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Specialty: Molecular Biology
Source: Molecular Medicine Reports
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Total 175 results found since Jan 2013.
Apolipoprotein E mimetic peptide COG1410 alleviates blood ‑brain barrier injury in a rat model of ischemic stroke
In conclusion, the data suggest that COG1410 can alleviate BBB injury and neuroinflammation following ischemic stroke.PMID:36866740 | DOI:10.3892/mmr.2023.12972
Source: Molecular Medicine Reports - March 3, 2023 Category: Molecular Biology Authors: Yunwen Xue Minhua Gu Cuilan Chen Yujian Yao Yuzhen Li Guohu Weng Yong Gu Source Type: research
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4 ‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury
Mol Med Rep. 2023 Jan;27(1):9. doi: 10.3892/mmr.2022.12896. Epub 2022 Nov 11.ABSTRACT3,4‑Dihydroxybenzaldehyde (DBD), one of the active components of Gastrodia elata, has a cerebral protective effect and can effectively combat cerebral ischemia/reperfusion (I/R) injury in rats. However, the metabolite profiles and underlying mechanisms associated with DBD remain unclear. To explore the level of energy metabolism and pharmacological targets in brain tissue following DBD treatment of stroke. The right middle cerebral artery of the rats was occluded for 2 h and reperfused for 24 h to simulate brain I/R injury. Pharmacologic...
Source: Molecular Medicine Reports - November 11, 2022 Category: Molecular Biology Authors: Yuan Luo Pu Chen Liping Yang Xiaohua Duan Source Type: research
Antihypertension effect of astragaloside IV during cerebral ischemia reperfusion in rats
In conclusion, astragaloside IV may alleviate CIR injury partially by lowering systemic blood pressure.PMID:36331022 | DOI:10.3892/mmr.2022.12890
Source: Molecular Medicine Reports - November 4, 2022 Category: Molecular Biology Authors: Fengyan Shen Yong Meng Yuhai He Bowan Huang Jinxin Huang Lu Wang Source Type: research
