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Relationship between adherence to the Mediterranean Diet, intracerebral hemorrhage, and its location
DiscussionOur findings regarding the higher prevalence of ICH in patients with lower adherence to MeDi may be related to the fact that patients with lower MeDi Score exhibit a worse cardiovascular risk profile with increased risk factors such as hypertension and dyslipidemia.
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Lipoprotein(a) levels are associated with coronary severity but not with outcomes in Chinese patients underwent percutaneous coronary intervention
ConclusionLp(a) is an independent predictor of the prevalence of more complex coronary artery lesions (SYNTAX score ≥ 23) in patients with PCI. In addition, our study has shown that Lp(a) has no relationship with long-term cardiovascular outcomes in Chinese patients with PCI.
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 27, 2019 Category: Nutrition Source Type: research

Homocysteine level and risk of different stroke types: A meta-analysis of prospective observational studies
Conclusions This meta-analysis indicated that elevated Hcy levels are associated with an increased risk for ischemic strokes and recurrent strokes but had no distinct association with hemorrhagic strokes.
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 6, 2014 Category: Nutrition Source Type: research

Does the Mediterranean Diet counteract the adverse effects of abdominal adiposity?
Conclusions The MeDiet may counteract the harmful effects of increased adiposity on the risk of CVD.
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 12, 2015 Category: Nutrition Source Type: research

Coronary Slow Flow Phenomenon: Not Only Low In Flow Rate But Also In Myocardial Energy Expenditure
Conclusion Myocardial energy consumption as a calculation obtained from TTE parameters, has been reduced in patients with CSFP and had a significant relationship with exercise capacity. Considering the significant correlation with exercise capacity, this parameter seemed to utilize evaluation of myocardial performance and also functional status in another cardiovascular disease.
Source: Nutrition, Metabolism and Cardiovascular Diseases - June 26, 2015 Category: Nutrition Source Type: research

Mild hyponatremia, hypernatremia and incident cardiovascular disease and mortality in older men: a population-based cohort study
Conclusion Mild hyponatremia even within the normal sodium range and hypernatremia are both associated with increased total mortality and major CVD events in older men without CVD which is not explained by known adverse CV risk factors.
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 7, 2015 Category: Nutrition Source Type: research

A genetic marker of hyperuricemia predicts cardiovascular events in a meta-analysis of three cohort studies in high risk patients
Conclusions The T allele of the rs734553 polymorphism in the GLUT9 gene predicts a doubling in the risk for incident cardiovascular events in patients at high cardiovascular risk. Findings in this study are compatible with the hypothesis of a causal role of hyperuricemia in cardiovascular disease in high risk conditions.
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 22, 2015 Category: Nutrition Source Type: research

The “Sapienza University Mortality and Morbidity Event Rate (SUMMER) Study in Diabetes”: Study Protocol
Discussion The “SUMMER study in diabetes” is aimed at identifying new molecular promoters of mortality and major vascular events in patients with T2DM. Most likely, these novel pathogenic factors will be instrumental for unraveling new pathways underlying such dramatic events. In addition, they will also be used as additional markers to increase the performance of already existing risk-scoring models in predicting the above mentioned outcomes in T2DM, as well as in setting up new preventive and treatment strategies, possibly tailored to specific pathogenic backgrounds.
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 9, 2015 Category: Nutrition Source Type: research

The impact of birth weight on cardiovascular disease risk in the Women’s Health Initiative
Conclusion LBW (<6 lbs.) is independently associated with CVD outcomes in the WHI cohort. This finding supports the role of the prenatal and postnatal environment in contributing to the development of adult chronic disease.
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 18, 2015 Category: Nutrition Source Type: research

The impact of birth weight on cardiovascular disease risk in the Women's Health Initiative
Conclusion LBW (<6 lbs.) is independently associated with CVD outcomes in the WHI cohort. This finding supports the role of the prenatal and postnatal environment in contributing to the development of adult chronic disease.
Source: Nutrition, Metabolism and Cardiovascular Diseases - December 19, 2015 Category: Nutrition Source Type: research

Novel antidiabetic drugs and cardiovascular risk: primum non nocere
Conclusions Results of safety outcome studies focused on CV events, including HF and mortality for CV causes, are not homogeneous. A critical analysis of these studies may help cardiologists and diabetes specialists to adapt their therapeutic choices to individual patients.
Source: Nutrition, Metabolism and Cardiovascular Diseases - June 15, 2016 Category: Nutrition Source Type: research

Homocysteine Concentration in Coronary Artery Disease: Influence of Three Common Single Nucleotide Polymorphisms
Conclusion Homocysteine level is a strong predictor of CV events. Subjects with and without CAD and SNPs in the enzyme MTHFR had increased homocysteine levels. This was not observed for MS and CBS SNPs. Although MTHFR SNPs alter homocysteine levels in patients and controls, these polymorphisms had no impact on prognosis in CAD patients.
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 17, 2016 Category: Nutrition Source Type: research

The PREDIMED trial, Mediterranean diet and health outcomes: How strong is the evidence?
Conclusions The PREDIMED study was designed to overcome three major problems of previous nutritional research: a) residual confounding, addressed by using a randomized design; b) single-nutrient approaches, by randomizing an overall dietary pattern; and c) the limitations of assessing only intermediate risk markers, by using hard clinical end-points.
Source: Nutrition, Metabolism and Cardiovascular Diseases - June 11, 2017 Category: Nutrition Source Type: research

Sun exposure influences the prognostic power of components of mineral metabolism in patients with coronary artery disease
Conclusions In patients with stable CAD, low calcidiol and high FGF-23 plasma levels predict an adverse prognosis only when the sample is obtained during the months with LSE. SE should be taken into account in the clinical practice.
Source: Nutrition, Metabolism and Cardiovascular Diseases - June 16, 2017 Category: Nutrition Source Type: research

Sex differences in associations between blood lipids and cerebral small vessel disease
Conclusions Our findings demonstrate that sex differences may exist in the associations between lipids and SVD. HDL-C and apoA-1 levels were inversely associated with the severity of PVWMLs and DWMLs in women.
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 10, 2017 Category: Nutrition Source Type: research

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