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Total 5 results found since Jan 2013.
Azadirachta indica A. Juss bark extract and its Nimbin isomers restrict β-coronaviral infection and replication
Virology. 2022 Feb 15;569:13-28. doi: 10.1016/j.virol.2022.01.002. Online ahead of print.ABSTRACTEmerging mutations in the SARS-CoV-2 genome pose a challenge for vaccine development and antiviral therapy. The antiviral efficacy of Azadirachta indica bark extract (NBE) was assessed against SARS-CoV-2 and m-CoV-RSA59 infection. Effects of in vivo intranasal or oral NBE administration on viral load, inflammatory response, and histopathological changes were assessed in m-CoV-RSA59-infection. NBE administered inhibits SARS-CoV-2 and m-CoV-RSA59 infection and replication in vitro, reducing Envelope and Nucleocapsid gene expressi...
Source: Virology - February 26, 2022 Category: Virology Authors: Lucky Sarkar Lauren Oko Soham Gupta Andrew N Bubak Bishnu Das Parna Gupta Abass Alao Safiriyu Chirag Singhal Ujjwal Neogi David Bloom Arup Banerjee Ravi Mahalingam Randall J Cohrs Michael Koval Kenneth S Shindler Debnath Pal Maria Nagel Jayasri Das Sarma Source Type: research
