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Coronary In-Stent Restenosis –Predictors and Treatment
CONCLUSION: Because the pathogenesis of ISR is multifactorial, differentiated risk stratification is necessary. The identification of patient-, stent-, and lesion-related predictors is particularly important, as the most effective way to combat ISR is to prevent it.PMID:34379053 | DOI:10.3238/arztebl.m2021.0254
Source: Deutsches Arzteblatt International - August 11, 2021 Category: General Medicine Authors: Helen Ullrich Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research

Coronary In-Stent Restenosis-Predictors and Treatment
CONCLUSION: Because the pathogenesis of ISR is multifactorial, differentiated risk stratification is necessary. The identification of patient-, stent-, and lesion-related predictors is particularly important, as the most effective way to combat ISR is to prevent it.PMID:34379053 | DOI:10.3238/arztebl.m2021.0254
Source: Deutsches Arzteblatt International - August 11, 2021 Category: General Medicine Authors: Helen Ullrich Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research

Inhibition of Platelet Aggregation After Coronary Stenting in Patients Receiving Oral Anticoagulation
CONCLUSION: After coronary stent implantation, dual therapy with a NOAC and a P2Y12 inhibitor is recommended, subsequent to triple therapy given only during the peri-interventional period.PMID:33637173 | DOI:10.3238/arztebl.m2021.0150
Source: Deutsches Arzteblatt International - February 27, 2021 Category: General Medicine Authors: Conrad Genz Ruediger C Braun-Dullaeus Source Type: research

Tranexamic Acid Prophylaxis in Hip and Knee Joint Replacement.
CONCLUSION: The prophylactic intravenous administration of tranexamic acid lessens the amount of bleeding in endoprosthetic knee and hip procedures and reduces the likelihood of blood transfusion. According to the current state of the evidence, complications are rare. Nonetheless, consideration of the risks and benefits implies that tranexamic acid should not be given for this purpose to patients who have recently had urogenital bleeding, pulmonary embolism, or a myocardial infarction, who have recently undergone percutaneous transluminal coronary angioplasty or stenting, or who are known to have epilepsy. PMID: 292492...
Source: Deutsches Arzteblatt International - December 20, 2017 Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research

The Treatment of Post-Thrombotic Syndrome.
CONCLUSION: All conservative options should be exhausted as the first line of treatment. If PTS symptoms persist and markedly impair the patient's quality of life, the possible indication for surgery should be considered. As PTS hardly ever leads to death or limb loss, its treatment should be as uninvasive as possible. Endovascular recanalization is an attractive option in this respect. A conclusive evaluation of the role of endovascular procedures in PTS must await randomized trials of this form of treatment and of the optimal stent configuration. PMID: 28098065 [PubMed - in process]
Source: Deutsches Arzteblatt International - January 19, 2017 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research