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Infectious Disease: Tuberculosis
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Total 35529 results found since Jan 2013.
Infectiousness of HIV Seropositive Tuberculosis Patients in a High-burden African Setting.
CONCLUSIONS: This study suggests that HIV seropositive tuberculosis cases may be less infectious than seronegative patients only when they are smear-negative or lack cavitary lung disease. These results may explain heterogeneity between prior studies and provide evidence suggesting that tuberculosis contact investigation should include HIV seropositive index cases in high disease burden settings.
PMID: 27181053 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 14, 2016 Category: Respiratory Medicine Authors: Martinez L, Sekandi JN, Castellanos ME, Zalwango S, Whalen CC Tags: Am J Respir Crit Care Med Source Type: research
Activation Profile of Mycobacterium tuberculosis-Specific CD4(+) T Cells Reflects Disease Activity Irrespective of HIV Status.
PMID: 27248590 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - May 31, 2016 Category: Respiratory Medicine Authors: Wilkinson KA, Oni T, Gideon HP, Goliath R, Wilkinson RJ, Riou C Tags: Am J Respir Crit Care Med Source Type: research
Diagnosis of Latent Tuberculosis Infection in HIV-infected Pregnant Women. "Baby Steps" toward Better Tuberculosis Control in Pregnancy.
PMID: 27304241 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - June 14, 2016 Category: Respiratory Medicine Authors: Zenner D, Ashkin D Tags: Am J Respir Crit Care Med Source Type: research
Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Tuberculosis Patients.
CONCLUSIONS: These observations demonstrate a novel Rpf-independent DCTB population in sputum and reveal that reduced host immunity is associated with lower prevalence of CF-responsive bacteria. Quantification of DCTB in standard TB diagnosis would be beneficial as these organisms provide a putative biomarker to monitor treatment response and risk of disease recurrence.
PMID: 27387272 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - July 6, 2016 Category: Respiratory Medicine Authors: Chengalroyen MD, Beukes GM, Gordhan BG, Streicher EM, Churchyard G, Hafner R, Warren R, Otwombe K, Martinson N, Kana BD Tags: Am J Respir Crit Care Med Source Type: research
Update in Tuberculosis/Pulmonary Infections 2015.
PMID: 27420359 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - July 14, 2016 Category: Respiratory Medicine Authors: Koenig SP, Furin J Tags: Am J Respir Crit Care Med Source Type: research
Tuberculosis-induced Fish-scale Degeneration of the Central Airways.
PMID: 27494060 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - August 4, 2016 Category: Respiratory Medicine Authors: Fois A, Trisolini R, Canu S, Pirina P Tags: Am J Respir Crit Care Med Source Type: research
The Replacement Principle of Tuberculosis. Why Prevention Matters.
PMID: 27525460 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - August 14, 2016 Category: Respiratory Medicine Authors: Whalen CC Tags: Am J Respir Crit Care Med Source Type: research
New Guidelines for the Treatment of Drug-susceptible Tuberculosis from the American Thoracic Society, Centers for Disease Control and the Infectious Disease Society of America: Now Comes the Hard Part.
PMID: 27556737 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - August 23, 2016 Category: Respiratory Medicine Authors: Metersky ML, Schluger NW Tags: Am J Respir Crit Care Med Source Type: research
Interstitial Lung Disease (ILD) in India: Results of a Prospective Registry.
CONCLUSIONS: The majority of patients with ILD in India have HP followed by CTD-ILD and IPF; diagnoses varied between site investigators and CILD experts in the US, emphasizing the value of MDD in ILD diagnosis. Prompted case report forms including environmental exposures in prospective registries will likely provide further insight into the etiology, understanding and management of ILD worldwide.
PMID: 27684041 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 28, 2016 Category: Respiratory Medicine Authors: Singh S, Collins BF, Sharma BB, Joshi JM, Talwar D, Katiyar S, Singh N, Ho L, Samaria JK, Bhattacharya P, Gupta R, Chaudhari S, Singh T, Moond V, Pipavath S, Ahuja J, Chetambath R, Ghoshal AG, Jain NK, Devi HG, Kant S, Koul P, Dhar R, Swarnakar R, Sharma Tags: Am J Respir Crit Care Med Source Type: research
Preventing Acquired Resistance to Bedaquiline and Delamanid in Multidrug-Resistant Tuberculosis Treatment Requires Optimal Management.
PMID: 27797614 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - October 31, 2016 Category: Respiratory Medicine Authors: Guglielmetti L, Le Dû D, Fréchet-Jachym M, Mitnick C Tags: Am J Respir Crit Care Med Source Type: research
Contact Investigation: A Priority for Tuberculosis Control Programs.
PMID: 27797611 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - October 31, 2016 Category: Respiratory Medicine Authors: Saunders MJ, Datta S Tags: Am J Respir Crit Care Med Source Type: research
Infectiousness of HIV-Seropositive Patients with Tuberculosis in a High-Burden African Setting.
CONCLUSIONS: This study suggests that HIV-seropositive tuberculosis cases may be less infectious than HIV-seronegative patients only when they are smear-negative or lack cavitary lung disease. These results may explain heterogeneity between prior studies and provide evidence suggesting that tuberculosis contact investigation should include HIV-seropositive index cases in high disease burden settings.
PMID: 27181053 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - October 31, 2016 Category: Respiratory Medicine Authors: Martinez L, Sekandi JN, Castellanos ME, Zalwango S, Whalen CC Tags: Am J Respir Crit Care Med Source Type: research
SP110b Controls Host Immunity and Susceptibility to Tuberculosis.
CONCLUSIONS: These results indicate that SP110b plays a crucial role in shaping the inflammatory milieu supporting host protection during infection by fine-tuning NF-κB activity, suggesting that SP110b may serve as a potential target for host-directed therapy aiming to manipulate the host immunity against TB.
PMID: 27858493 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - November 17, 2016 Category: Respiratory Medicine Authors: Leu JS, Chen ML, Chang SY, Yu SL, Lin CW, Wang H, Chen WC, Chang CH, Wang JY, Lee LN, Yu CJ, Kramnik I, Yan BS, Yang PC Tags: Am J Respir Crit Care Med Source Type: research
New Evidence for the Complexity of the Population Structure of Mycobacterium tuberculosis Increases the Diagnostic and Biologic Challenges.
PMID: 27976945 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - December 14, 2016 Category: Respiratory Medicine Authors: Dartois V, Saito K, Warrier T, Nathan C Tags: Am J Respir Crit Care Med Source Type: research
Safety and Immunogenicity of Adenovirus 35 TB Vaccine Candidate in Adults with Active or Previous TB: a Randomized Trial.
CONCLUSIONS: Administration of the AERAS-402 candidate tuberculosis vaccine to participants with current or previous pulmonary tuberculosis induced a robust immune response and is not associated with clinically significant pulmonary complications. Clinical trial registration available at www.clinicaltrials.gov, ID NCT02414828.
PMID: 28060545 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 5, 2017 Category: Respiratory Medicine Authors: van Zyl-Smit RN, Esmail A, Bateman ME, Dawson R, Goldin J, van Rikxoort E, Douoguih M, Pau MG, Sadoff JC, McClain JB, Snowden MA, Benko J, Hokey DA, Rutkowski KT, Graves A, Shepherd B, Ishmukhamedov S, Kagina BM, Abel B, Hanekom WA, Scriba TJ, Bateman ED Tags: Am J Respir Crit Care Med Source Type: research
