Filtered By:
Infectious Disease: Tuberculosis

This page shows you your search results in order of relevance. This is page number 3.

Order by Relevance | Date

Total 35529 results found since Jan 2013.

Acceleration of Tuberculosis Treatment by Adjunctive Therapy with Verapamil as an Efflux Inhibitor.
Conclusions: These data demonstrate treatment shortening by verapamil adjunctive therapy in mice and strongly support further study of verapamil and other efflux pump inhibitors in human tuberculosis. PMID: 23805786 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - June 27, 2013 Category: Respiratory Medicine Authors: Gupta S, Tyagi S, Almeida D, Maiga M, Ammerman N, Bishai W Tags: Am J Respir Crit Care Med Source Type: research

Assessment of Clofazimine Activity in a Second-Line Regimen for Tuberculosis in Mice.
Conclusion. The clofazimine contribution was substantial in these experimental conditions. PMID: 23822735 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - July 3, 2013 Category: Respiratory Medicine Authors: Grosset JH, Tyagi S, Almeida DV, Converse PJ, Li SY, Ammerman NC, Bishai WR, Enarson D, Trébucq A Tags: Am J Respir Crit Care Med Source Type: research

Rationalizing Use of Fluoroquinolones and Pyrazinamide in the Battle against Multidrug-Resistant Tuberculosis.
PMID: 23815718 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - July 1, 2013 Category: Respiratory Medicine Authors: Chang KC, Dheda K Tags: Am J Respir Crit Care Med Source Type: research

Enhanced Innate Immunity as Explanation for Reduced Mycobacterium tuberculosis Infection in Bacillus Calmette-Guérin-immunized Children.
PMID: 23855702 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - July 15, 2013 Category: Respiratory Medicine Authors: Eisenhut M Tags: Am J Respir Crit Care Med Source Type: research

Increased Frequency of Myeloid Derived Suppressor Cells during Active Tuberculosis and Following Recent Mycobacterium tuberculosis Infection Suppresses T Cell Function.
Conclusion: These data reveal that innate MDSCs are induced not only during active TB at similar levels as found in cancer, but also in healthy individuals after recent exposure to M.tb. These cells diminish protective T cell responses and may contribute to the inability of hosts to eradicate the infection and add to the subsequent development of TB disease. PMID: 23885784 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - July 25, 2013 Category: Respiratory Medicine Authors: du Plessis N, Loebenberg L, Kriel M, von Groote-Bidlingmaier F, Ribechini E, Loxton AG, van Helden PD, Lutz MB, Walzl G Tags: Am J Respir Crit Care Med Source Type: research

Challenges with QuantiFERON-TB Gold Assay for Large-Scale, Routine Screening of US Healthcare Workers.
Conclusions. The manufacturer's definition of QFT conversion results in an inflated conversion rate that is incompatible with our low risk setting. A significantly higher QFT cutoff value is needed to match the historical TST conversion rate. Non-reproducible conversions in a majority of converters suggested false positive results. PMID: 23978270 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - August 26, 2013 Category: Respiratory Medicine Authors: Slater ML, Welland G, Pai M, Parsonnet J, Banaei N Tags: Am J Respir Crit Care Med Source Type: research

S100A8/A9 Proteins Mediate Neutrophilic Inflammation and Lung Pathology during Tuberculosis.
Conclusions: Our results thus show a major pathological role for S100A8/A9 proteins in mediating neutrophil accumulation and inflammation associated with TB, thus targeting specific molecules such as S100A8/A9 proteins, has the potential to decrease lung tissue damage without impacting protective immunity against TB. PMID: 24047412 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 18, 2013 Category: Respiratory Medicine Authors: Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna K, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Cumming B, Kasprowi Tags: Am J Respir Crit Care Med Source Type: research

Fluoroquinolones in the Treatment of Tuberculosis: Which Is Best?
PMID: 24083858 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - October 1, 2013 Category: Respiratory Medicine Authors: Schluger NW Tags: Am J Respir Crit Care Med Source Type: research

Update in tuberculosis and nontuberculous mycobacterial disease 2012.
Abstract In 2012, new publications in the Journal described both the predictive value of the new IFN-γ release assays for diagnosis of latent tuberculosis (TB), but also provided evidence that these new tests cannot be interpreted simply as positive or negative, as initially hoped. Surgical masks can reduce transmission of TB infection, but other measures such as state-wide implementation of targeted testing and treatment of latent TB or active case finding require substantial and sustained effort to successfully reduce TB morbidity and mortality. A quasiexperimental study revealed that a package of social interv...
Source: American Journal of Respiratory and Critical Care Medicine - October 15, 2013 Category: Respiratory Medicine Authors: Menzies D, Nahid P Tags: Am J Respir Crit Care Med Source Type: research

Interbronchial fistula by endobronchial tuberculosis.
PMID: 24236601 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - November 15, 2013 Category: Respiratory Medicine Authors: Lee SJ, Jin KN, Park SS, Kim DK, Chung HS, Heo EY Tags: Am J Respir Crit Care Med Source Type: research

Interferon-γ Release Assays and Tuberculin Skin Testing for Diagnosis of Latent Tuberculosis Infection in Healthcare Workers in the United States.
Conclusions: Most conversions among HCWs in low TB incidence settings appear to be false-positives and these occurred 6-9 times more frequently with IGRAs than TST; repeat testing of apparent converters is warranted. PMID: 24299555 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - December 3, 2013 Category: Respiratory Medicine Authors: Dorman SE, Belknap R, Graviss EA, Reves R, Schluger N, Weinfurter P, Wang Y, Cronin W, Hirsch-Moverman Y, Teeter LD, Parker M, Garrett DO, Daley CL, for the Tuberculosis Epidemiologic Studies Consortium Tags: Am J Respir Crit Care Med Source Type: research

Persistent Latent Tuberculosis Reactivation Risk in US Immigrants.
Conclusions High post-arrival TB rates were due to detection of imported TB through active post-arrival surveillance. Among immigrants without active TB at baseline, reported TB did not decline over nine years, indicating sustained high risk of LTBI reactivation. Revised guidelines should support LTBI screening and treatment >5 years following U.S. arrival. PMID: 24308495 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - December 5, 2013 Category: Respiratory Medicine Authors: Walter ND, Painter J, Parker M, Lowenthal P, Flood J, Fu Y, Asis R, Reves R, for the TB Epidemiologic Studies Consortium Tags: Am J Respir Crit Care Med Source Type: research

Risk for Tuberculosis in Child Contacts: Development and Validation of a Predictive Score.
Conclusions: A risk predictive score was developed and validated to identify child contacts aged 0-12 years at increased risk for active TB. This predictive score can help to prioritize active case-finding or isoniazid preventive therapy among children exposed to TB. PMID: 24304428 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - December 4, 2013 Category: Respiratory Medicine Authors: Chan PC, Peng SS, Chiou MY, Ling DL, Chang LY, Wang KF, Fang CT, Huang LM Tags: Am J Respir Crit Care Med Source Type: research

Tuberculosis and High Altitude: Worth a Try in XDR-TB?
Abstract Not Needed. PMID: 24383447 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 2, 2014 Category: Respiratory Medicine Authors: Murray JF Tags: Am J Respir Crit Care Med Source Type: research

Serial screening for latent tuberculosis infection in healthcare workers in low-risk settings.
PMID: 24381985 [PubMed - in process]
Source: American Journal of Respiratory and Critical Care Medicine - January 1, 2014 Category: Respiratory Medicine Authors: Zellweger JP, Rieder HL Tags: Am J Respir Crit Care Med Source Type: research