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GSE173713 RNA Sequencing of WT Aged Vehicle vs. HPBCD Infarcts
Contributors : Danielle A Becktel ; Kristian P DoyleSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe systematically characterized the transcriptomes of stroke infarcts in vehicle- and HP βCD-treated aged (18-month-old) mice by performing bulk RNA-Seq on infarcted brain tissue collected 7 weeks after distal middle cerebral artery occlusion + hypoxia (DH) stroke. The DE analysis revealed 991 upregulated genes and 1,876 downregulated genes. HPβCD treatment upregulated intracellular c holesterol transporters, lipoproteins, and lipoprotein receptors, such as Npc1, Npc2, Apoe, Trem2, Ab...
Source: GEO: Gene Expression Omnibus - May 3, 2021 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research