Filtered By:
Specialty: Molecular Biology
Therapy: Radiation Therapy
This page shows you your search results in order of date.
Order by Relevance | Date
Total 182 results found since Jan 2013.
ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells
Curr Issues Mol Biol. 2023 Jul 27;45(8):6262-6271. doi: 10.3390/cimb45080394.ABSTRACTRadiation therapy is commonly used to treat head and neck squamous cell carcinoma (HNSCC); however, recurrence results from the development of radioresistant cancer cells. Therefore, it is necessary to identify the underlying mechanisms of radioresistance in HNSCC. Previously, we showed that the inhibition of karyopherin-β1 (KPNB1), a factor in the nuclear transport system, enhances radiation-induced cytotoxicity, specifically in HNSCC cells, and decreases the localization of SCC-specific transcription factor ΔNp63. This suggests that Δ...
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Kota Sato Hironori Yoshino Yoshiaki Sato Manabu Nakano Eichi Tsuruga Source Type: research
