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Molecules, Vol. 24, Pages 4222: Bixa orellana L. (Bixaceae) and Dysphania ambrosioides (L.) Mosyakin & amp; Clemants (Amaranthaceae) Essential Oils Formulated in Nanocochleates against Leishmania amazonensis
Molecules, Vol. 24, Pages 4222: Bixa orellana L. (Bixaceae) and Dysphania ambrosioides (L.) Mosyakin & Clemants (Amaranthaceae) Essential Oils Formulated in Nanocochleates against Leishmania amazonensis Molecules doi: 10.3390/molecules24234222 Authors: Laura Machín Beatriz Tamargo Abel Piñón Regla C. Atíes Ramón Scull William N. Setzer Lianet Monzote Leishmaniasis is a group of neglected tropical diseases caused by protozoan parasites of the Leishmania genus. The absence of effective vaccines and the limitations of current treatments make the search for effective therapies a real need. Diff...
Source: Molecules - November 19, 2019 Category: Chemistry Authors: Laura Mach ín Beatriz Tamargo Abel Pi ñón Regla C. At íes Ram ón Scull William N. Setzer Lianet Monzote Tags: Article Source Type: research

Molecules, Vol. 23, Pages 1451: Protein Carriers for Glycoconjugate Vaccines: History, Selection Criteria, Characterization and New Trends
ntino Currently licensed glycoconjugate vaccines are composed of a carbohydrate moiety covalently linked to a protein carrier. Polysaccharides are T-cell independent antigens able to directly stimulate B cells to produce antibodies. Disease burden caused by polysaccharide-encapsulated bacteria is highest in the first year of life, where plain polysaccharides are not generally immunogenic, limiting their use as vaccines. This limitation has been overcome by covalent coupling carbohydrate antigens to proteins that provide T cell epitopes. In addition to the protein carriers currently used in licensed glycoconjugate vacci...
Source: Molecules - June 15, 2018 Category: Chemistry Authors: Francesca Micoli Roberto Adamo Paolo Costantino Tags: Review Source Type: research