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Melatonin as an Antioxidant for Stroke Neuroprotection.
Abstract Melatonin (N-acetyl-5-methoxytryptamine) is a hormone derived from the pineal gland that has wide range of clinical application. While melatonin was originally assessed as a hormone specializing in regulation of the normal circadian rhythm in mammals, it now has been shown to be an effective free radical scavenger and antioxidant. Current research has focused on Central Nervous System (CNS) disorders, stroke in particular, for potential melatonin-based therapeutics. As of now, the realm of potential therapy regimens is focused on three main treatments: exogenously delivered melatonin, pineal gland graftin...
Source: Cell Transplantation - October 22, 2015 Category: Cytology Authors: Watson N, Diamandis T, Gonzales-Portillo C, Reyes S, Borlongan CV Tags: Cell Transplant Source Type: research