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Statins Use in Elderly Patients.
Abstract The risk of cardiovascular disease in elderly is significantly higher than in young subjects; paradoxically some treatments that have proven their efficacy in reducing cardiovascular risk are often under prescribed in this age group. The benefits of statins in secondary cardiovascular prevention are well established in patients <80 years. In primary prevention, these drugs reduce the risk of myocardial infarction and stroke, but their effects on cardiovascular mortality remain uncertain. In very elderly patients, there are no randomized trials relative to the impact of statins on morbi-mortality in pri...
Source: Therapie - November 2, 2015 Category: Psychiatry & Psychology Authors: Hammami R, Jdidi J, Triki F, Hammami B, Abid L, Ksouda K, Hammami S, Abid D, Hentati M, Kammoun S Tags: Therapie Source Type: research

A historical cohort study to investigation of statins safety in COVID-19 hospitalized patients
CONCLUSION: The use of statins did not seem to change outcomes in COVID19.PMID:34776254 | DOI:10.1016/j.therap.2021.10.006
Source: Therapie - November 15, 2021 Category: Psychiatry & Psychology Authors: Saeed Nateghi Mohammad Mahmoudi Gomari Hadiseh Hosamirudsari Behnam Behnoush Asma Razmjoofard Goli Azimi Shokooh Ordookhani Ali Jafarpour Neda Faraji Source Type: research

Does aspirin have a place in primary cardiovascular prevention by the polypill  ? Simulation study on a realistic virtual population
CONCLUSION: Until proven otherwise, aspirin has only a limited place in individuals between 35 and 65 years without a cardiovascular history. We showed how simulating therapeutic strategies on a realistic virtual population could be used for best applying available evidence.PMID:36841655 | DOI:10.1016/j.therap.2023.01.011
Source: Therapie - February 25, 2023 Category: Psychiatry & Psychology Authors: Mor Fall Guillaume Grenet Hai-Ha Le Behrouz Kassa ï Jean-Christophe Lega R émy Boussageon Sabine Mainbourg Ivanny Marchant Johanne Gafsi Amadou Moctar Dieye Fran çois Gueyffier Source Type: research