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Non-motor complications in late stage Parkinson's disease: recognition, management and unmet needs.
Authors: Rukavina K, Batzu L, Boogers A, Abundes-Corona A, Bruno V, Chaudhuri KR Abstract Introduction: The burden of non-motor symptoms (NMS) is a major determinant of health-related quality of life in Parkinson's disease (PD), particularly at its late stage. Areas covered: The late stage is usually defined as the period from unstable advanced to the palliative stage, characterized by a combination of an emerging treatment-resistant axial motor symptoms (freezing of gait, postural instability, falls and dysphagia), as well as both non-dopaminergic and dopaminergic NMS: cognitive decline, neuropsychiatric symptoms, as...
Source: Expert Review of Neurotherapeutics - February 2, 2021 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Non-motor complications in late stage Parkinson's disease: recognition, management and unmet needs
Expert Rev Neurother. 2021 Feb 16:1-18. doi: 10.1080/14737175.2021.1883428. Online ahead of print.ABSTRACTIntroduction: The burden of non-motor symptoms (NMS) is a major determinant of health-related quality of life in Parkinson's disease (PD), particularly at its late stage. Areas covered: The late stage is usually defined as the period from unstable advanced to the palliative stage, characterized by a combination of emerging treatment-resistant axial motor symptoms (freezing of gait, postural instability, falls and dysphagia), as well as both non-dopaminergic and dopaminergic NMS: cognitive decline, neuropsychiatric symp...
Source: Expert Review of Neurotherapeutics - February 1, 2021 Category: Neurology Authors: Katarina Rukavina Lucia Batzu Alexandra Boogers Arturo Abundes-Corona Veronica Bruno K Ray Chaudhuri Source Type: research

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