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Thrombectomy vs. medical management for large vessel occlusion strokes with minimal symptoms
Exp Ther Med. 2023 Jun 23;26(2):377. doi: 10.3892/etm.2023.12076. eCollection 2023 Aug.ABSTRACTPatients with acute ischemic stroke (AIS) presenting mild symptoms with a low National Institutes of Health Stroke Scale (NIHSS) score ≤8 and also found to have an intracranial large vessel occlusion (LVO) undergo endovascular thrombolysis (ET) or medical management alone. The current study aimed to evaluate the safety and effectiveness of medical management vs. ET therapy among patients with mild AIS symptoms (NIHSS score ≤8) accompanied by LVO. The present meta-analysis included articles involving mild AIS, LVO, thrombectom...
Source: Experimental and Therapeutic Medicine - July 17, 2023 Category: General Medicine Authors: Iason-Stefanos Anagnostopoulos Vasiliki Epameinondas Georgakopoulou Ilias Trakas Petros Papalexis Nikolaos Trakas Demetrios A Spandidos George Fotakopoulos Source Type: research

Genetic associations between miR ‑200bT & gt;C and miR ‑495A & gt;C polymorphisms and hypertension susceptibility
Exp Ther Med. 2023 May 31;26(1):353. doi: 10.3892/etm.2023.12052. eCollection 2023 Jul.ABSTRACTAlthough microRNA (miRNA)-mediated functions and gene expression regulation are involved in the susceptibility to vascular diseases, the potential effect of miRNA polymorphisms on the susceptibility of patients to hypertension (HTN) remains to be sufficiently elucidated. Therefore, the present study aimed to identify the potential association between miRNA (miR)-200bT>C (rs7549819) and miR-495A>C (rs2281611) polymorphisms, which may be implicated in stroke and vascular pathogenesis, and the susceptibility to HTN and relevan...
Source: Experimental and Therapeutic Medicine - June 16, 2023 Category: General Medicine Authors: Youngmi Choi Seung-Ho Hong Source Type: research

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