• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Commentary: Mid-term outcomes in a real-world transcatheter aortic valve replacement population
In this edition of the Journal, Percy and colleagues1 present a series of 866 patients who underwent transfemoral transcatheter aortic valve replacement (TAVR) at Brigham and Women's Hospital between 2011 and 2018. The authors compared 5-year survival in patients with and without periprocedural complications. The complications of interest were periprocedural stroke, paravalvular leak (PVL), new left bundle branch block, and permanent pacemaker (PPM) implantation. These complications appear to occur more frequently after TAVR than surgical aortic valve replacement (SAVR) in some randomized trials.
Source: The Journal of Thoracic and Cardiovascular Surgery - May 14, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Rachel Eikelboom, Aaron J. Spooner, Michael H. Yamashita Tags: Commentary Source Type: research

Commentary: In the era of mitral valve-in-valve therapy, mechanical prosthesis in young patients does not deserve to be forgotten
Chen and colleagues1 from Memorial Hospital of Taoyaun in Taiwan analyzed, retrospectively, the results of patients who received either biological or mechanical valve for mitral valve replacement in rheumatic heart disease. Patient data were extracted from the National Health Insurance administrative database in Taiwan. Propensity score analysis yielded 2 paired groups of 788 patients. No significant difference in terms of in-hospital mortality were observed between the 2 matched groups. Regarding late outcomes, all-cause mortality at 10  years was in favor of the mechanical valve group, risk of stroke tended to be higher...
Source: The Journal of Thoracic and Cardiovascular Surgery - April 1, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Francesco Formica, Francesco Maestri, Francesco Nicolini Tags: Commentary Source Type: research

STS-ACC TVT Registry of Transcatheter Aortic Valve Replacement.
Abstract The STS-ACC TVT Registry (Society of Thoracic Surgeons-American College of Cardiology Transcatheter Valve Therapy Registry) from 2011 to 2019 has collected data on 276,316 patients undergoing transcatheter aortic valve replacement (TAVR) at sites in all U.S. states. Volumes have increased every year, exceeding surgical aortic valve replacement in 2019 (72,991 vs. 57,626), and it is now performed in all U.S. states. TAVR now extends from extreme- to low-risk patients. This is the first presentation on 8,395 low-risk patients treated in 2019. In 2019, for the entire cohort, femoral access increased to 95.3%...
Source: The Annals of Thoracic Surgery - February 1, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Carroll JD, Mack MJ, Vemulapalli S, Herrmann HC, Gleason TG, Hanzel G, Deeb GM, Thourani VH, Cohen DJ, Desai N, Kirtane AJ, Fitzgerald S, Michaels J, Krohn C, Masoudi FA, Brindis RG, Bavaria JE Tags: Ann Thorac Surg Source Type: research

Robotic Approach to Mitral Valve Surgery in Septo-Octogenarians
This summarizes the incidence of septo-octogenarian patients in our robotic mitral experience and provides comparative outcomes to STS predicted models of mortality, stroke, and shortened length of stay, demonstrating that elderly patients ( ≥70 years) matched STS benchmarks and outperforming STS predicted short length of stay in this study population. NYHA = New York Heart Association. PCI = percutaneous coronary intervention. LOS = length of stay. STS = Society of Thoracic Surgeons.Advanced age confers higher STS pre dicted risks of mortality (PROM) and longer hospital lengths of stay (LOS) in patients ...
Source: Seminars in Thoracic and Cardiovascular Surgery - January 16, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Neel K. Ranganath, Didier F. Loulmet, Siyamek Neragi-Miandoab, Jad Malas, Lily Spellman, Aubrey C. Galloway, Eugene A. Grossi Tags: ADULT – Original Submission Source Type: research

Predictors and Prognostic Impact of In-hospital Bleeding after Transcatheter Aortic Valve Replacement According to BARC and VARC-2 Definitions
Abstract Pulmonary endarterectomy is a curative procedure for chronic thromboembolic Pulmonary Hypertension. As usual, cardiopulmonary bypass circuit is required. However, there are several complications attributed to extracorporeal circulation. Hemodilution, systemic inflammatory response syndrome and leukocyte sequestration are circulation related complications. The severe forms include Acute Respiratory Distress Syndrome, Acute Lung Injury, myocardial stunning, dysfunction of the right ventricle, coagulopathy, postoperative stroke or renal dysfunction. In this case report, we aimed to give information about perioperativ...
Source: Revista Brasileira de Cirurgia Cardiovascular - December 3, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

Commentary: Atrial fibrillation after aortic valve replacement: Predict, prevent, protect
When atrial fibrillation (AF) occurs after cardiac surgery, surgeons consider the arrhythmia a nuisance rather than a complication. This reflects natural optimism. Although perioperative AF is most often self-limited, it is associated with increased risk of stroke and death, increased hospital length of stay, and increased health care costs.1 Still, we tend not to worry too much because postoperative AF tends to resolve regardless of treatment strategy.1
Source: The Journal of Thoracic and Cardiovascular Surgery - June 13, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Marc Gillinov, Edward G. Soltesz Tags: Commentary Source Type: research

Stented Versus Stentless Aortic Valve Replacement in Patients With Small Aortic Root: A Systematic Review and Meta-Analysis
Objective The aim of the study was to compare hemodynamic and perioperative outcomes of stented against stentless aortic valve replacement in patients with small aortic root (21 mm or less). Methods A comprehensive search was undertaken among the four major databases (PubMed, Embase, Scopus, and Ovid) to identify all randomized and nonrandomized controlled trials comparing stentless to stented bioprosthetic valves in small aortic root patients. Odds ratios, weighted mean differences, or standardized mean differences and their 95% confidence intervals were analyzed. Results A total of seven studies with a total of 9...
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - November 1, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Myocardial Protection and Financial Considerations of Custodiol Cardioplegia in Minimally Invasive and Open Valve Surgery
Objective: Single-dose antegrade crystalloid cardioplegia with Custodiol-HTK (histidine-tryptophan-ketoglutarate) has been used for many years. Its safety and efficacy were established in experimental and clinical studies. It is beneficial in complex valve surgery because it provides a long period of myocardial protection with a single dose. Thus, valve procedures (minimally invasive or open) can be performed with limited interruption. The aim of this study is to compare the use of Custodiol-HTK cardioplegia with traditional blood cardioplegia in patients undergoing minimally invasive and open valve surgery. Methods: A si...
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - November 1, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Original Articles Source Type: research

Transaortic Transcatheter Aortic Valve Implantation and Concomitant Off Pump Revascularization
We present 4 successfully combined off-pump procedures consisting of a transcatheter aortic valve implantation (Edwards SAPIEN XT) via the transaortic approach and an off-pump coronary artery bypass grafting. All patients were discharged free from stroke, myocardial infarction, or access site complications either to rehabilitation facility or to the referring hospital with none or trace aortic regurgitation and patent grafts. These cases confirm the feasibility of those combined operations and should be considered as realistic alternative for surgical treatment in high-risk patients who are clearly identified to benefit fr...
Source: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery - September 1, 2016 Category: Cardiovascular & Thoracic Surgery Tags: Case Reports Source Type: research

In-hospital mortality and stroke after surgical aortic valve replacement: A nationwide perspective
Stroke is a widely recognized complication after aortic valve replacement (AVR), especially among elderly patients. The literature contains substantial variability in reports of the actual incidence of stroke after AVR among high-risk patients. Our objective was to define risk of stroke in patients undergoing surgical AVR, using a large national database.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 4, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Shikhar Agarwal, Aatish Garg, Akhil Parashar, Lars G. Svensson, E. Murat Tuzcu, Jose L. Navia, Stephanie Mick, Samir R. Kapadia Tags: Acquired cardiovascular disease Source Type: research

In-hospital Mortality and Stroke Following Surgical Aortic Valve Replacement: A Nationwide Perspective
Stroke is a widely recognized complication following aortic valve replacement (AVR), especially among elderly patients. Significant heterogeneity exists in the current literature around the actual incidence of stroke following AVR among high-risk patients. Our objective was to define risk of stroke in patients undergoing surgical AVR from a large national database.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 4, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Shikhar Agarwal, Aatish Garg, Akhil Parashar, Lars G. Svensson, E. Murat Tuzcu, Jose Navia, Stephanie Mick, Samir R. Kapadia Source Type: research

Protecting the aorta during transcatheter aortic valve replacement: Have we found the answer?
Neurologic injury ranging from transient cognitive dysfunction to catastrophic permanent stroke constitutes the single main morbidity of cardiac surgery and largely affects modern transcatheter aortic valve replacement (TAVR).1-3 Today, the incidence of cerebrovascular events after TAVR ranges from 3% to 7%.4 In the current report, Samim and colleagues5 have explored one of the novel embolic protection devices (EPDs) aimed at reducing these extremely pervasive complications that often carry surmountable challenges to the patient in terms of a reduction in functional status and quality of life, and the healthcare provider i...
Source: The Journal of Thoracic and Cardiovascular Surgery - December 6, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Hanna A. Jensen, Amjad Syed, Vinod H. Thourani Tags: Editorial commentary Source Type: research

Effect of severe left ventricular systolic dysfunction on hospital outcome after transcatheter aortic valve implantation or surgical aortic valve replacement: Results from a propensity-matched population of the Italian OBSERVANT multicenter study
Objective: Despite demonstration of the superior outcomes of transcatheter aortic valve implantation (TAVI) versus optimal medical therapy for severe left ventricular systolic dysfunction, studies comparing TAVI and surgical aortic valve replacement (AVR) in this high-risk group have been lacking.Methods: We performed propensity matching for age, gender, baseline comorbidities, previous interventions, priority at hospital admission, frailty score, New York Heart Association class, EuroSCORE, and associated cardiac diseases. Next, the 30-day mortality and procedure-related morbidity of 162 patients (81 TAVI vs 81 AVR) with ...
Source: The Journal of Thoracic and Cardiovascular Surgery - November 21, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Francesco Onorati, Paola D’Errigo, Claudio Grossi, Marco Barbanti, Marco Ranucci, Daniel Remo Covello, Stefano Rosato, Alice Maraschini, Gennaro Santoro, Corrado Tamburino, Fulvia Seccareccia, Francesco Santini, Lorenzo Menicanti, OBSERVANT Research Gro Tags: Acquired Cardiovascular Disease Source Type: research