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Community planning for a "healthy built environment" via a human-environment nexus? A multifactorial assessment of environmental characteristics and age-specific stroke mortality in Hong Kong
In conclusion, urban plans and designs for stroke mortality prevention should implement age-specific health care to neighborhoods with particular population segments.PMID:34543905 | DOI:10.1016/j.chemosphere.2021.132043
Source: Chemosphere - September 20, 2021 Category: Chemistry Authors: Hung Chak Ho Huagui Guo Ta-Chien Chan Yuan Shi Chris Webster Kenneth N K Fong Source Type: research

Employment of Molecularly Imprinted Polymers to High-throughput Screen nNOS-PSD-95 Interruptions: Structure and Dynamics Investigations on Monomer-Template Complexation.
Abstract We here employ the molecularly imprinted polymers (MIPs) to screen nNOS-PSD-95 interruptions. 5-(3,5-dichloro-2-hydroxybenzylamino)-2-hydroxybenzoic acid (ZL006, a potential drug candidates for the treatment of stroke, depression and pain) was employed as template. Four kinds of functional monomers (2-VP: 2-vinylpyridine; 4-VP: 4-vinylpyridine; MMA: methyl methacrylate; MAAM: methacrylamide) were designed, and their complexation with ZL006 in various solvents (methanol, acetonitrile, toluene, chloroform) were investigated by molecular dynamics (MD) simulations and quantum mechanics (QM) calculations. Both...
Source: Chemphyschem - January 5, 2016 Category: Chemistry Authors: Jiang N, Wang Y, Zhao T, Dai P, Li F Tags: Chemphyschem Source Type: research