Filtered By:
Specialty: Neurosurgery
Therapy: Statin Therapy

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 28 results found since Jan 2013.

Long term risk of stroke versus acute coronary events after tia and stroke: a population-based study
Conclusion The long–term risk of major vascular events after TIA and stroke remains substantial, but about 70% of fatal and non–fatal events are now accounted for by recurrent stroke rather than acute coronary events.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Paul, N. L., Mehta, Z., Silver, L., Geraghty, O. C., Rothwell, P. M. Tags: Stroke, Ischaemic heart disease Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

P-016 Relationship between stroke recurrence, infarct pattern, and vascular distribution in patients with symptomatic intracranial stenosis
Conclusion We determined that basilar artery stenosis was most likely to present as a perforator stroke. As expected, patients discharged with suboptimal medical therapy were twice as likely to have a recurrent stroke (29% versus 13%). Among patients with optimal medical therapy, no recurrent strokes were seen in patients with embolic infarct pattern, while 57% recurrence rate was seen in patients with a watershed infarct pattern, suggesting that an embolic infarct pattern on initial presentation is possibly related to underlying plaque instability that is modifiable with optimal medical therapy. On the other hand, initial...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Raghuram, K., Kohlnhofer, J., Durgam, A. Tags: Oral Poster Abstracts Source Type: research

Prediction of death after endovascular thrombectomy in the extended window: a secondary analysis of DEFUSE 3 "
Conclusions Despite selective inclusion criteria and overwhelming benefit for EVT, a substantial number of EVT patients in DEFUSE 3 died. The preprocedural variables age, NIHSS, wake-up stroke, and diabetes may predict this risk. Our predictive score provides a basis for future research to determine which factors influence lethal outcome after EVT.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Taussky, P., Agnoletto, G., Grandhi, R., Alexander, M. D., Wong, K.-H., Albers, G. W., de Havenon, A. Tags: Ischemic stroke Source Type: research

E-238 A jellyfish in the net - a case of recurrent stroke caused by a mobile floating carotid intimal plaque
ConclusionMobile floating carotid intimal plaque is a rare cause of embolic events. While the carotid stenosis is not severe, a meticulous examination of carotid doppler sonography needed to find any embolic source.Disclosures S. Lee: None. Y. Won: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lee, S., Won, Y. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Secondary prevention in patients with vascular disease. A population based study on the underuse of recommended medications
Conclusions Our findings underline the fact that the underuse of secondary preventive therapies is common in patients with recurrent vascular events, especially those with previous cerebral ischaemia. This underuse could be targeted to reduce recurrent vascular events.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Bejot, Y., Zeller, M., Lorgis, L., Troisgros, O., Aboa-Eboule, C., Osseby, G.-V., Giroud, M., Cottin, Y. Tags: Stroke, Ischaemic heart disease Cerebrovascular disease Source Type: research

Lesion location, stability, and pretreatment management: factors affecting outcomes of endovascular treatment for vertebrobasilar atherosclerosis
Conclusions Endovascular treatment of symptomatic vertebrobasilar atherosclerosis can be performed safely and with good outcomes. Technical results were better for those with extracranial disease while clinical outcomes were more favorable in those patients with non-progressive symptoms in the subacute period and those receiving statin therapy.
Source: Journal of NeuroInterventional Surgery - April 13, 2016 Category: Neurosurgery Authors: Alexander, M. D., Rebhun, J. M., Hetts, S. W., Kim, A. S., Nelson, J., Kim, H., Amans, M. R., Settecase, F., Dowd, C. F., Halbach, V. V., Higashida, R. T., Cooke, D. L. Tags: Ischemic stroke Source Type: research

Dream a little dream: an update on genetics guided therapy for stroke in australia
Conclusions The current evidence does not support pharmacogenetic guided therapy in stroke in Australia. However, a one-size fits all approach does not work and there is a definite dearth of Australian based pharmacogenetic research, which must be addressed.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Johnson, K., Haque, S., Shaffi, M. Tags: Abstracts Source Type: research

Case presentation: the dancing man from sierra leone
Discussion Making this diagnosis is challenging, as brain imaging often shows non specific changes and blood results are usually normal. CSF may reveal raised proteins and WBCs. A high index of suspicion is required to arrange a brain biopsy as this confirms the diagnosis.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Al-Rifai, M. S., Salek-Haddadi, A. Tags: Immunology (including allergy), Neuroimaging, Stroke, Radiology, Drugs: musculoskeletal and joint diseases, Vascularitis, Surgical diagnostic tests ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Intracranial hemorrhage in large vessel occlusion patients receiving endovascular thrombectomy with or without intravenous alteplase: a secondary analysis of the DIRECT-MT trial
Conclusions Our data showed that in the DIRECT-MT trial, alteplase did not increase overall ICH for large vessel occlusion patients treated with thrombectomy, but it increased the parenchymal hematoma rate.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Hu, X., Zhou, Y., Ospel, J., Yao, F., Liu, Y., Wang, H., Li, B., Hui, P., Yang, P., Zhang, Y., Zhang, L., Li, Z., Xing, P., Shi, H., Han, H., Wang, S., Fang, Q., Liu, J., for the Direct-MT investigators Tags: Open access, Ischemic stroke Source Type: research

E-027 Intracranial Stenting for Patients whom have Failed Medical Therapy: A Single Center Sub-analysis of the VISSIT Trial
Conclusion In this small subgroup of the VISSIT Trial, Intracranial stenting is superior to medical therapy alone in patients whom have previously failed medical therapy. Future studies should focus on patient selection within this high-risk patient population. Disclosures B. Woodward: 2; C; Codman Neurovascular.
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Woodward, B. Tags: Electronic poster abstracts Source Type: research

E-107 Carotid artery stenting in patients with symptomatic non-stenotic carotid artery disease - a case series
ConclusionsIn this case series performed over a 10-year period at a high-volume stroke center we show that CAS is safe and efficient in patients with SyNC. Previous studies have established safety and effectiveness of CES in patients presenting with SyNC, however there is a paucity of reports in the literature regarding the effect of CAS in this patient population. Recent guidelines have brought specific attention to high-risk plaque characteristics which suggest that plaque instability plays a major role in the onset of ischemic events, regardless of lumen narrowing. Advanced imaging techniques, such as Optical Coherence ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Nedelcu, S., Kuhn, A., Singh, J., Puri, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Assessment of the MRI and Behavioral Test Results in Focal Cerebral Ischemia Reperfusion Model in Rat after Separate and Combined Use of Mouse-Derived Neural Progenitor Cells, Human-Derived Neural Progenitor Cells and Atorvastatin.
CONCLUSION: Both hNPC and mNPC treatments significantly improved functional outcome, and reduced infarct area rate after stroke. Atorvastatin enhanced the therapeutic potency of NPCs, including neurological improvement. PMID: 29204982 [PubMed - as supplied by publisher]
Source: Turkish Neurosurgery - November 1, 2017 Category: Neurosurgery Authors: Tahta A, Izgi N, Onder TB, Erdag E, Aras Y, Genc C Tags: Turk Neurosurg Source Type: research

Assessment of the MRI and Behavioral Test Results in a Focal Cerebral Ischemia-Reperfusion Model in the Rat after Separate and Combined Use of Mouse-Derived Neural Progenitor Cells, Human-Derived Neural Progenitor Cells and Atorvastatin.
CONCLUSION: Both hNPC and mNPC treatments significantly improved functional outcome, and reduced infarct area ratio after stroke. Atorvastatin enhanced the therapeutic potency of NPCs, including neurological improvement. PMID: 30192361 [PubMed - in process]
Source: Turkish Neurosurgery - September 9, 2018 Category: Neurosurgery Authors: Tahta A, Izgi N, Bagci-Onder T, Erdag E, Aras Y, Genc C Tags: Turk Neurosurg Source Type: research

E-113 Lower low-density lipoprotein level increases the risk of delayed parenchymal hematoma following endovascular thrombectomy
ConclusionLDL level <50 mg/dL independently predicted delayed PH following thrombectomy and LDL >100 was shown to be a protective factor, irrespective of statin use. Further study is needed to explore the underlying mechanism and identify the strategies to prevent post-thrombectomy delayed PH among patients with low LDL levels.Disclosures S. Ahn: None. S. Roth: None. J. Jo: None. Y. Ko: None. N. Mummareddy: None. M. Fusco: None. R. Chitale: None. M. Froehler: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ahn, S., Roth, S., Jo, J., Ko, Y., Mummareddy, N., Fusco, M., Chitale, R., Froehler, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Potential role of statins in the intracerebral hemorrhage and subarachnoid hemorrhage
Publication date: September–October 2015 Source:Neurologia i Neurochirurgia Polska, Volume 49, Issue 5 Author(s): Dariusz Kotlęga, Monika Gołąb-Janowska, Marta Masztalewicz, Sylwester Ciećwież, Przemysław Nowacki Statins are used in primary and secondary prevention of cardiovascular episodes. Most of recent studies regard ischemic stroke. There are more emerging results of studies suggesting usefulness of these drugs in the other types of stroke e.g. intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Searching for new methods of treatment is important, because both ICH and SAH lead to poor pro...
Source: Polish Journal of Neurology and Neurosurgery - January 19, 2016 Category: Neurosurgery Source Type: research