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Source: Experimental and Therapeutic Medicine

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Total 541 results found since Jan 2013.

Efficacy and safety of unilateral biportal endoscopy compared with microscopic decompression in the treatment of lumbar spinal stenosis: A systematic review and updated meta ‑analysis
Exp Ther Med. 2023 May 10;26(1):309. doi: 10.3892/etm.2023.12008. eCollection 2023 Jul.ABSTRACTThe incidence of lumbar spinal stenosis is increasing annually, and with an ever-aging population and longer life expectancies, this trend will further continue. It is hoped that a more effective treatment can be found so that the patients can be relieved of their pain. The aim of this systematic review and meta-analysis was to evaluate the effectiveness and safety of unilateral biportal endoscopic surgery (UBE) and microscopic decompression surgery (MD) for the treatment of lumbar spinal stenosis. A literature search of related ...
Source: Experimental and Therapeutic Medicine - June 5, 2023 Category: General Medicine Authors: Yue-Peng Wang Shi-Lei Qin Su Yang Yun-Feng Xu Peng-Fei Han Source Type: research

SPTBN2 regulates endometroid ovarian cancer cell proliferation, invasion and migration via ITGB4 ‑mediated focal adhesion and ECM receptor signalling pathway
Exp Ther Med. 2023 Apr 24;25(6):277. doi: 10.3892/etm.2023.11977. eCollection 2023 Jun.ABSTRACTOvarian cancer is as a major contributor to gynaecologic death globally. The present study aimed to investigate the regulatory role of spectrin β non-erythrocytic 2 gene (SPTBN2) in endometroid ovarian cancer and its mechanism of action. According to the Gene Expression Profiling Interactive Analysis (GEPIA) database, SPTBN2 expression is elevated in ovarian cancer tissues and higher SPTBN2 expression indicated a worse prognosis. The present study assessed SPTBN2 mRNA and protein expression levels by reverse transcription-quanti...
Source: Experimental and Therapeutic Medicine - May 19, 2023 Category: General Medicine Authors: La Yang Yuanyuan Gu Source Type: research

Lactate dehydrogenase and aspartate aminotransferase levels associated with the severity of COVID ‑19: A systematic review and meta‑analysis
Exp Ther Med. 2023 Mar 29;25(5):221. doi: 10.3892/etm.2023.11920. eCollection 2023 May.ABSTRACTLactate dehydrogenase (LDH) and aspartate aminotransferase (AST) are important indicators of cardiovascular, muscle and liver lesions, and can be used as prognostic indicators for infectious diseases, such as coronavirus disease 2019 (COVID-19). The present systematic review and meta-analysis assessed the prognostic value of LDH and AST levels for COVID-19 severity. Ovid-Medline, PubMed, Embase and The Cochrane Library were used to search for articles, according to the inclusion and exclusion criteria, until July 2022. The meta-a...
Source: Experimental and Therapeutic Medicine - May 1, 2023 Category: General Medicine Authors: Ziyun He Rengqin Yan Jinsong Liu Haibing Dai Yonglin Zhu Feng Zhang Lin Zhang Shengkai Yan Source Type: research