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Infectious Disease: Tuberculosis
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Total 35529 results found since Jan 2013.
Early Bactericidal Activity of Meropenem Plus Clavulanate (+/-Rifampin) For TB: The COMRADE Randomized, Phase 2 Trial
CONCLUSIONS: Bactericidal activity was greater with the World Health Organization recommended total daily dose of 6 grams daily than a lower dose of 3 grams daily. This difference was only detectable with solid culture. Tolerability of intravenous meropenem, with amoxicillin/clavulanate, though, was poor at all doses, calling into question the utility of this drug in second-line regimens. Clinical trial registration available at www.CLINICALTRIALS: gov, ID: NCT03174184.PMID:35258443 | DOI:10.1164/rccm.202108-1976OC
Source: American Journal of Respiratory and Critical Care Medicine - March 8, 2022 Category: Respiratory Medicine Authors: Veronique De Jager Nikhil Gupte Silvia Nunes Grace L Barnes Rob Christiaan van Wijk Joni Mostert Susan E Dorman Ahmed A Abulfathi Caryn M Upton Alan Faraj Eric L Nuermberger Gyanu Lamichhane Elin M Svensson Ulrika Simonsson Andreas H Diacon Kelly E Dooley Source Type: research
Treatments of Multidrug-Resistant Tuberculosis: Light at the End of the Tunnel
Am J Respir Crit Care Med. 2022 Mar 23. doi: 10.1164/rccm.202202-0393ED. Online ahead of print.NO ABSTRACTPMID:35320062 | DOI:10.1164/rccm.202202-0393ED
Source: American Journal of Respiratory and Critical Care Medicine - March 23, 2022 Category: Respiratory Medicine Authors: Christoph Lange Clifton E Barry Iii C Robert Horsburgh Source Type: research
< em > Mycobacterium tuberculosis < /em > : A Pathogen That Can Hold its Breath a Long Time
Am J Respir Crit Care Med. 2022 Apr 20. doi: 10.1164/rccm.202203-0432ED. Online ahead of print.NO ABSTRACTPMID:35442854 | DOI:10.1164/rccm.202203-0432ED
Source: American Journal of Respiratory and Critical Care Medicine - April 20, 2022 Category: Respiratory Medicine Authors: Moagi T Shaku William R Bishai Source Type: research
Aerosolization of < em > Mycobacterium tuberculosis < /em > by Tidal Breathing
CONCLUSIONS: Assuming the number of viable Mtb organisms released offers a reliable proxy of patient infectiousness, our observations imply that TiBr and inter-individual variability in Mtb release might be significant contributors to TB transmission among active cases. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).PMID:35584342 | DOI:10.1164/rccm.202110-2378OC
Source: American Journal of Respiratory and Critical Care Medicine - May 18, 2022 Category: Respiratory Medicine Authors: Ryan Dinkele Sophia Gessner Andrea McKerry Bryan Leonard Juane Leukes Ronnett Seldon Digby F Warner Robin Wood Source Type: research
The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis
CONCLUSIONS: Our results strongly support the use of chest radiography as a routine screening tool for the evaluation of child TB contacts, where this is readily available. Radiographic abnormalities not usually considered suggestive of TB may indicate incipient or subclinical disease, although TB preventive treatment is adequate in most cases.PMID:35608549 | DOI:10.1164/rccm.202202-0259OC
Source: American Journal of Respiratory and Critical Care Medicine - May 24, 2022 Category: Respiratory Medicine Authors: Chuan-Chin Huang Qi Tan Mercedes C Becerra Roger Calderon Silvia S Chiang Carmen Contreras Leonid Lecca Judith Jimenez Carlos M Perez-Velez Claudia L Roya-Pabon Rosa Yataco Hai Xu Zibiao Zhang Megan Murray Source Type: research
Aerosolization of < em > Mycobacterium tuberculosis < /em > by Tidal Breathing
CONCLUSIONS: Assuming the number of viable Mtb organisms released offers a reliable proxy of patient infectiousness, our observations imply that TiBr and inter-individual variability in Mtb release might be significant contributors to TB transmission among active cases. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).PMID:35584342 | DOI:10.1164/rccm.202110-2378OC
Source: American Journal of Respiratory and Critical Care Medicine - May 18, 2022 Category: Respiratory Medicine Authors: Ryan Dinkele Sophia Gessner Andrea McKerry Bryan Leonard Juane Leukes Ronnett Seldon Digby F Warner Robin Wood Source Type: research
Coughing is Not Required to Transmit < em > Mycobacterium tuberculosis < /em > : Another Nail in the Coffin
Am J Respir Crit Care Med. 2022 May 25. doi: 10.1164/rccm.202204-0645ED. Online ahead of print.NO ABSTRACTPMID:35612825 | DOI:10.1164/rccm.202204-0645ED
Source: American Journal of Respiratory and Critical Care Medicine - May 25, 2022 Category: Respiratory Medicine Authors: David W Dowdy Source Type: research
The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis
CONCLUSIONS: Our results strongly support the use of chest radiography as a routine screening tool for the evaluation of child TB contacts, where this is readily available. Radiographic abnormalities not usually considered suggestive of TB may indicate incipient or subclinical disease, although TB preventive treatment is adequate in most cases.PMID:35608549 | DOI:10.1164/rccm.202202-0259OC
Source: American Journal of Respiratory and Critical Care Medicine - May 24, 2022 Category: Respiratory Medicine Authors: Chuan-Chin Huang Qi Tan Mercedes C Becerra Roger Calderon Silvia S Chiang Carmen Contreras Leonid Lecca Judith Jimenez Carlos M Perez-Velez Claudia L Roya-Pabon Rosa Yataco Hai Xu Zibiao Zhang Megan Murray Source Type: research
Coughing is Not Required to Transmit < em > Mycobacterium tuberculosis < /em > : Another Nail in the Coffin
Am J Respir Crit Care Med. 2022 May 25. doi: 10.1164/rccm.202204-0645ED. Online ahead of print.NO ABSTRACTPMID:35612825 | DOI:10.1164/rccm.202204-0645ED
Source: American Journal of Respiratory and Critical Care Medicine - May 25, 2022 Category: Respiratory Medicine Authors: David W Dowdy Source Type: research
The Value of Chest Radiography in Tuberculosis Preventive Treatment (TPT) Screening in Children and Adolescents
Am J Respir Crit Care Med. 2022 Jun 2. doi: 10.1164/rccm.202205-1023ED. Online ahead of print.NO ABSTRACTPMID:35653694 | DOI:10.1164/rccm.202205-1023ED
Source: American Journal of Respiratory and Critical Care Medicine - June 2, 2022 Category: Respiratory Medicine Authors: Ben J Marais Stephen M Graham Source Type: research
