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Source: GEO: Gene Expression Omnibus
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Total 163 results found since Jan 2013.
GSE216349 TMAO promotes NLRP3 inflammasome activation of microglia aggravating neurological injury in stroke through FTO/IGF2BP2
In conclusion, these results demonstrated that TMAO promotes NLRP3 inflammasome activation of microglia aggravating neurological injury in stroke through FTO/IGF2BP2.
Source: GEO: Gene Expression Omnibus - September 6, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE202709 Clinical significance of MSP-RON signaling based on mRNA-microRNA integration analyses in acute severe ischemic stroke patients
Series Type : Expression profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - August 13, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Non-coding RNA profiling by high throughput sequencing Homo sapiens Source Type: research
GSE179645 Screening for differentially expressed circRNAs in ischemic stroke by RNA sequencing
In this study, RNA library construction and high-throughput sequencing were performed. The DEmRNA-DElncRNA co-expression analysis showed that there were 19 DElncRNA-DEmRNA relationship pairs (including 15 DEmRNA, 3 DElncRNA) in the PCI_NR/PCI_Re and NC/PCI_Re intersection group and 993 DElncRNA-DEmRNA relationship pairs (including 74 DEmRNA, 19 DElncRNA) in the NC/ACS and ACS/PCI_NR intersection group. We selected genes in the top 10 of differential expression and those involved in the co-expression of lncRNA-mRNA for diagnostic analysis. The area under curve (AUC) of PDZK1IP1, PROK2 and LAMP3 were greater than 0.7, which ...
Source: GEO: Gene Expression Omnibus - July 31, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Non-coding RNA profiling by high throughput sequencing Homo sapiens Source Type: research
GSE232429 Gene expression profile at single cell level of normal neurons or peri-infarct neurons of Padi4-deficient and wild-type mice on day 4 after ischemic stroke
Contributors : Akari Nakamura ; Seiichiro Sakai ; Yuichiro Hara ; Hideya Kawaji ; Takashi ShichitaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo investigate the gene expression difference in peri-infarct neurons of Padi4-deficient and control mice on day 4 after ischemic stroke onset, we performed gene expression profiling analysis using data obtained from RNA-seq of peri-infarct neurons from neuron-specific Padi4-deficient and control mice.
Source: GEO: Gene Expression Omnibus - July 24, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE232171 Distribution of histone-3-citrullinated sites in peri-infarct neurons on day 4 after ischemic stroke
Contributors : Akari Nakamura ; Seiichiro Sakai ; Jun Tsuyama ; Takashi ShichitaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusTo investigate distribution of histone-H3-citrullinated sites in peri-infarct neurons on day 4 after ischemic stroke and sham-operated mice, we performed cleavage under targets and tagmentation (CUT&Tag) assay for citrullinated histone H3 of peri-infarct neurons from Padi4-dificient or control mice .
Source: GEO: Gene Expression Omnibus - July 24, 2023 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research
GSE232169 Chromatin accessibility in peri-infarct neurons on day 4 after ischemic stroke ATAC-seq
Contributors : Akari Nakamura ; Seiichiro Sakai ; Jun Tsuyama ; Takashi ShichitaSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Mus musculusTo investigate chromatin accessibility in peri-infarct neurons on day 4 after ischemic stroke, we performed assay for transposase-accessible chromatin with sequencing (ATAC-seq) in peri-infarct neurons from Padi4 non-dificient mice.
Source: GEO: Gene Expression Omnibus - July 24, 2023 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Mus musculus Source Type: research
GSE231718 Differential gene expression in peri-infarct neurons compared between Padi4-deficient and wild-type mice on day 4 after ischemic stroke
Contributors : Akari Nakamura ; Seiichiro Sakai ; Takashi ShichitaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo investigate the gene expression difference in peri-infarct neurons compared between Padi4-deficient and wild-type mice on day 4 after ischemic stroke onset, we performed gene expression profiling analysis using data obtained from RNA-seq of peri-infarct neurons collected from neuron-specific Padi4-deficient and control mice.
Source: GEO: Gene Expression Omnibus - July 24, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE231400 Differential gene expression in peri-infarct neurons of 15-HETrE-administered mice (compared with vehicle-administered mice) on day 4 after ischemic stroke onset
Contributors : Akari Nakamura ; Seiichiro Sakai ; Takashi ShichitaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo investigate the gene expression difference in peri-infarct neurons of vehicle- and 15-HETrE-administered mice on day 4 after ischemic stroke onset, we performed gene expression profiling analysis using data obtained from RNA-seq of peri-infarct neurons collected from the brain of vehicle- and 15-HETrE-administered mice.
Source: GEO: Gene Expression Omnibus - July 24, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE230996 Differential gene expression in brain tissues of Pla2g2e-deficient and wild-type mice on day 3 after ischemic stroke onset
Contributors : Akari Nakamura ; Yasumasa Nishito ; Takashi ShichitaSeries Type : Expression profiling by arrayOrganism : Mus musculusTo investigate the gene expression in brain tissues of Pla2g2e-deficient and wild-type mice on day 3 after ischemic stroke onset, we performed gene expression profiling analysis using data obtained from Microarray of brain tissues from Pla2g2e-deficient and wild-type mice.
Source: GEO: Gene Expression Omnibus - July 24, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
GSE225671 The role of stromal and immune cells in atrial disease III
Contributors : Maarten Hulsmans ; Maximilian J Schloss ; I-Hsiu Lee ; Kamila Naxerova ; Matthias NahrendorfSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn atrial fibrillation, disturbed electrical conduction disrupts the coordinated contraction of the heart ’s antechambers, increasing the risk of stroke and heart failure. The rising prevalence of this disease approaches 9% in patients>65 years. Studying freshly isolated human atrial tissue and a new mouse model, we here decipher how immune and stromal cells contribute to the structural tissue remodeling that underlies atrial fibr...
Source: GEO: Gene Expression Omnibus - July 13, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE224947 The role of stromal and immune cells in atrial disease II
Contributors : Maarten Hulsmans ; Maximilian J Schloss ; I-Hsiu Lee ; Kamila Naxerova ; Matthias NahrendorfSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusIn atrial fibrillation, disturbed electrical conduction disrupts the coordinated contraction of the heart ’s antechambers, increasing the risk of stroke and heart failure. The rising prevalence of this disease approaches 9% in patients>65 years. Studying freshly isolated human atrial tissue and a new mouse model, we here decipher how immune and stromal cells contribute to the structural tissue remodeling that underlies atrial fibr...
Source: GEO: Gene Expression Omnibus - July 13, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
GSE197518 The role of stromal and immune cells in atrial disease I
Contributors : Maarten Hulsmans ; Maximilian J Schloss ; I H Lee ; George Tolis ; Serguei Melnitchouk ; Kamila Naxerova ; Matthias NahrendorfSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiens ; Mus musculusIn atrial fibrillation, disturbed electrical conduction disrupts the coordinated contraction of the heart ’s antechambers, increasing the risk of stroke and heart failure. The rising prevalence of this disease approaches 9% in patients>65 years. Studying freshly isolated human atrial tissue and a new mouse model, we here decipher how immune and stromal cells contribute to the struct...
Source: GEO: Gene Expression Omnibus - July 13, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Mus musculus Source Type: research
GSE154326 Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension Illumina
Contributors : Katja Grabowski ; Reinhold Kreutz ; Anika Witten ; Monika StollSeries Type : Expression profiling by arrayOrganism : Rattus norvegicusTo identify novel targets in left ventricular (LV) hypertrophy (LVH) we initiated comparative transcriptome analysis between genetic models derived from stroke-prone spontaneously hypertensive rats (SHRSP) and Fischer (F344). Previous genetic studies in the SHRSP/F344 model confirmed the presence of a major quantitative trait locus (QTL) for LV mass on rat chromosome (RNO) 1. We assigned carboxypeptidase X 2 (Cpxm2) to a genetic locus for LV mass identified in SHRSP. We assign...
Source: GEO: Gene Expression Omnibus - July 10, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Rattus norvegicus Source Type: research
GSE154312 miRNA profiles of natural recovery in vitreous humor after NAION induction in rat
Contributors : Yihsun Chen ; Yaotseng WenSeries Type : Non-coding RNA profiling by arrayOrganism : Rattus norvegicus ; synthetic constructWe collected some vitreous humors from rat eyes through a photolabile paper based chip which experienced different natural recovery processes at day 0, 0.25, 1, 3, 7 day after eye stroke by laser induced in rat. These mirs samples were collected from extracelluar vesicles of vitreous humor in rat.We used microarray to find some new miRNAs that may participate in the natural recovery process after experience eye stroke.
Source: GEO: Gene Expression Omnibus - June 30, 2023 Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by array Rattus norvegicus synthetic construct Source Type: research
GSE234052 The transcriptional landscape of pericytes in acute ischemic stroke
This study identifies temporal transcriptional changes in the acute phase of ischemic stroke that reflect the early response of pericytes to the ischemic insult and its secondary consequences and may constitute potential future therapeutic targets.
Source: GEO: Gene Expression Omnibus - June 29, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
