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Source: Neuroscience Letters
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Total 146 results found since Jan 2013.
The mTOR cell signaling pathway is crucial to the long-term protective effects of ischemic postconditioning against stroke
Publication date: 29 May 2018 Source:Neuroscience Letters, Volume 676 Author(s): Peng Wang, Rong Xie, Michelle Cheng, Robert Sapolsky, Xunming Ji, Heng Zhao Ischemic postconditioning (IPostC) protects against stroke, but few have studied the pathophysiological mechanisms of its long-term protective effects. Here, we investigated whether the mTOR pathway is involved in the long-term protective effects of IPostC. Stroke was induced in rats by distal middle cerebral artery occlusion (dMCAo) combined with 30 min of bilateral common carotid artery (CCA) occlusion, and IPostC was induced after the CCA release. Injury size and...
Source: Neuroscience Letters - April 25, 2018 Category: Neuroscience Source Type: research
Vitamin D status and its association with season, depression in stroke
ConclusionsVitamin D deficiency and insufficiency occur at high rates in acute stroke patients. Low serum vitamin D levels were associated with depression in patients with acute stroke as analyzed by both the absolute level of vitamin D and month-specific tertiles. Intervention studies are needed to determine the benefits of vitamin D supplementation for depression in poststroke patients.
Source: Neuroscience Letters - October 4, 2018 Category: Neuroscience Source Type: research
Is perception of vertical impaired in individuals with chronic stroke with a history of ‘pushing’?
Publication date: Available online 7 February 2015 Source:Neuroscience Letters Author(s): Avril Mansfield , Lindsey Fraser , Roshanth Rajachandrakumar , Cynthia J. Danells , Svetlana Knorr , Jennifer Campos Post-stroke ‘pushing’ behaviour appears to be caused by impaired perception of vertical in the roll plane. While pushing behaviour typically resolves with stroke recovery, it is not known if misperception of vertical persists. The purpose of this study was to determine if perception of vertical is impaired amongst stroke survivors with a history of pushing behaviour. Fourteen individuals with chronic stroke (7 wit...
Source: Neuroscience Letters - February 9, 2015 Category: Neuroscience Source Type: research
Role of contralesional hemisphere in paretic arm reaching in patients with severe arm paresis due to stroke: A preliminary report
Publication date: 23 March 2016 Source:Neuroscience Letters, Volume 617 Author(s): Sambit Mohapatra, Rachael Harrington, Evan Chan, Alexander W. Dromerick, Erika Y. Breceda, Michelle Harris-Love Stroke is highly prevalent and a leading cause of serious, long-term disability among American adults. Impaired movement (i.e. paresis) of the stroke-affected arm is a major contributor to post-stroke disability, yet the mechanisms of upper extremity motor recovery are poorly understood, particularly in severely impaired patients who lack hand function. To address this problem, we examined the functional relevance of the co...
Source: Neuroscience Letters - February 18, 2016 Category: Neuroscience Source Type: research
Longitudinal study on modulated corticospinal excitability throughout recovery in supratentorial stroke
This study demonstrates the quick improvement in the CSE via estimation of interhemispheric asymmetry; however, the recovery in the asymmetry continues to normalize even after reaching the threshold for normal values in CSE.
Source: Neuroscience Letters - February 18, 2016 Category: Neuroscience Source Type: research
The effects of cognitive versus motor demands on postural performance and weight bearing asymmetry in patients with stroke
Publication date: 17 October 2017 Source:Neuroscience Letters, Volume 659 Author(s): Hossein Negahban, Masoome Ebrahimzadeh, Mohammad Mehravar While several studies have investigated the interaction between postural control and secondary cognitive tasks in stroke patients, little is known about the influence of secondary motor task on postural control in these patients. The current research was designed to further examine dual-task performance by comparing the effects of cognitive versus motor dual-tasks on postural performance and weight bearing asymmetry (WBA) in stroke patients (n=23) relative to healthy, matched contr...
Source: Neuroscience Letters - September 8, 2017 Category: Neuroscience Source Type: research
Non-invasive brain stimulation to enhance cognitive rehabilitation after stroke
Publication date: Available online 28 June 2018Source: Neuroscience LettersAuthor(s): Laurijn R. Draaisma, Maximilian J. Wessel, Friedhelm C. HummelAbstractStroke is the main cause for long-term disability. Stroke symptoms cover various domains, e.g., motor, sensory, language, or other cognitive functions. In clinical practice and rehabilitation research, especially motor impairment attracts much attention. However, also cognitive impairments are common after stroke, effecting approximately two-thirds of stroke patients in the acute phase. Although 30% of stroke patients spontaneously recover from their cognitive impairmen...
Source: Neuroscience Letters - July 5, 2018 Category: Neuroscience Source Type: research
Visual processing features in patients with visual spatial neglect recovering from right-hemispheric stroke
ConclusionsOur findings support the use of the event-related potential as a tool for investigating rapid recovery from VSN after stroke and suggest that other factors, such as an asymmetrical omission toward the contralateral side or impairment in the temporal processing capacity, might also be potential biomarkers of recovery.
Source: Neuroscience Letters - October 2, 2019 Category: Neuroscience Source Type: research
Bimanual force variability in chronic stroke: With and without visual information
This study investigated bimanual force control in chronic stroke individuals while manipulating visual information. Nine chronic stroke individuals and nine age-matched controls executed bimanual wrist and finger extension at 5% of maximum voluntary contraction. Bimanual force control outcome measures included: (a) coefficient of variation, (b) approximate entropy, and (c) bimanual coordination. Without visual information, chronic stroke individuals displayed less force variability and more regular force production in comparison to age-matched controls. These findings suggest that chronic stroke individuals depended on vis...
Source: Neuroscience Letters - December 29, 2014 Category: Neuroscience Source Type: research
Fluoxetine enhanced neurogenesis is not translated to functional outcome in stroke rats
Publication date: 31 August 2015 Source:Neuroscience Letters, Volume 603 Author(s): Xiaoyu Sun, Xuan Sun, Tingting Liu, Mei Zhao, Shanshan Zhao, Ting Xiao, Jukka Jolkkonen, Chuansheng Zhao Fluoxetine is widely used in clinical practice. It regulates hippocampal neurogenesis, however, the effect of fluoxetine on neurogenesis in the subventricular zone (SVZ) remains controversial. We aimed to study the effect of fluoxetine on neurogenesis in the SVZ and subgranular zone (SGZ) of dentate gyrus (DG) in relation to behavioral recovery after stroke in rats. Adult male Wistar rats were randomly assigned to four groups: ...
Source: Neuroscience Letters - July 25, 2015 Category: Neuroscience Source Type: research
Functional lateralization in cingulate cortex predicts motor recovery after basal ganglia stroke
Publication date: 2 February 2016 Source:Neuroscience Letters, Volume 613 Author(s): Yao Li, Zengai Chen, Xin Su, Xiaoliu Zhang, Ping Wang, Yajing Zhu, Qun Xu, Jianrong Xu, Shanbao Tong The basal ganglia (BG) is involved in higher order motor control such as movement planning and execution of complex motor synergies. Neuroimaging study on stroke patients specifically with BG lesions would help to clarify the consequence of BG damage on motor control. In this paper, we performed a longitudinal study in the stroke patients with lesions in BG regions across three motor recovery stages, i.e., less than 2week (Sessio...
Source: Neuroscience Letters - January 13, 2016 Category: Neuroscience Source Type: research
Evaluating interhemispheric cortical responses to transcranial magnetic stimulation in chronic stroke: A TMS-EEG investigation
Publication date: 8 April 2016 Source:Neuroscience Letters, Volume 618 Author(s): Michael R. Borich, Lewis A. Wheaton, Sonia M. Brodie, Bimal Lakhani, Lara A. Boyd TMS-evoked cortical responses can be measured using simultaneous electroencephalography (TMS-EEG) to directly quantify cortical connectivity in the human brain. The purpose of this study was to evaluate interhemispheric cortical connectivity between the primary motor cortices (M1s) in participants with chronic stroke and controls using TMS-EEG. Ten participants with chronic stroke and four controls were tested. TMS-evoked responses were recorded at rest a...
Source: Neuroscience Letters - March 4, 2016 Category: Neuroscience Source Type: research
Goal conceptualization and symmetry of arm movements affect bimanual coordination in individuals after stroke
Publication date: 28 July 2016 Source:Neuroscience Letters, Volume 626 Author(s): Shailesh Kantak, Robert McGrath, Nazaneen Zahedi Coordination during goal-directed movements emerges from an interaction of task and individual constraints. It is not known how individuals with unilateral stroke and age-matched controls coordinate their arms when performing symmetric and asymmetric movements to accomplish common task goals compared to independent task goals. Eleven individuals with chronic stroke and ten age-matched controls executed a bimanual task under virtual conditions that allowed systematic manipulation of symmetr...
Source: Neuroscience Letters - May 27, 2016 Category: Neuroscience Source Type: research
Proximal arm non-use when reaching after a stroke
Publication date: 14 September 2017 Source:Neuroscience Letters, Volume 657 Author(s): K.K.A. Bakhti, D. Mottet, N. Schweighofer, J. Froger, I. Laffont After a stroke, many people “cannot and do not” use their paretic upper limb. With recovery, some people “can but do not” use their paretic upper limb and this non-use should be counteracted with specific rehabilitation. The aim of the study was to quantify one aspect of the non-use: proximal arm non-use when reaching within one’s arm length in 45 post-stroke and 45 age matched controls. Arm use refers to the contribution of the shoulder and elbow motion to the h...
Source: Neuroscience Letters - August 10, 2017 Category: Neuroscience Source Type: research
