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Statins Have a Dose-Dependent Effect on Amputation and Survival in Peripheral Artery Disease Patients.
Conclusions -Statins, especially high intensity formulations, are underutilized in PAD patients. This is the first population based study to show that high intensity statin use at time of PAD diagnosis is associated with a significant reduction in limb loss and mortality compared to low-moderate intensity statin users as well as patients treated only with antiplatelet medications but not with statins.
PMID: 29330214 [PubMed - as supplied by publisher]
Source: Circulation - January 12, 2018 Category: Cardiology Authors: Arya S, Khakharia A, Binney ZO, DeMartino RR, Brewster LP, Goodney PP, Wilson PWF Tags: Circulation Source Type: research
