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When the World Throws You a Curve Ball: Lessons Learned in Breast Cancer Management
Am Soc Clin Oncol Educ Book. 2021 Mar;41:1-11. doi: 10.1200/EDBK_320691.ABSTRACTIn the care of patients with operable breast cancer, there has been a shift toward increasing use of neoadjuvant therapy. There are benefits to neoadjuvant therapy, such as monitoring for response, as well as an increased rate of breast conservation and reduction of potential morbidity associated with breast surgery, including axillary management. Among patients with highly proliferative tumors, such as HER2-positive or triple-negative breast cancer, those with residual disease are at higher risk of recurrence, which informs the recommended sys...
Source: Clinical Genitourinary Cancer - May 6, 2021 Category: Cancer & Oncology Authors: Samilia Obeng-Gyasi Charlotte E Coles Jade Jones Ruth Sacks Sara Lightowlers Judith M Bliss A Murray Brunt Joanne S Haviland Anna M Kirby Kevin Kalinsky Source Type: research

Neoadjuvant PD-1 inhibitors and chemotherapy for locally advanced NSCLC: A retrospective study
CONCLUSIONS: Induction ICI-chemotherapy may be a valid treatment in patients with locally advanced NSCLC, providing important tumor downstaging and rendering patients operable. In our experience patients had few side effects and a good pathological response.PMID:33781737 | DOI:10.1016/j.athoracsur.2021.03.041
Source: The Annals of Thoracic Surgery - March 30, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Tianxiang Chen Junwei Ning Alessio Campisi Andrea Dell'Amore Angelo Paolo Ciarrocchi Ziming Li Liwei Song Jia Huang Yunhai Yang Franco Stella Qingquan Luo Source Type: research