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Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
CONCLUSION: The rate of adverse reactions after established vaccinations was roughly comparable to previous studies. Two weeks after vaccination, participants in the SARS-CoV-2 vaccination group reported more local and systemic local reactions than participants in the comparator group. In the further course, however, there were no higher odds of medical consultations in either of the two groups. Thus, altogether, we assume comparable safety.TRIAL REGISTRATION: DRKS-ID DRKS00025881 and DRKS-ID DRKS00025373.PMID:37726711 | DOI:10.1186/s12916-023-03064-6
Source: Herpes - September 19, 2023 Category: Infectious Diseases Authors: Felix Werner Nikoletta Zeschick Thomas K ühlein Philipp Steininger Klaus Überla Isabelle Kaiser Maria Sebasti ão Susann Hueber Lisette Warkentin Source Type: research

Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Herpes - August 5, 2023 Category: Infectious Diseases Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research

Lower risk for COVID-19 hospitalization among patients in the United States with past vaccinations for herpes zoster and tetanus, diphtheria and pertussis
Prev Med Rep. 2023 Jun 25;35:102302. doi: 10.1016/j.pmedr.2023.102302. eCollection 2023 Oct.ABSTRACTInfluenza, tetanus, diphtheria, and herpes zoster (HZ) vaccination received within 10 years of the COVID-19 pandemic have been associated with less severe COVID-19 infection. We expanded on this evidence to determine if a receiving two different vaccinations (i.e., HZ and tetanus, diphtheria, and pertussis (Tdap)) was associated with a lower risk for COVID-19 hospitalization. De-identified medical record data from a large mid-western health care system was used to determine if, compared to those with neither HZ or Tdap vacci...
Source: Herpes - July 13, 2023 Category: Infectious Diseases Authors: Joanne Salas John E Morley Daniel F Hoft Jeffrey F Scherrer Source Type: research

Impacts of routine varicella vaccination program and COVID-19 pandemic on varicella and herpes zoster incidence and health resource use among children in Japan
CONCLUSIONS: Varicella incidence and healthcare resource use were largely affected by the routine immunization program and infection prevention measures against COVID-19, while these impacts on herpes zoster were relatively small. Our study indicates that immunization and infection prevention measures largely changed pediatric infectious disease practices.PMID:37400282 | DOI:10.1016/j.vaccine.2023.06.054
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Kazuhiro Uda Yusuke Okubo Mitsuru Tsuge Hirokazu Tsukahara Isao Miyairi Source Type: research

Necrotizing pancreatitis, microangiopathic hemolytic anemia and thrombocytopenia following the second dose of Pfizer/BioNTech COVID-19 mRNA vaccine
We report a 31-year-old female with a history of borderline personality disorder, intravenous drug abuse, allergic asthma, eating disorder, psoriatic arthritis treated with tofacitinib, neurogenic bladder disturbance, cholecystectomy, recurrent thoracic herpes zoster, vaginal candida infections and urinary tract infections, who developed pancreatitis associated with thrombotic microangiopathy and hemolytic-uremic syndrome 10 days after the second vaccination, whereas the first has been well tolerated. She was treated by plasma exchange, and eventually by transgastric drainage with implantation of a plastic stent to remove ...
Source: Herpes - June 6, 2023 Category: Infectious Diseases Authors: Claudia St öllberger Kastriot Kastrati Clemens Dejaco Martina Scharitzer Josef Finsterer Patrick Bugingo Madeleine Melichart-Kotik Astrid Wilfing Source Type: research

Can the COVID-19 Vaccine Cause Recrudescence of Herpes Zoster Virus While Taking Antiviral Medication?
Cureus. 2023 Apr 24;15(4):e38040. doi: 10.7759/cureus.38040. eCollection 2023 Apr.ABSTRACTCoronavirus disease 2019 (COVID-19) represents a multisystem disease that has caused a devastating global pandemic. The COVID-19 vaccine produced in response to the pandemic has been effective but can have side effects. One well-established condition is the reactivation of herpes zoster (HZ). Various risk factors increase the risk of HZ reactivation such as age, infections, and immunosuppressed states. HZ can have severe complications, including herpes zoster ophthalmicus and postherpetic neuralgia. Here, we present a unique case wher...
Source: Herpes - May 25, 2023 Category: Infectious Diseases Authors: Ameije Ismaili Stefan Anthony Jessica Clark Source Type: research

Clinical characteristics of SARS-CoV-2 vaccine-related acute appendicitis
CONCLUSION: With the exception of older age, the clinical characteristics of patients presenting with acute appendicitis within 21 days of receiving the SARS-CoV-2 vaccination did not differ from those of patients who presented with acute appendicitis not related to the vaccination. This finding suggests that vaccine-related acute appendicitis is similar to "classic" acute appendicitis.PMID:37225246 | DOI:10.1503/cjs.009322
Source: Herpes - May 24, 2023 Category: Infectious Diseases Authors: Elchanan Quint Ivan Kukeev Itai Hazan Daniel Grupel Oleg Dukhno Anton Osyntsov Gilbert Sebbag Ohad Guetta David Czeiger Source Type: research

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