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Source: Asian Pacific Journal of Cancer Prevention

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Total 1205 results found since Jan 2013.

In Search for a Common Pathway for Health Issues in Men - the Sign of a Holmesian Deduction.
Authors: Aoun F, Albisinni S, Chemaly AK, Zanaty M, Roumeguere T Abstract The evidence for the existence of a common pathway for health issues in men is presented in this review. Several epidemiological studies have shown that conditions like cardiovascular diseases (CVD), metabolic syndrome, diabetes, lower urinary tract symptom (LUTS), erectile dysfunction (ED), prostate cancer, hypogonadism, depression and suicide can be associated as risk factors for each other. Thus, the risk of CVD is significantly increased in men with metabolic syndrome, ED, hypogonadism, prostate cancer and/or LUTS. In addition, the above ...
Source: Asian Pacific Journal of Cancer Prevention - February 5, 2016 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Telomerase as a Possible Candidate Targeting Therapy in Different Breast Cancer Cell Lines.
CONCLUSION: Telomerase inhibition is a promising strategy for the effective treatment of breast cancer. When used in combination with doxorubicin, it could potentiate the cytotoxic effect of the drug on breast cancer cells.<br />. PMID: 32856851 [PubMed - as supplied by publisher]
Source: Asian Pacific Journal of Cancer Prevention - August 29, 2020 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Characterization of Apoptosis in a Breast Cancer Cell Line after IL-10 Silencing
Conclusions: In conclusion, the production of IL-10 may represent a new escape mechanism by breast cancer cells to evade destruction by the immune system. IL-10 gene silencing causes down regulation of both PI3K/AKT and Bcl2 gene expression and also increases the Bbc3, BAX caspase3, and caspase 3 cleavage expression levels. IL–10 might represent a promising new target for therapeutic strategies. PMID: 29582634 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Gene Silencing of TGF βRII Can Inhibit Glioblastoma Cell Growth
Conclusion: Our results suggest that TGFβ RII silencing can be a promising complementary treatment for glioma. PMID: 30256570 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - September 28, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Dual Targeting of Anti-Apoptotic Proteins Enhances Chemosensitivity of the Acute Myeloid Leukemia Cells
CONCLUSIONS: Our investigation suggests that suppression of Mcl-1 and survivin by siRNA can effectually inhibit cell growth and overcome chemoresistance of AML cells. Therefore siRNAs may be an important adjuvant in chemotherapy for AML patients.PMID:35901361 | DOI:10.31557/APJCP.2022.23.7.2523
Source: Asian Pacific Journal of Cancer Prevention - July 28, 2022 Category: Cancer & Oncology Authors: Behzad Baradaran Roya Nazmabadi Zohreh Ariyan Ebrahim Sakhinia Hadi Karami Source Type: research