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Infectious Disease: COVID-19

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Acute Stroke as the Presenting Symptom of SARS-CoV-2 Infection in a Young Patient with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
Coronavirus disease of 2019 (COVID-19) has currently reached pandemic levels and neurological manifestations, including stroke as the initial presentation, have been increasingly recognized (1-3). Majority of the reported ischemic strokes are large vessel occlusion or embolic appearing strokes and are frequently described in critically ill patients with severe COVID-19 disease (2), but small ischemic strokes have also been reported (4). Recently, stroke as the presenting symptom in younger patients (
Source: Journal of Stroke and Cerebrovascular Diseases - July 18, 2020 Category: Neurology Authors: Gabriela Trifan, Maureen Hillmann, Fernando D. Testai Source Type: research

Care for Patients with Stroke During the COVID-19 Pandemic: Physical Therapy and Rehabilitation Suggestions for Preventing Secondary Stroke
Infection with the novel severe acute respiratory syndrome coronavirus 2 causes the development of the novel 2019 coronavirus disease (COVID-19) and associated clinical symptoms, which typically presents as an upper respiratory syndrome such as pneumonia. Growing evidence indicates an increased prevalence of neurological involvement (e.g., in the form of stroke) during virus infection. COVID-19 has been suggested to be more than a lung infection because it affects the vasculature of the lungs and other organs and increases the risk of thrombosis.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2020 Category: Neurology Authors: Chien-Chih Wang, Jian-Kang Chao, Mong-Lien Wang, Yi-Ping Yang, Chien-Shiu Chien, Wei-Yi Lai, Yi-Chiang Yang, Yu-Hui Chang, Chen-Liang Chou, Chung-Lan Kao Source Type: research

Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19
We present a multicenter case series from 9 centers in the United States of patients with acute neurological deficits consistent with AIS and COVID-19 who were treated with IV tPA.Results: We identified 13 patients (mean age 62 ( ±9.8) years, 9 (69.2%) male).
Source: Journal of Stroke and Cerebrovascular Diseases - July 26, 2020 Category: Neurology Authors: Thiago Carneiro, Jonathan Dashkoff, Lester Y. Leung, Christa O'Hana S. Nobleza, Erika Marulanda-Londono, Mausaminben Hathidara, Sebastian Koch, Nicole Sur, Alexandra Boske, Barbara Voetsch, Hassan Aboul Nour, Daniel J Miller, Ali Daneshmand, Julie Shulman Source Type: research

Environmental factors and hyperacute stroke care activity during the COVID-19 pandemic: An interrupted time-series analysis.
Concerns have arisen regarding patient access and delivery of acute stroke care during the COVID-19 pandemic. We investigated key population level events on activity of the three hyperacute stroke units (HASUs) within Greater Manchester and East Cheshire (GM& EC), whilst adjusting for environmental factors.
Source: Journal of Stroke and Cerebrovascular Diseases - August 3, 2020 Category: Neurology Authors: Matthew Gittins, Christopher Ashton, Neil Holden, Stephen Cross, Srinath Meadipudi, Khalil Kawafi, Ilse Burger, Sarah Rickard, Andy Vail, Jane Molloy, Craig J. Smith Source Type: research

COVID-19 and Stroke: incidence and etiological description in a high-volume center.
An increased rate of thrombotic events has been associated to Coronavirus Disease 19 (COVID-19) with a variable rate of acute stroke. Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2020 Category: Neurology Authors: Manuel Requena, Marta Oliv é, Marian Muchada, Álvaro García-Tornel, Matías Deck, Jesús Juega, Sandra Boned, Noelia Rodríguez-Villatoro, Carlos Piñana, Jorge Pagola, David Rodríguez-Luna, David Hernández, Marta Rubiera, Alejandro Tomasello, Carlos Source Type: research

The effect of COVID-19 on stroke hospitalizations in New York City
Little is known about the effect of the Coronavirus disease 2019 pandemic on stroke care and the impact of the epidemic on acute stroke hospitalizations has not been described.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Charles Esenwa, Michael K. Parides, Daniel L. Labovitz Source Type: research

The prevalence and predictors of post-stroke depression and anxiety during COVID-19 pandemic
In this study, we evaluated the impact of COVID-19 pandemic on the rates of PSD and PSA.
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2020 Category: Neurology Authors: Zakaria M. Ahmed, Mohamed F. Khalil, Ahmed M. Kohail, Islam F. Eldesouky, Ahmed Elkady, Ashfaq Shuaib Source Type: research

Stroke care trends during COVID-19 pandemic in Zanjan Province, Iran. From the CASCADE Initiative: statistical analysis plan and preliminary results
This study examines the changes in stroke epidemiology and care during the COVID-19 pandemic in Zanjan Province, Iran.
Source: Journal of Stroke and Cerebrovascular Diseases - September 15, 2020 Category: Neurology Authors: Abdoreza Ghoreishi, Shahram Arsang-Jang, Ziad Sabaa-Ayoun, Nawaf Yassi, P.N. Sylaja, Yama Akbari, Afshin A. Divani, Jose Biller, Thanh Phan, Sandy Steinwender, Brian Silver, Ramin Zand, Hamidon Bin Basri, Omer M. Iqbal, Annemarei Ranta, Sean Ruland, Eliza Source Type: research

COVID-19 and Stroke: Incidence and Etiological Description in a High-Volume Center
An increased rate of thrombotic events has been associated to Coronavirus Disease 19 (COVID-19) with a variable rate of acute stroke. Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist.
Source: Journal of Stroke and Cerebrovascular Diseases - August 5, 2020 Category: Neurology Authors: Manuel Requena, Marta Oliv é-Gadea, Marian Muchada, Álvaro García-Tornel, Matías Deck, Jesús Juega, Sandra Boned, Noelia Rodríguez-Villatoro, Carlos Piñana, Jorge Pagola, David Rodríguez-Luna, David Hernández, Marta Rubiera, Alejandro Tomasello, Source Type: research

Stroke as a Neurological Complication of COVID-19: A Systematic Review and Meta-analysis of Incidence, Outcomes and Predictors
COVID-19 is a multi-system infection which predominantly affects the respiratory system, but also causes systemic inflammation, endothelialitis and thrombosis. The consequences of this include renal dysfunction, hepatitis and stroke. In this systematic review, we aimed to evaluate the epidemiology, clinical course, and outcomes of patients who suffer from stroke as a complication of COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - December 15, 2020 Category: Neurology Authors: Isabel Siow, Keng Siang Lee, John J.Y. Zhang, Seyed Ehsan Saffari, Adeline Ng, Barnaby Young Source Type: research

Bilateral large vessel occlusion causing massive ischemic stroke in a covid-19 patient
The case of a 70-year-old male presenting an ischemic stroke related to COVID-19 infection is described. He was initially admitted to the hospital with respiratory insufficiency syndrome secondary to pneumonia caused by SARS Co2. In the next days, he developed rapid neurological deterioration characterized by drowsiness which progressed to deep coma. D-dimer was elevated. Brain CT scan showed bilateral massive ischemic stroke located in the anterior circulation, CT angiogram showed occlusion in the left internal carotid artery and the right middle cerebral artery.
Source: Journal of Stroke and Cerebrovascular Diseases - January 7, 2021 Category: Neurology Authors: Luis A. Robles Tags: Case Report Source Type: research

International survey of Mechanical Thrombectomy Stroke systems of care during COVID-19 pandemic
The COVID-19 pandemic has strained the healthcare systems across the world but its impact on acute stroke care is just being elucidated. We hypothesized a major global impact of COVID-19 not only on stroke volumes but also on various aspects of thrombectomy systems.
Source: Journal of Stroke and Cerebrovascular Diseases - April 6, 2021 Category: Neurology Authors: Dileep R Yavagal, Vasu Saini, Violiza Inoa, Hannah E Gardener, Sheila O Martins, Manav Fakey, Santiago Ortega, Ossama Mansour, Thomas Leung, Ashutosh P Jadhav, Jennifer Potter-Vig, Anurag Mairal, Miao Zhongrong, P.N. Sylaja, Andrew M Demchuk, MT2020 Globa Source Type: research

Outcomes of COVID-19 complications and their possibilities as potential triggers of stroke
The coronavirus disease 2019 (COVID-19) has been a pandemic like no other seen in our times. It has impacted the entire globe affecting more than 180 countries with 81.9 million cases and 1.7 million deaths as of December 29, 20201. Unlike other virus-related spread, COVID-19 since its early days is known to have a high infection rate as well as high mortality, which in turn has resulted in such a devastating impact across the world. The mortality rates among hospitalized patients with COVID-19 infection without stroke range from 22% to 45%2,3, but the mortality was very high (38%) in stroke patients with COVID-19 infections4.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2021 Category: Neurology Authors: Urvish Patel, Preeti Malik, Deep Mehta, Priyanka Rajput, Mashu Shrivastava, Madiha Naveed, Eseosa Urhoghide, Mehwish Martin, Shamima Somi, Richa Jaiswal, Achint Patel, Avantika Israni, Jagmeet Singh, Asim Kichloo, Shamik Shah, Abhishek Lunagariya Source Type: research

Decline in rehab transfers among rehab-eligible stroke patients during the COVID-19 pandemic
: To characterize differences in disposition arrangement among rehab-eligible stroke patients at a Comprehensive Stroke Center before and during the COVID-19 pandemic.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2021 Category: Neurology Authors: Lauren Thau, Taylor Siegal, Mark E. Heslin, Ameena Rana, Siyuan Yu, Scott Kamen, Austin Chen, Nicholas Vigilante, Sheri Gallagher, Kevin Wegner, Jesse M. Thon, Ryna Then, Pratit Patel, Terri Yeager, Tudor G. Jovin, Rohini J. Kumar, David E. Owens, James E Source Type: research

Exploring the relationship between Air Quality and Ischemic Stroke Admissions during the COVID-19 pandemic
Amongst all the global catastrophe due to Coronavirus disease 2019, a significant bright spot is a reduction in air pollution as countries undergo lockdowns to limit the spread of infection. Another reduction that has been reported is in the number of strokes presenting to hospitals, despite the virus implicated in causing a hypercoagulable state. Acute exposure to air pollution has been linked to increase in stroke incidence and the improvement in air quality may be responsible for the decrease in stroke presentations.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2021 Category: Neurology Authors: Sajid Hameed, Maria Khan, Zafar Fatmi, Mohammad Wasay Source Type: research