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Specialty: Neurosurgery

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Total 6508 results found since Jan 2013.

P014/130 Treatment of recurrent intracranial atherosclerotic disease-related stroke due to in-stent thrombosis with the CREDO(R) heal stent: A case report
ConclusionThis case highlights that re-stenting a recurrent ICAD-related stroke using the CREDO® heal stent is technically feasible, safe, and may improve clinical outcomes.Disclosure of InterestNothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Nguyen, A., Schulze-Zachau, V., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

Newly detected paroxysmal atrial fibrillation after tia and ischaemic stroke on cardiac monitoring: systematic review and meta-analysis in relation to duration of recording
Conclusion Cardiac monitoring after TIA or ischaemic stroke detects clinically important rates of pAF in studies of unselected populations, with high rates of subsequent anticoagulation. A monitoring period of 5–7 days appears to be adequate.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Yiin, G. S., Lovett, N. G., Rothwell, P. M. Tags: Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Constraint-induced aphasia therapy following sub-acute stroke: a single-blind, randomised clinical trial of a modified therapy schedule
Conclusions Both CIAT and conventional therapy performed with equal intensity are efficacious methods for patients with sub-acute aphasia. The modified CIAT schedule is practical in an everyday therapeutic setting. Our results indicate that a short-term intensive therapy schedule in the early aphasia stage leads to substantial improvements in language functions. Clinical Trial Registration Information Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01625676
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 10, 2013 Category: Neurosurgery Authors: Sickert, A., Anders, L.-C., Munte, T. F., Sailer, M. Tags: Stroke Cerebrovascular disease Source Type: research

Transcervical access in acute ischemic stroke
Conclusions Transcervical access for acute ischemic stroke leads to rapid and high quality recanalization. Future studies will focus on improved hemostasis and early identification of patients who would benefit the most from direct carotid access for acute stroke.
Source: Journal of NeuroInterventional Surgery - October 7, 2014 Category: Neurosurgery Authors: Jadhav, A. P., Ribo, M., Grandhi, R., Linares, G., Aghaebrahim, A., Jovin, T. G., Jankowitz, B. T. Tags: Ischemic stroke Source Type: research

P-019 Clinical Conviction: Selection Bias In Recent Endovascular Stroke Trials
Conclusions Endovascular trials excluded the majority of patients deemed suitable for ERT in routine practice. Competing interests from other trials as well as reluctance to randomise against EST limited enrollment. The population of patients enrolled in trials tended to present later, have more severe strokes, and suffer worsened outcomes. Conviction in the benefit of EST led to the treatment of patients most likely to benefit from EST outside of trials. As a result, recent EST trials may have not reflected the treatment population and outcomes of routine practice. Disclosures S. Sheth: None. J. Saver: None. R. Jahan: No...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Sheth, S., Saver, J., Jahan, R., Starkman, S., Duckwiler, G., Tateshima, S., Gonzalez, N., Liebeskind, D., Stroke Investigators, U. Tags: Oral poster abstracts Source Type: research

Primary manual aspiration thrombectomy (MAT) for acute ischemic stroke: safety, feasibility and outcomes in 112 consecutive patients
Conclusions Primary MAT is an alternative endovascular recanalization technique with reasonable first pass efficacy that will likely improve with technology and experience.
Source: Journal of NeuroInterventional Surgery - December 11, 2014 Category: Neurosurgery Authors: Jankowitz, B., Grandhi, R., Horev, A., Aghaebrahim, A., Jadhav, A., Linares, G., Jovin, T. Tags: Ischemic stroke Source Type: research

A meta-analysis of prospective randomized controlled trials evaluating endovascular therapies for acute ischemic stroke
Conclusions A meta-analysis of prospective RCTs comparing endovascular therapies with medical management demonstrates superior outcomes in patients randomized to endovascular therapy.
Source: Journal of NeuroInterventional Surgery - January 13, 2015 Category: Neurosurgery Authors: Fargen, K. M., Neal, D., Fiorella, D. J., Turk, A. S., Froehler, M., Mocco, J. Tags: Editor''s choice, Ischemic stroke Source Type: research

Endovascular treatment of tandem vascular occlusions in acute ischemic stroke
Conclusions Our study shows preliminary data from three centers on recanalization of tandem occlusions in patients presenting with AIS. There was a preference to revascularize the proximal occlusion using a stent followed by distal recanalization with mechanical thrombectomy, intra-arterial thrombolysis or a combination of these. This approach has low periprocedural complications and can achieve an excellent angiographic and clinical outcome.
Source: Journal of NeuroInterventional Surgery - February 12, 2015 Category: Neurosurgery Authors: Puri, A. S., Kuhn, A. L., Kwon, H.-J., Khan, M., Hou, S. Y., Lin, E., Chueh, J., van der Bom, I. M., Dabus, G., Linfante, I., Gounis, M. J., Wakhloo, A. K. Tags: Ischemic stroke Source Type: research

Carotid stenting and intracranial thrombectomy for treatment of acute stroke due to tandem occlusions with aggressive antiplatelet therapy may be associated with a high incidence of intracranial hemorrhage
Conclusions Primary stenting of the extracranial carotid artery combined with intracranial mechanical thrombectomy can be an effective treatment for tandem occlusions, can be performed with a high rate of technical success, and can achieve good clinical outcomes in selected patients. However, the incidence of SICH may be higher than in other patient populations and may be associated with the use of abciximab and advanced patient age.
Source: Journal of NeuroInterventional Surgery - February 12, 2015 Category: Neurosurgery Authors: Heck, D. V., Brown, M. D. Tags: Ischemic stroke Source Type: research

Incidence, predictors and clinical characteristics of orolingual angio-oedema complicating thrombolysis with tissue plasminogen activator for ischaemic stroke
Conclusions Angio-oedema occurs more frequently than previously reported and is associated with preceding ACE-I treatment. Angio-oedema may be delayed and progress to life-threatening airway compromise, which has implications for the assessment and delivery of thrombolysis.
Source: Journal of Neurology, Neurosurgery and Psychiatry - April 13, 2015 Category: Neurosurgery Authors: Hurford, R., Rezvani, S., Kreimei, M., Herbert, A., Vail, A., Parry-Jones, A. R., Douglass, C., Molloy, J., Alachkar, H., Tyrrell, P. J., Smith, C. J. Tags: Immunology (including allergy), Stroke, Radiology Cerebrovascular disease Source Type: research

What causes intracerebral bleeding after thrombolysis for acute ischaemic stroke? Recent insights into mechanisms and potential biomarkers
The overall population benefit of intravascular recombinant tissue plasminogen activator (rtPA) on functional outcome in ischaemic stroke is clear, but there are some treated patients who are harmed by early symptomatic intracranial haemorrhage (ICH). Although several clinical and radiological factors increase the risk of rtPA-related ICH, none of the currently available risk prediction tools are yet useful for practical clinical decision-making, probably reflecting our limited understanding of the underlying mechanisms. Finding new methods to identify patients at highest risk of rtPA-related ICH, or new measures to limit ...
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 13, 2015 Category: Neurosurgery Authors: Karaszewski, B., Houlden, H., Smith, E. E., Markus, H. S., Charidimou, A., Levi, C., Werring, D. J. Tags: Stroke Cerebrovascular disease Source Type: research

Network dysfunction in post-stroke aphasia
Recovery of language function after aphasic stroke is the product of activity in domain-general and domain-specific distributed brain networks. These may include left and right fronto-temporo-parietal, cingulo-opercular, and default mode networks. This functional MRI study investigated the effects of a previous left hemisphere stroke on brain activity during speech production in fifty-three patients. The results were related to twenty-four healthy participants. The analyses investigated not only local activity, but also functional connectivity both within and between distributed networks. Although activity within individua...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Geranmayeh, F., Wise, R. Tags: Stroke, Radiology, Radiology (diagnostics) Thur 21, Parallel session 5: Therapeutics Source Type: research

Strokes happen round the clock, but why is stroke care worse on weekends and overnight?
Walk into a typical acute hospital on a weekend or overnight, and it feels like a very different place than on a weekday. Most laboratories, theatres and diagnostics run reduced services, the corridors are quiet, and you are more likely to see a doctor or nurse rushing to an emergency than walking the wards on consults or rounds. Strokes however do not happen only when the hospital is best prepared, with 6 in 10 strokes occurring overnight or on weekends. This discontinuity between the provision of healthcare across the working week and the presentation of stroke has raised concerns that patients admitted on weekends and o...
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 14, 2016 Category: Neurosurgery Authors: Rudd, A. G., Bray, B. Tags: Stroke Editorial commentaries Source Type: research

Infarct growth despite full reperfusion in endovascular therapy for acute ischemic stroke
Conclusions Despite full reperfusion, infarct growth is relatively frequent and may explain poor clinical outcomes in this setting. Ethnicity was found to influence SIG. Use of IV t-PA and stent-retrievers were associated with less infarct core expansion.
Source: Journal of NeuroInterventional Surgery - January 13, 2016 Category: Neurosurgery Authors: Haussen, D. C., Nogueira, R. G., Elhammady, M. S., Yavagal, D. R., Aziz-Sultan, M. A., Johnson, J. N., Gaynor, B. G., Jen, S., Dehkharghani, S., Peterson, E. C. Tags: Ischemic stroke Source Type: research

Relative CBV ratio on perfusion-weighted MRI indicates the probability of early recanalization after IV t-PA administration for acute ischemic stroke
Conclusions The results of this study suggest that the rCBV ratio on PWI might serve as a useful indicator of ER after IV t-PA administration.
Source: Journal of NeuroInterventional Surgery - February 14, 2016 Category: Neurosurgery Authors: Sohn, S.-W., Park, H.-S., Cha, J.-K., Kim, D.-H., Kang, M.-J., Choi, J.-H., Nah, H.-W., Huh, J.-T. Tags: Ischemic stroke Source Type: research