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Diseases of the Coronary Microcirculation: Diagnosis and Treatment
CONCLUSION: Approximately 25% of patients with CMD have symptoms that do not respond to intensive treatment with the currently available modalities. New treatments, including interventional therapies, are being studied. Their long-term benefit remains to be assessed and compared to that of the existing methods.PMID:37721132 | DOI:10.3238/arztebl.m2023.0205
Source: Deutsches Arzteblatt International - September 18, 2023 Category: General Medicine Authors: Helen Ullrich-Daub Steffen Daub Maximilian Olschewski Thomas M ünzel Tommaso Gori Source Type: research

Meralgia Paresthetica: Relevance, Diagnosis, and Treatment
CONCLUSION: The state of the evidence is limited in both quantity and quality, corresponding to evidence level 2a for surgical and non-surgical methods. Advances in imaging and neurophysiological testing have made the diagnosis easier to establish. When intervention is needed, good success rates have been achieved with surgery (decompression, neurectomy), and variable success rates with infiltration.PMID:37534445 | DOI:10.3238/arztebl.m2023.0170
Source: Deutsches Arzteblatt International - August 3, 2023 Category: General Medicine Authors: Christoph Scholz Marc Hohenhaus Maria Teresa Pedro Anne-Kathrin Uerschels Nora F Dengler Source Type: research

The Multimodal Treatment of Rectal Cancer
CONCLUSION: The treatment of rectal cancer is a prime example of an interdisciplinary, multimodal approach. In the past, the focus was mainly on improving oncologic outcomes; at present, increasing attention is being devoted to the patients' quality of life as well and the functional aspects of the various modes of treatment.PMID:35791271 | DOI:10.3238/arztebl.m2022.0254
Source: Deutsches Arzteblatt International - July 6, 2022 Category: General Medicine Authors: Michael Ghadimi Claus R ödel Ralf Hofheinz Hannah Flebbe Marian Grade Source Type: research

Focal Radiotherapy of Brain Metastases in Combination With Immunotherapy and Targeted Drug Therapy
CONCLUSION: Brain metastases should be treated by a multidisciplinary team, so that the optimal sequence of local and systemic therapies can be determined for each individual patient.PMID:34730083 | DOI:10.3238/arztebl.m2021.0332
Source: Deutsches Arzteblatt International - November 3, 2021 Category: General Medicine Authors: David Kaul Anna Sophie Berghoff Anca-Ligia Grosu Carolin Weiss Lucas Matthias Guckenberger Source Type: research

Imaging of Prostate Cancer
CONCLUSION: The appropriate use of mpMRI and MR/TRUS fusion biopsy improves the initial detection of prostate cancer as well as the assessment of the prognosis. PSMA hybrid imaging is useful for the staging of high-risk patients and for the detection of recurrences. These methods are now recommended in the German clinical practice guideline on prostate cancer as well as in guidelines from other countries.PMID:34427180 | DOI:10.3238/arztebl.m2021.0309
Source: Deutsches Arzteblatt International - August 24, 2021 Category: General Medicine Authors: Heinz-Peter Schlemmer Bernd Joachim Krause Viktoria Sch ütz David Bonekamp Sarah Schwarzenb öck Markus Hohenfellner Source Type: research

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