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Source: European Respiratory Journal

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Total 303 results found since Jan 2013.

Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease
Discussion: Advancing age is independently associated with pulmonary arterial compliance in health and disease. In contrast to younger patients, pulmonary arterial compliance does not increase in response to PAH therapy in older patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Swift, A., Lungu, A., Capener, D., Hammerton, C., Rothman, A., Lawrie, A., Elliot, C., Condliffe, R., Kiely, D., Wild, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Pulmonary arteriovenous malformations- Evidence of under recognition in respiratory medicine?
Conclusions: Publication patterns suggest continued under recognition of pulmonary PAVMs in mainstream respiratory medicine, favouring specific inclusion of this relatively common pulmonary vascular condition within Respiratory Medicine curricula.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Shovlin, C., Gossage, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Visual estimate of coronary artery calcium predicts cardiovascular disease in COPD
Conclusions A simple visual score for CAC performs well in predicting prevalent CAD and incident CVD in smokers with and without COPD.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Bhatt, S., Kazerooni, E., Newell, J., Hokanson, J., Budoff, M., Dass, C., Bodduluri, S., Jacobson, F., Yen, A., Dransfield, M., Fuhrman, C., Tashjian, J., Nath, H. Tags: 1.12 Clinical Problems - COPD Source Type: research

Long-term risks of cardiovascular events in patients with chronic kidney disease who survived sepsis
CONCLUSIONS Our findings highlight that sepsis in CKD population was associated with significantly increased risk of cardiovascular events among survivors.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Chu, H., Chen, Y.-T. Tags: 2.1 Acute Critical Care Source Type: research

Pulse wave velocity (PWV) in patients (pts) with moderate COPD and cardiovascular risk: The effect of an inhaled long-acting {beta}2-agonist/corticosteroid (SUMMIT)
Conclusion: In moderate COPD pts with or at high-risk of CVD, baseline PWV was predictive of mortality and CV events but unaffected by inhaled therapy.GSK Funded: 113782/NCT01313676.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Crim, C., Brook, R., Anderson, J., Kilbride, S., Calverley, P., Celli, B., Martinez, F., Vestbo, J., Yates, J., Newby, D. Tags: 5.1 Airway Pharmacology and Treatment Source Type: research

Change in right atrial minimal volume is a prognostic marker in pulmonary arterial hypertension (PAH)
Conclusion Change in minimal right atrial volume predicts mortality and maybe of value in the serial evaluation of patients on PAH therapy.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Tubman, E., Sproson, T., Capener, D., Condliffe, R., Elliot, C., Charalampopolous, A., Kiely, D., Wild, J., Swift, A. Tags: 1.3 Imaging Source Type: research

Patient characteristics of new initiators of glycopyrronium bromide (GLY) - A multinational, multi-database real-world drug-utilization study
Conclusion: In real life, majority of first-time GLY use was in line with product label regarding dosing and COPD severity. More than 1/4 of patients used long-acting bronchodilators before GLY start. Cardiovascular comorbidity was considerable.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Verhamme, K. M. C., De Ridder, M., Pedersen, L., Prieto-Alhambra, D., Lapi, F., Rijnbeek, P., Amar, R. K., Sturkenboom, M. Tags: 5.1 Airway Pharmacology and Treatment Source Type: research

Cardiac adaptations to non-linear aerobic training in patients with COPD
While the cardiac adaptations to exercise training are well documented in healthy individuals, the effects of exercise training on cardiac function in patients with COPD are not well known. The aim of this study was to investigate the effects of aerobic exercise training on the cardiac responses to exercise in patients with COPD. 22 COPD patients and 20 healthy controls underwent incremental exercise testing and echocardiography at rest, 25, 50 and 75% workload maximum (Wmax). Subjects then performed non-linear aerobic exercise training 3x/wk for 8 weeks. Individual slope analysis of heart rate (HR) vs. cardiac output (Q) ...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Gelinas, J., Eves, N. Tags: 4.1 Clinical Physiology, Exercise and Functional Imaging Source Type: research

Contrasting cardiovascular responses to exercise in mitochondrial myopathy and pulmonary arterial hypertension
Conclusion: A greater response of heart rate to oxygen consumption (HR/VO2≥120 beats/L) and the presence of an abnormal plateau of O2pulse during exercise are more frequently found in patients with PAH than MM.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Degani-Costa, L. H., Rodrigues, M. T., Ramos, R. P., Ferreira, E. V. M., Fonseca, A. X. C., Gimenes, A., Bravo, D., Ota-Arakaki, J. S., Neder, J. A., Nery, L. E. Tags: 4.1 Clinical Physiology, Exercise and Functional Imaging Source Type: research

Risk of cardiovascular comorbidities in patients with idiopathic pulmonary fibrosis: Analysis of Medicare data
Conclusions: Newly diagnosed IPF pts are typically sicker than non-IPF pts and have significantly higher rates of CV conditions. The higher rate of CV conditions needs to be taken into consideration for the management and treatment of pts with IPF.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Broder, M., Change, E., Papoyan, E., Popescu, I., Reddy, S., Raimundo, K., Chou, W., Stauffer, J. Tags: 6.1 Epidemiology Source Type: research

Clinical Impact of Gensini score in chronic obstructive pulmonary disease (COPD)
Conclusion: Our data suggest that high Gensini score in COPD was independently associated with cardiac co-morbidities such as triple vessel CAD and myocardial infarction.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Park, J. H., Lee, K. S., Chung, W. Y., Sheen, S., Lee, J. Y., Lim, H.-S., Shin, J.-H., Tahk, S.-J. Tags: 5.2 Monitoring Airway Disease Source Type: research

Varying patterns of hyperpnea during Cheyne-Stokes respiration in heart failure: Implication for cardiac function
In heart failure (HF) patients with Cheyne Stokes respiration (CSR), we have noted 2 patterns of hyperpnea: positive, in which end-expiratory lung volume (EELV) is above functional residual capacity (FRC), and negative, in which EELV falls below FRC [Fig1.a,b]. The latter implies an increase in expiratory intrathoracic pressure, from activation of expiratory muscles. We hypothesized that this may be a compensatory mechanism to support stroke volume (SV) when it is very low, as manifest by longer CSR cycle duration and lung-to-finger circulation time (LFCT) than the positive pattern.Patients with HF underwent polysomnograph...
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Perger, E., Inami, T., Lyons, O., Smith, S., Bradley, T. D. Tags: 4.2 Sleep and Control of Breathing Source Type: research

Impact of sleep disordered breathing on short-term post-operative outcome after elective coronary artery bypass graft surgery: a prospective observational study
Sleep disordered breathing (SDB) is common in patients with coronary disease, but its impact on post-operative recovery after coronary artery bypass graft surgery (CABG) is unclear. We therefore determined the effects of SDB on post-operative outcome after elective CABG. In this prospective two-centre study, 219 patients due to receive elective CABG underwent cardiorespiratory polygraphy for SDB prior to surgery and were monitored for post-operative complications. The primary end-point was a composite of 30-day mortality or major post-operative complications (cardiac, respiratory, surgical, infectious, acute renal failure ...
Source: European Respiratory Journal - April 5, 2017 Category: Respiratory Medicine Authors: Rupprecht, S., Schultze, T., Nachtmann, A., Rastan, A. J., Doenst, T., Schwab, M., Witte, O. W., Rohe, S., Zwacka, I., Hoyer, H. Tags: Original Articles: Sleep Source Type: research

Management of hypertension in obstructive sleep apnoea: predicting blood pressure reduction under continuous positive airway pressure
Hypertension affects a quarter of the adult population and remains a leading cause of cardiovascular mortality, accounting for 13.5% of all deaths. Half of all strokes and ischaemic heart disease events are attributable to high blood pressure (BP) [1, 2]. Most patients exhibit Grade-I hypertension (systolic BP of 140 to 159 mmHg and/or diastolic BP of 90 to 99 mmHg) without co-existing cardiovascular disease. An active reduction of BP results in a significant reduction in stroke and death [3].
Source: European Respiratory Journal - October 5, 2017 Category: Respiratory Medicine Authors: Tamisier, R., Levy, P. Tags: Sleep medicine Editorial Source Type: research

Association of inflammatory biomarkers with comorbidity in chronic obstructive pulmonary disease - results from the COSYCONET cohort
Conclusion: WBC correlates with disease severity and is associated with relevant comorbidities. Other classical inflammatory biomarkers did not show a clear correlation with COPD severity of existing comorbidity.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Seiler, F., Trudzinski, F. C., Alquadrah, M., Fähndrich, S., Watz, H., Jörres, R. A., Koch, A., Welte, T., Vogelmeier, C. F., Biertz, F., Bals, R. Tags: Monitoring Airway Disease Source Type: research