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Development and validation of a nomogram for the risk prediction of malignant cerebral edema after acute large hemispheric infarction involving the anterior circulation
ConclusionOur nomogram based on LASSO-logistic regression is accurate and useful for the early prediction of MCE after LHI. This model can serve as a precise and practical tool for clinical decision-making in patients with LHI who may require aggressive therapeutic approaches.
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

Impact of e-ASPECTS software on the performance of physicians compared to a consensus ground truth: a multi-reader, multi-case study
ConclusionDecision support with the e-ASPECTS software significantly improves the accuracy of ASPECTS scoring, even by expert US neurologists and neuroradiologists.
Source: Frontiers in Neurology - September 7, 2023 Category: Neurology Source Type: research

Combining convolutional attention mechanism and residual deformable Transformer for infarct segmentation from CT scans of acute ischemic stroke patients
ConclusionThe strong correlation between the infarct segmentation obtained via our method and the ground truth allows us to conclude that our method could accurately segment infarcts from NCCT images.
Source: Frontiers in Neurology - July 20, 2023 Category: Neurology Source Type: research

Improving door-to-reperfusion time in acute ischemic stroke during the COVID-19 pandemic: experience from a public comprehensive stroke center in Brazil
ConclusionAcute stroke care continued to be a priority despite the COVID-19 pandemic. The implementation of a thrombolytic bolus and the start of continuous infusion on the CT scan table was the main factor that contributed to the reduction of DNT. Continuous monitoring of service times is essential for improving the quality of the stroke center and achieving better functional outcomes for patients.
Source: Frontiers in Neurology - July 10, 2023 Category: Neurology Source Type: research

Connectomic insight into unique stroke patient recovery after rTMS treatment
This study demonstrates for the first time the feasibility of using individualized connectivity analyses in differentiating unique phenotypes in rTMS treatment responses and recovery. This personalized connectomic approach may be utilized in the future to better understand patient recovery trajectories with neuromodulatory treatment.
Source: Frontiers in Neurology - July 6, 2023 Category: Neurology Source Type: research

A brain CT-based approach for predicting and analyzing stroke-associated pneumonia from intracerebral hemorrhage
DiscussionOur findings suggest that our method is effective in classifying the development of pneumonia based on brain CT scans. Furthermore, we identified distinct characteristics, such as volume and distribution, of ICH in four different types of SAP.
Source: Frontiers in Neurology - June 2, 2023 Category: Neurology Source Type: research

Scalp acupuncture regulates functional connectivity of cerebral hemispheres in patients with hemiplegia after stroke
ConclusionThe changes in functional connectivity between the cerebral cortex and basal ganglia in patients with cerebral infarction showed a weakening of the bilateral hemispheres and the enhancement of the connections between the hemispheres. Scalp acupuncture has the function of bidirectional regulation, which makes the unbalanced abnormal brain function state restore balance.
Source: Frontiers in Neurology - May 25, 2023 Category: Neurology Source Type: research

Validation of two automated ASPECTS software on non-contrast computed tomography scans of patients with acute ischemic stroke
ConclusionAutomated ASPECTS showed good reliability and 5 mm was the optimal slice thickness.
Source: Frontiers in Neurology - April 6, 2023 Category: Neurology Source Type: research

The diagnostic value of quantitative parameters on dual-layer detector-based spectral CT in identifying ischaemic stroke
ConclusionThe study showed the spectral CT would be a potential novel rapid method for identifying AIS. The spectral CT quantitative parameters (Zeff, iodine density values, and iodine–no-water values) can effectively differentiate the ischaemic area from non-ischaemic tissue in stroke patients.
Source: Frontiers in Neurology - February 23, 2023 Category: Neurology Source Type: research

Bilateral ankle deformities affects gait kinematics in chronic stroke patients
ConclusionUsing 3D scanning technology, bilateral morphometric changes in the feet of chronic stroke patients were shown by GMM and the simple anthropometric measurements identified its shape deformities in the feet. Their possible effects on gait kinematics while walking on uneven terrains were investigated. Current methodology can be potentially useful in applying conventional productions of clinically manufactured, patient-fitted ankle-foot-orthosis in orthotics and prosthetics, and in detecting various unidentified pathological deformities in the feet.
Source: Frontiers in Neurology - February 9, 2023 Category: Neurology Source Type: research

Automated quantification of atrophy and acute ischemic volume for outcome prediction in endovascular thrombectomy
ConclusionCombinations of automated software-based imaging analysis and clinical data can be useful for predicting short-term neurological outcome and may improve long-term prognostication in EVT. These results provide a basis for future development of predictive tools built into decision-aiding software in stroke.
Source: Frontiers in Neurology - December 15, 2022 Category: Neurology Source Type: research

Stroke systems of care in the Philippines: Addressing gaps and developing strategies
In the Philippines, the mortality from stroke during the last 10 years remains high. This paper aims to describe the gaps in stroke care and the development of stroke systems of care in the Philippines. Gaps in stroke systems of care include low number of neurologist, inadequate CT scan machines, lack of stroke training among health workers, lack of stroke protocols and pathways, poor community stroke awareness, low government insurance coverage with high out of pocket medical expenses, lack of infrastructure for EMS, inadequate acute stroke ready hospitals, stroke units and rehabilitation facilities. Although there are go...
Source: Frontiers in Neurology - November 24, 2022 Category: Neurology Source Type: research

Heart rate variability is associated with cerebral small vessel disease in patients with diabetes
ConclusionsLower HRV was associated with total burden of CSVD and each MRI markers of CSVD separately among diabetic patients, but not among non-diabetic patients.
Source: Frontiers in Neurology - November 10, 2022 Category: Neurology Source Type: research

The impact of COVID-19 pandemic on treatment delay and short-term neurological functional prognosis for acute ischemic stroke during the lockdown period
ConclusionThe COVID-19 pandemic has had remarkable impacts on the management of AIS. The pandemic might exacerbate certain time delays and play a significant role in early adverse outcomes in patients with AIS.
Source: Frontiers in Neurology - October 20, 2022 Category: Neurology Source Type: research

Risk factors of late lesion growth after acute ischemic stroke treatment
ConclusionLate, subacute, lesion growth occurring between 1 day and 1 week after ischemic stroke treatment is influenced by lower collateral capacity, longer time to treatment, unsuccessful recanalization, and larger midline shift. Notably, these risk factors are similar to the risk factors of acute lesion growth, suggesting that understanding and minimizing the effects of the predictors for late lesion growth could be beneficial to mitigate the effects of ischemia.
Source: Frontiers in Neurology - October 5, 2022 Category: Neurology Source Type: research

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