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Updated Trans-Ethnic Meta-Analysis of Associations between Inflammation-Related Genes and Intracranial Aneurysm
CONCLUSION: Our updated meta-analysis with increased statistical power highlights that rs1800796 which maps on the IL-6 gene is associated with IA, and in particular confers a protective effect against occurrence of IA in the East-Asian population.PMID:37068789 | DOI:10.3340/jkns.2023.0001
Source: Journal of Korean Neurosurgical Society - April 17, 2023 Category: Neurosurgery Authors: Eun Pyo Hong Sung Min Cho Jong Kook Rhim Jeong Jin Park Jun Hyong Ahn Dong Hyuk Youn Jong-Tae Kim Chan Hum Park Younghyurk Lee Jin Pyeong Jeon First Korean Stroke Genetics Association Research (The FirstKSGAR) Study Source Type: research

Recanalization Rate and Clinical Outcomes of Intravenous Tissue Plasminogen Activator Administration for Large Vessel Occlusion Stroke Patients
CONCLUSION: The P/D-mismatching influences on the recanalization and clinical outcomes of IV-tPA and IA-Tx. The authors would like to propose that we had better prepare IA-Tx when LVO is diagnosed on initial diagnostic imaging. Furthermore, if the patient shows P/D-mismatching on MRA after IV-tPA, additional IA-Tx improves treatment results and lessen the futile recanalization.PMID:36825298 | DOI:10.3340/jkns.2022.0120
Source: Journal of Korean Neurosurgical Society - February 24, 2023 Category: Neurosurgery Authors: Min-Hyung Lee Sang-Hyuk Im Kwang Wook Jo Do-Sung Yoo Source Type: research

Early Restoration of Hypoperfusion Confirmed by Perfusion Magnetic Resonance Image after Emergency Superficial Temporal Artery to Middle Cerebral Artery Anastomosis
CONCLUSION: In a patient who had an acute cerebral infarction due to large vessel occlusion with large ischemic penumbra but was unable to perform mechanical thrombectomy, STA-MCA bypass could be performed. By using time-to-peak images of perfusion MRI, it is possible to quickly and easily confirm that the brain tissue at risk is preserved and that the ischemic penumbra is recovered to a normal blood flow state.PMID:36069027 | DOI:10.3340/jkns.2022.0100
Source: Journal of Korean Neurosurgical Society - September 7, 2022 Category: Neurosurgery Authors: Jin Eun Ik Seong Park Source Type: research

Role of Neurosurgeons in the Treatment of Acute Ischemic Stroke in the Emergency Room
CONCLUSION: The neurosurgeon group showed similar door-to-treatment time and clinical outcomes to the neurologist group in patients with AIS in the ER. This study suggests that neurosurgeons have comparable abilities to care for patients with AIS in the ER.PMID:35974432 | DOI:10.3340/jkns.2022.0085
Source: Journal of Korean Neurosurgical Society - August 17, 2022 Category: Neurosurgery Authors: Sang Hyuk Lee Taek Min Nam Ji Hwan Jang Young Zoon Kim Kyu Hong Kim Kyeong Hwa Ryu Do-Hyung Kim Byung Soo Kwan Hyungon Lee Seung Hwan Kim Source Type: research

Identification of hub Genes in the Pathogenesis of Ischemic Stroke Based on Bioinformatics Analysis
CONCLUSION: 36 DEGs, 5 Hub genes and 3 miRNA were obtained from bioinformatics analysis of IS microarray data, which might provide potential targets for diagnosis and treatment of IS.PMID:35577542 | DOI:10.3340/jkns.2021.0200
Source: Journal of Korean Neurosurgical Society - May 16, 2022 Category: Neurosurgery Authors: Xitong Yang Shanquan Yan Pengyu Wang Guangming Wang Source Type: research

The Kernohan-Woltman Notch Phenomenon : A Systematic Review of Clinical and Radiologic Presentation, Surgical Management, and Functional Prognosis
J Korean Neurosurg Soc. 2022 May 16. doi: 10.3340/jkns.2022.0002. Online ahead of print.ABSTRACTThe Kernohan-Woltman notch phenomenon (KWNP) refers to an intracranial lesion causing massive side-to-side mass effect which leads to compression of the contralateral cerebral peduncle against the free edge of the cerebellar tentorium. Diagnosis is based on "paradoxical" motor deficit ipsilateral to the lesion associated with radiologic evidence of damage to the contralateral cerebral peduncle. To date, there is scarce evidence regarding KWNP associated neuroimaging patterns and motor function prognostic factors. A systematic re...
Source: Journal of Korean Neurosurgical Society - May 16, 2022 Category: Neurosurgery Authors: Nathan Beucler Pierre-Julien Cungi Guillaume Baucher St éphanie Coze Arnaud Dagain Pierre-Hugues Roche Source Type: research

Identification of hub Genes in the Pathogenesis of Ischemic Stroke Based on Bioinformatics Analysis
CONCLUSION: 36 DEGs, 5 Hub genes and 3 miRNA were obtained from bioinformatics analysis of IS microarray data, which might provide potential targets for diagnosis and treatment of IS.PMID:35577542 | DOI:10.3340/jkns.2021.0200
Source: Journal of Korean Neurosurgical Society - May 16, 2022 Category: Neurosurgery Authors: Xitong Yang Shanquan Yan Pengyu Wang Guangming Wang Source Type: research

The Kernohan-Woltman Notch Phenomenon : A Systematic Review of Clinical and Radiologic Presentation, Surgical Management, and Functional Prognosis
J Korean Neurosurg Soc. 2022 May 16. doi: 10.3340/jkns.2022.0002. Online ahead of print.ABSTRACTThe Kernohan-Woltman notch phenomenon (KWNP) refers to an intracranial lesion causing massive side-to-side mass effect which leads to compression of the contralateral cerebral peduncle against the free edge of the cerebellar tentorium. Diagnosis is based on "paradoxical" motor deficit ipsilateral to the lesion associated with radiologic evidence of damage to the contralateral cerebral peduncle. To date, there is scarce evidence regarding KWNP associated neuroimaging patterns and motor function prognostic factors. A systematic re...
Source: Journal of Korean Neurosurgical Society - May 16, 2022 Category: Neurosurgery Authors: Nathan Beucler Pierre-Julien Cungi Guillaume Baucher St éphanie Coze Arnaud Dagain Pierre-Hugues Roche Source Type: research

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