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Early aspirin use after transient ischaemic attack cuts severe stroke risk by 90%
Large analysis of data shows taking aspirin within two weeks of transient ischaemic attack or stroke cuts risk of secondary stroke by over 90%.
Source: Clinical Pharmacist - June 1, 2016 Category: Drugs & Pharmacology Source Type: research

Discontinuing statins after stroke increases risk of another
Stopping statin therapy after ischaemic stroke should be discouraged to avoid increased risk of another stroke.
Source: Clinical Pharmacist - August 21, 2017 Category: Drugs & Pharmacology Source Type: research

Targeting insulin resistance after stroke cuts cardiovascular risk
Large trial shows pioglitazone could reduce risk of cardiovascular events or diabetes in stroke patients
Source: Clinical Pharmacist - February 26, 2016 Category: Drugs & Pharmacology Source Type: research

Well-managed warfarin still useful for stroke prevention
A study of 40,000 patients with atrial fibrillation suggests that warfarin is a valid treatment for stroke prevention.
Source: Clinical Pharmacist - April 27, 2016 Category: Drugs & Pharmacology Source Type: research

Statins effective at preventing first heart attack or stroke
Statins were associated with a 36% lower risk of heart attack and 29% lower risk of stroke compared with placebo in a review of data from more than 70,000 patients.
Source: Clinical Pharmacist - December 19, 2016 Category: Drugs & Pharmacology Source Type: research

Proton pump inhibitors may increase risk of first stroke
Data from 244,679 patients that had undergone endoscopy show that stroke incidence was 19% higher in patients who filed a prescription for a PPI compared with those with no PPI exposure
Source: Clinical Pharmacist - December 29, 2016 Category: Drugs & Pharmacology Source Type: research

Stroke: classification and diagnosis
In light of the many pressures currently facing the NHS, as well as an ever increasing ageing population, pharmacists and healthcare professionals should be aware of the risk factors for stroke, its classification and diagnosis.
Source: Clinical Pharmacist - January 10, 2018 Category: Drugs & Pharmacology Source Type: research

Rheumatoid arthritis drug may reduce inflammation after stroke
The pro-inflammatory cytokine interleukin-1 plays a significant role in brain injury following ischemic stroke by inducing peripheral inflammatory mediators, such as interleukin-6. However, pre-clinical studies show its effects are reduced by the interleukin-1 receptor antagonist.
Source: Clinical Pharmacist - May 14, 2018 Category: Drugs & Pharmacology Source Type: research

Fluoxetine does not assist recovery following stroke, research suggests
Daily fluoxetine in patients who have had a stroke does not improve functional outcomes at six months, results of a randomised trial published in The Lancet have shown.
Source: Clinical Pharmacist - January 21, 2019 Category: Drugs & Pharmacology Source Type: research

Pharmacists in a multidisciplinary atrial fibrillation clinic
Atrial fibrillation (AF) is the most common cardiac rhythm disturbance and increases in prevalence with advancing age. Each year, Tallaght University Hospital in Dublin assesses and admits over 400 patients with stroke and transient ischemic attack. AF is implicated as a causative factor in 33% of these cases. An AF-related stroke is more likely to be fatal, disabling and recurrent than a non-AF related stroke. The risk of AF-related stroke is greatly reduced, however, by early detection ...
Source: Clinical Pharmacist - July 30, 2018 Category: Drugs & Pharmacology Source Type: research

Statins: general safety profile and association with myopathy
Abstract Statin therapy has demonstrated remarkable efficacy in reducing mortalities associated with cardiovascular diseases through preventing myocardial infarction and ischaemic stroke. Despite the proven benefits of statins in this context, there are growing concerns among patients and physicians on the safety of short-term and long-term use and their adverse effects, especially muscle toxicity, resulting in non-adherence and withdrawal of the treatment. ...
Source: Clinical Pharmacist - May 11, 2016 Category: Drugs & Pharmacology Source Type: research

'Don ’t wait to anticoagulate' project
I was interested to read the news story ‘Many atrial fibrillation patients at risk of stroke treated with aspirin over anticoagulants’ (The Pharmaceutical Journal online, 24 June 2016), which outlines the finding that significant numbers of patients with atrial fibrillation (AF) are not being prescribed the most effective form of .. .
Source: Clinical Pharmacist - August 3, 2016 Category: Drugs & Pharmacology Source Type: research

Pharmacist-led atrial fibrillation reviews reduce stroke risk for patients
A review scheme led by a team of pharmacists prevented an estimated 886 strokes in patients with atrial fibrillation.
Source: Clinical Pharmacist - October 31, 2016 Category: Drugs & Pharmacology Source Type: research

Combining statins and antihypertensives boosts stroke prevention
Researchers investigated the efficacy of combined treatment in patients with a risk of cardiovascular diseases
Source: Clinical Pharmacist - February 23, 2018 Category: Drugs & Pharmacology Source Type: research

Uncertainty over anticoagulation risks and benefits in CKD patients with AF
The risk of both stroke and haemorrhage increases as chronic kidney disease progresses, which can complicate the decision on whether to begin anticoagulation in those with concomitant atrial fibrillation.
Source: Clinical Pharmacist - March 28, 2018 Category: Drugs & Pharmacology Source Type: research

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