O3FAs is mostly seen in secondary prevention. Fish oil and combination preparations of eicosapentaenoic acid and docosahexaenoic acid have failed to show benefit at any dose at any level of prevention in patients who are appropriately prescribed statins. High-dose eicosapentaenoic acid shows substantial benefit in selected patients taking statins who have high triglyceride levels.PMID:37452000 | DOI:10.46747/cfp.6907459
Source: Canadian Family Physician Medecin de Famille Canadien - July 14, 2023 Category: Primary Care Authors: N John Bosomworth Source Type: research
