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Exact Basilar Artery Occlusion Location Indicates Stroke Etiology and Recanalization Success in Patients Eligible for Endovascular Stroke Treatment
ConclusionThe exact basilar artery occlusion site in patients eligible for endovascular stroke treatment reflects the stroke etiology and is associated with differing recanalization success but does not predict favorable clinical outcome.
Source: Klinische Neuroradiologie - December 2, 2022 Category: Radiology Source Type: research

Intracranial Spotty Calcium Predicts Recurrent Stroke in Patients with Symptomatic Intracranial Atherosclerotic Stenosis
ConclusionIn patients with symptomatic ICAS, intracranial spotty calcium is an independent predictor of recurrent ischemic stroke, which will further facilitate risk stratification and suggest that more aggressive treatment should be considered for these patients.
Source: Klinische Neuroradiologie - June 7, 2023 Category: Radiology Source Type: research

Associations Between Diffusion Dynamics and Functional Outcome in Acute and Early Subacute Ischemic Stroke
ConclusionDiffusion dynamics are correlated with the clinical functional outcome of ischemic stroke. This correlation is independent of the effect of lesion volume and is specific to the time period between symptom onset and imaging. More effort is needed to further investigate the predictive value of diffusion-weighted imaging.
Source: Klinische Neuroradiologie - August 8, 2019 Category: Radiology Source Type: research

Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
ConclusionThese results confirm prior studies stating that DA to a  comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.
Source: Klinische Neuroradiologie - October 10, 2019 Category: Radiology Source Type: research

Patterns of Visual Task-based Functional MRI Activation in Chronic Posterior Cerebral Artery Stroke Patients
ConclusionIn chronic PCA stroke patients with residual visual impairments, the brain attempts to recruit more neighboring and distant functional areas for executing the impaired visual skill. This intense recruitment pattern in poorly recovering patients appears to be a  sign of failed compensation. Consequently, fMRI has the potential for clinically relevant prognostic assessment in patients surviving PCA stroke; however, as this study included no longitudinal data, this potential should be further investigated in longitudinal imaging studies, with a larger coho rt, and multiple time points.
Source: Klinische Neuroradiologie - March 3, 2023 Category: Radiology Source Type: research

Accuracy and Prognostic Role of NCCT-ASPECTS Depend on Time from Acute Stroke Symptom-onset for both Human and Machine-learning Based Evaluation
ConclusionThe accuracy and reliability of NCCT-ASPECTS are time dependent for both human and machine-learning based evaluation, indicating reduced detectability of fast stroke progressors by NCCT. In hyperacute stroke, collateral status from CT-angiography may help for a  better prognosis on clinical outcome and explain the occurrence of futile recanalization.
Source: Klinische Neuroradiologie - October 28, 2021 Category: Radiology Source Type: research

Reasons for Failed Mechanical Thrombectomy in Posterior Circulation Ischemic Stroke Patients
ConclusionFailure of MT in posterior circulation ischemic stroke patients is associated with a  high mortality rate. Reasons for MT failure are diverse with futile vascular access and MT failure after passing the vessel occlusion as the leading causes. Alternative vascular access, local i.a. thrombolysis and stent-assisted PTA can prevent MT failure.
Source: Klinische Neuroradiologie - September 6, 2020 Category: Radiology Source Type: research

Clinical Impact and Predictors of Diffusion Weighted Imaging  (DWI) Reversal in Stroke Patients with Diffusion Weighted Imaging Alberta Stroke Program Early CT Score 0–5 Treated by Thrombectomy
ConclusionThe DWI reversal occurs in a  non-negligible proportion of DWI-ASPECTS 0–5 patients subjected to thrombectomy and significantly influences clinical outcome. The mTICI 2c–3 recanalization emerged as an independent DWIr predictor.
Source: Klinische Neuroradiologie - April 12, 2022 Category: Radiology Source Type: research

Meniscus Sign in Patients with Anterior Circulation Large Vessel Occlusion Stroke does not Predict Outcome
ConclusionThe presence of MS in acute ischemic stroke patients with anterior circulation large vessel occlusion who undergo EVT does not appear to influence angiographic or clinical outcomes.
Source: Klinische Neuroradiologie - June 24, 2022 Category: Radiology Source Type: research

Mechanical Thrombectomy —A Brief Review of a Revolutionary new Treatment for Thromboembolic Stroke
AbstractThe recent success of endovascular stroke treatment has heralded a  new era in the management of acute ischemic stroke (AIS) with significantly improved outcome for patients. A large number of patients may be amenable to this new treatment and as the evidence expands the number of patients eligible for mechanical thrombectomy continues to increase. Recent evidenc e suggests that the time window for treatment can be extended up to 24 h after symptom onset for patients with anterior circulation strokes; however, many clinicians and medical professionals may not be aware of these recent changes and it is important...
Source: Klinische Neuroradiologie - May 9, 2018 Category: Radiology Source Type: research

Time to Endovascular Reperfusion and Outcome in Acute Ischemic Stroke
ConclusionAmong patients with acute ischemic stroke in routine clinical practice, shorter time to reperfusion was associated with better outcome after endovascular therapy. Standardized workflows and training in endovascular treatment techniques should be promoted nationally to reduce in-hospital delays.
Source: Klinische Neuroradiologie - May 27, 2022 Category: Radiology Source Type: research

Outcome of Stroke Patients with Unknown Onset and Unknown Time Last Known Well Undergoing Endovascular Therapy
ConclusionThe LKWu patients had a  similar outcome after ET as KO and LKWk patients after adjusting for confounders. Thus, ET should not be withheld if the time last known well is unknown. Instead, LKWu patients may be selected for ET using the same criteria as in LKWk patients.
Source: Klinische Neuroradiologie - July 7, 2022 Category: Radiology Source Type: research

Dual-Energy Computed Tomography in Stroke Imaging
ConclusionTwinSpiral DECT allows an improved qualitative and quantitative visualization of ischemic brain tissue in ischemic stroke patients after endovascular treatment.
Source: Klinische Neuroradiologie - March 2, 2023 Category: Radiology Source Type: research

Distinct Alterations in Oxygenation, Ion Composition and Acid-Base Balance in Cerebral Collaterals During Large-Vessel Occlusion Stroke
ConclusionThese findings suggest that stroke-induced changes in oxygen supply, ion composition and acid-base balance occur and dynamically progress within penumbral areas during human cerebral ischemia and are related to acute tissue damage.
Source: Klinische Neuroradiologie - June 7, 2023 Category: Radiology Source Type: research

Internal Carotid Artery Stenosis and Collateral Recruitment in Stroke Patients
ConclusionNo association was found between pre-existing ICA stenosis and extent of CTP derived collateral filling in patients with an M1  occlusion.
Source: Klinische Neuroradiologie - April 24, 2017 Category: Radiology Source Type: research

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