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Is There Benefit from Stenting on Cognitive Function in Intracranial Atherosclerosis
Background: Revascularization of stenotic cerebral arteries is hypothesized to improve cognition by increasing cerebral perfusion.Aims: We compared cognition impairment among patients treated with percutaneous angioplasty and stenting (PTAS) and aggressive medical management (AMM) versus AMM alone in the Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis (SAMMPRIS) Trial.Methods: In SAMMPRIS, 451 patients with recent transient ischemic attack or stroke attributed to 70-99% intracranial stenosis were randomized to PTAS plus AMM or AMM alone. Patients who had stroke as the qualifying event with Nat...
Source: Cerebrovascular Diseases - November 8, 2016 Category: Neurology Source Type: research

Treatment Trends In Management Of Intracranial Stenosis In The Pre- And Post-Sammpris Era (I8-1.008)
DISCUSSION: SAMMPRIS had a major impact on treatment trends of physicians managing patients with intracranial stenosis. In the Post-SAMMPRIS survey, 91% of respondents participating in SAMMPRIS and 82% of overall respondents indicated that the SAMMPRIS results changed the way they managed patients with ICAS.As aggressive medical management coupled with optimal risk factor reduction shows promise in reducing rates of recurrent stroke, a novel endovascular therapy will have to seek newer heights of increasing RRR to gain acceptance by practitioners.Disclosure: Dr. Pawar has nothing to disclose. Dr. Turan has received persona...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pawar, S., Turan, T., Cotsonis, G., Lynn, M., Wooley, R., Stern, B., Derdeyn, C., Fiorella, D., Chimowitz, M. Tags: Clinical Decision Making After the Dust Settles on Clinical Trials Poster Presentations Source Type: research

Treatment Trends In Management Of Intracranial Stenosis In The Pre- And Post-Sammpris Era (P1.146)
DISCUSSION: SAMMPRIS had a major impact on treatment trends of physicians managing patients with intracranial stenosis. In the Post-SAMMPRIS survey, 91% of respondents participating in SAMMPRIS and 82% of overall respondents indicated that the SAMMPRIS results changed the way they managed patients with ICAS.As aggressive medical management coupled with optimal risk factor reduction shows promise in reducing rates of recurrent stroke, a novel endovascular therapy will have to seek newer heights of increasing RRR to gain acceptance by practitioners.Disclosure: Dr. Pawar has nothing to disclose. Dr. Turan has received persona...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pawar, S., Turan, T., Cotsonis, G., Lynn, M., Wooley, R., Stern, B., Derdeyn, C., Fiorella, D., Chimowitz, M. Tags: Cerebrovascular Disease and Interventional Neurology: Intracranial Disease Source Type: research